A high TP53 mutation burden is a strong predictor of primary refractory mantle cell lymphoma

. 2020 Dec ; 191 (5) : e103-e106. [epub] 20200830

Jazyk angličtina Země Anglie, Velká Británie Médium print-electronic

Typ dokumentu dopisy, práce podpořená grantem

Perzistentní odkaz   https://www.medvik.cz/link/pmid32862455

Grantová podpora
PROGRES Q26/LF1 Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
PROGRES Q28/LF1 Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
IGA_LF_2020_002 Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
IGA_LF_2020_016 Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
MH CZ - DRO (FNOL, 00098892) Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
AZV16-32339A Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
AZV16-31092A Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports
RVO-VFN64165 Ministry of Health of the Czech Republic, and the Ministry of Education, Youth and Sports

Zobrazit více v PubMed

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Delfau-Larue M-H, Klapper W, Berger F, Jardin F, Briere J, Salles G, et al. High-dose cytarabine does not overcome the adverse prognostic value of CDKN2A and TP53 deletions in mantle cell lymphoma. Blood. 2015;126:604-11.

Obr A, Procházka V, Jirkuvová A, Urbánková H, Kriegova E, Schneiderová P, et al. TP53 mutation and complex karyotype portends a dismal prognosis in patients with mantle cell lymphoma. Clin Lymphoma Myeloma Leuk. 2018;18:762-8.

Aukema SM, Hoster E, Rosenwald A, Canoni D, Delfau-Larue MH, Rymkiewicz G, et al. Expression of TP53 is associated with the outcome of MCL independent of MIPI and Ki-67 in trials of the European MCL Network. Blood. 2018;131:417-20.

Di Agostino S, Fontemaggi G, Strano S, Blandino G, D'Orazi G. Targeting mutant p53 in cancer: the latest insights. J Exp Clin Cancer Res. 2019;38:290.

Lin RJ, Ho C, Hilden PD, Barker JN, Giralt SA, Hamlin PA, et al. Allogeneic haematopoietic cell transplantation impacts on outcomes of mantle cell lymphoma with TP 53 alterations. Br J Haematol. 2019;184:1006-10.

Hanna KS, Campbell M, Husak A, Sturm S. The role of Bruton’s tyrosine kinase inhibitors in the management of mantle cell lymphoma. J Oncol Pharm Pract. 2020;26:1190-9.

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