Effects of a 12-Week Interventional Exercise Programme on Muscle Strength, Mobility and Fitness in Patients With Diabetic Foot in Remission: Results From BIONEDIAN Randomised Controlled Trial
Jazyk angličtina Země Švýcarsko Médium electronic-ecollection
Typ dokumentu časopisecké články, randomizované kontrolované studie, práce podpořená grantem
PubMed
35865313
PubMed Central
PMC9294221
DOI
10.3389/fendo.2022.869128
Knihovny.cz E-zdroje
- Klíčová slova
- diabetes mellitus, diabetic foot, education, exercise, physical activity,
- MeSH
- cvičení fyziologie MeSH
- diabetes mellitus 2. typu * komplikace terapie MeSH
- diabetická noha * terapie MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- svalová síla fyziologie MeSH
- terapie cvičením MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
OBJECTIVES: Diabetic foot syndrome (DFS) is a serious late diabetic complication characterised by limited joint mobility and other biomechanical and muscle abnormalities. AIM: To evaluate the effect of an interventional exercise programme on anthropometric parameters, muscle strength, mobility and fitness in patients with diabetic foot in remission. DATA SOURCES AND STUDY SELECTION: Thirty-eight patients with type 2 diabetes and DFS without active lesions (mean age 65 ± 6.9 years, BMI 32 ± 4.7 kg.m-2, waist-hip ratio (WHR)1.02 ± 0.06) were enrolled in our randomised controlled trial. All subjects were randomised into two groups: an intervention group (I; n=19) and a control group (C; n=19). The 12-week exercise intervention focused on ankle and small-joint mobility in the foot, strengthening and stretching of the lower extremity muscles, and improvements in fitness. Changes (Δ=final minus initial results) in physical activity were assessed using the International Physical Activity Questionnaire (IPAQ), with joint mobility detected by goniometry, muscle strength by dynamometry, and fitness using the Senior Fitness Test (SFT). DATA EXTRACTION: Due to reulceration, 15.8% of patients from group I (3/19) and 15.8% of patients from group C were excluded. Based on the IPAQ, group I was more active when it came to heavy (p=0.03) and moderate physical activity (p=0.06) after intervention compared to group C. Group I improved significantly in larger-joint flexibility (p=0.012) compared to controls. In group I, dynamometric parameters increased significantly in both lower limbs (left leg; p=0.013, right leg; p=0.043) compared to group C. We observed a positive trend in the improvement of fitness in group I compared to group C. We also confirmed positive correlations between heavy physical activity and selected parameters of flexibility (r=0.47; p=0.007), SFT (r=0.453; p=0.011) and dynamometry (r=0.58; p<0.0025). Anthropometric parameters, such as BMI and WHR, were not significantly influenced by the intervention programme. CONCLUSION: Our 12-week interventional exercise programme proved relatively safe, resulting in improved body flexibility and increased muscle strength in DF patients in remission.
2nd Faculty of Medicine Charles University Prague Czechia
Clinical Rehabilitation Division Institute for Clinical and Experimental Medicine Prague Czechia
Diabetes Centre Institute for Clinical and Experimental Medicine Prague Czechia
Faculty of Physical Education and Sport Charles University Prague Czechia
Zobrazit více v PubMed
Francia P, Anichini R, Seghieri G, De Bellis A, Gulisano M. History, Prevalence and Assessment of Limited Joint Mobility, From Stiff Hand Syndrome to Diabetic Foot Ulcer Prevention: A Narrative Review of the Literature. Curr Diabetes Rev (2018) 14(5):411–26. doi: 10.2174/1573399813666170816142731 PubMed DOI PMC
Gnanasundaram S, Ramalingam P, Das BN, Viswanathan V. Gait Changes in Persons With Diabetes: Early Risk Marker for Diabetic Foot Ulcer. Foot Ankle Surgery (2020) 26(2):163–8. doi: 10.1016/j.fas.2019.01.005 PubMed DOI
Bus SA, Lavery LA, Monteiro-Soares M, Rasmussen A, Raspovic A, Sacco ICN, et al. . Guidelines on the Prevention of Foot Ulcers in Persons With Diabetes (IWGDF 2019 Update). Diabetes Metab Res Rev (2020) 36 Suppl 1:e3269. doi: 10.1002/dmrr.3269 PubMed DOI
Singh N, Armstrong DG, Lipsky BA. Preventing Foot Ulcers in Patients With Diabetes. J Am Med Assoc (2005) 293(2):217–28. doi: 10.1001/jama.293.2.217 PubMed DOI
Lechleitner M, Abrahamian H, Francesconi C, Kofler M, Sturm W, Köhler G, et al. . Diabetic Neuropathy and Diabetic Foot Syndrome (Update 2019). Wiener klinische Wochenschrift (2019) 131(1):141–50. doi: 10.1007/s00508-019-1487-4 PubMed DOI
Van Eetvelde BLM, Lapauw B, Proot P, Vanden Wyngaert K, Celie B, Cambier D, et al. . The Impact of Sensory and/or Sensorimotor Neuropathy on Lower Limb Muscle Endurance, Explosive and Maximal Muscle Strength in Patients With Type 2 Diabetes Mellitus. J Diabetes its Complications (2020) 34(6):107562. doi: 10.1016/j.jdiacomp.2020.107562. ISSN 1056-8727. PubMed DOI
Hochlenert D, Engels G, Morbach S, Schliw S, Game FL. Entities: A System of Diabetic Foot Ulcers. In: Diabetic Foot Syndrome. Cham: Springer; (2018). doi: 10.1007/978-3-319-92055-9_5 DOI
Quast DR, Nauck MA, Bechara FG, Meier JJ. A Case Series of Verrucae Vulgares Mimicking Hyperkeratosis in Individuals With Diabetic Foot Ulcers. Diabetic Med (2017) 34(8):1165–8. doi: 10.1111/dme.13387 PubMed DOI
Singh G, Gupta S, Chanda A. Biomechanical Modelling of Diabetic Foot Ulcers: A Computational Study. J Biomechanics (2021) 127:110699. doi: 10.1016/j.jbiomech.2021.110699 PubMed DOI
Alam U, Riley DR, Jugdey RS, Azmi S, Rajbhandari S, D'Août K, et al. . Diabetic Neuropathy and Gait: A Review. Diabetes Ther (2017) 8:1253–64. doi: 10.1007/s13300-017-0295-y PubMed DOI PMC
IPAQ Research Committee . Guidelines for Data Processing and Analysis of the International Physical Activity Questionnaire. IPAQ; (2005). The International Physical Activity Questionnaire.
Maddison R, Mhurchu CN, Jiang Y, Vander Hoorn S, Rodgers A, Lawes CMM, et al. . International Physical Activity Questionnaire (IPAQ) and New Zealand Physical Activity Questionnaire (NZPAQ): A Doubly Labelled Water Validation. Int J Behav Nutr Phys Activity (2007) 4:62. doi: 10.1186/1479-5868-4-62 PubMed DOI PMC
Tomioka K, Iwamoto J, Saeki K, Okamoto N. Reliability and Validity of the International Physical Activity Questionnaire (IPAQ) in Elderly Adults: The Fujiwara-Kyo Study. J Epidemiol (2011) 21:459–65. doi: 10.2188/jea.JE20110003 PubMed DOI PMC
Rikli R, Jones CJ. Senior Fitness Test Manual. Champaign, IL: Human Kinetics; (2001).
Chlumsky M, Dadova K. Testování Funkční Zdatnosti Seniorů Metodou Senior Fitness Test V Podmínkách Skupinového Cvičení (Skupinových Lekcí). Rehabilitacia (2017) 54(4):259–72.
Rikli R, Jones J. Functional Fitness Normative Scores for Community-Residing Older Adults, Ages 60-94. J Aging Phys Activity (1999) 7(1):162–81. doi: 10.1123/japa.7.2.162 DOI
Rikli R, Jones J. Development and Validation of a Functional Fitness Test for Community-Residing Older Adults. J Aging Phys Activity (1999) 7(1):129–61. doi: 10.1123/japa.7.2.129 DOI
Melenovsky V, Hlavata K, Sedivy P, Dezortova M, Borlaug BA, Petrak J, et al. . Skeletal Muscle Abnormalities and Iron Deficiency in Chronic Heart Failure: An Exercise 31P Magnetic Resonance Spectroscopy Study of Calf Muscle. Circulation: Heart Failure (2018) 11(9). doi: 10.1161/CIRCHEARTFAILURE.117.004800 PubMed DOI
Šedivý P, Kipfelsberger MC, Dezortová M, Krššák M, Drobný M, Chmelík M, et al. . Dynamic 31p MR Spectroscopy of Plantar Flexion: Influence of Ergometer Design, Magnetic Field Strength (3 and 7 T), and RF-Coil Design. Med Physics (2015) 42(4):1678–89. doi: 10.1118/1.4914448 PubMed DOI
Niess F, Fiedler GB, Schmid AI, Laistler E, Frass-Kriegl R, Wolzt M, et al. . Dynamic Multivoxel-Localized 31P MRS During Plantar Flexion Exercise With Variable Knee Angle. NMR Biomedicine (2018) 31(6):e3905. doi: 10.1002/nbm.3905 PubMed DOI PMC
Raymer GH, Allman BL, Rice CL, Marsh GD, Thompson RT. Characteristics of a MR-Compatible Ankle Exercise Ergometer for a 3. 0 T head-only MR scanner. Med Eng Phys (2006) 28(5):489–94. doi: 10.1016/j.medengphy.2005.07.021 PubMed DOI
Lunes DH, Rocha CB, Borges NC, Marcon CO, Pereira VM, Carvalho LC. Self-Care Associated With Home Exercises in Patients With Type 2 Diabetes Mellitus. PLoS One (2014) 9(12):1–13. doi: 10.1371/journal.pone.0114151 PubMed DOI PMC
Francia P, Anichini R, De Bellis A, Seghieri G, Lazzeri R, Paternostro F, et al. . Diabetic Foot Prevention: The Role of Exercise Therapy in the Treatment of Limited Joint Mobility, Muscle Weakness and Reduced Gait Speed. Ital J Anat Embryology (2015) 120(1):21–32. PubMed
Hagedoorn IJM, den Braber N, Oosterwijk MM, Gant CM, Navis G, Vollenbroek-Hutten MMR, et al. . Low Physical Activity in Patients With Complicated Type 2 Diabetes Mellitus is Associated With Low Muscle Mass and Low Protein Intake. J Clin Med (2020) 9(10):3104. doi: 10.3390/jcm9103104 PubMed DOI PMC
Mosalman Hagini M, Mavros Y, Fiatarone Singh MA. The Effects of Structured Exercise or Lifestyle Behavior Interventions on Long-Term Physical Activity Level and Health Outcomes in Individuals With Type 2 Diabetes: A Systematic Review, Meta-Analysis, and Meta-Regression. J Phys Activity Health (2018) 15(9):697–707. doi: 10.1123/jpah.2017-0589 PubMed DOI
Yom-Tov E, Feraru G, Kozdoba M, Mannor S, Tennenholtz M, Hochberg I. Encouraging Physical Activity in Patients With Diabetes: Intervention Using a Reinforcement Learning System. J Med Internet Res (2017) 19(10):1–13. doi: 10.2196/jmir.7994 PubMed DOI PMC
Diabetes Canada Clinical Practice Guidelines Expert Committee. RJ S, MJ A, SL B, NG Boulé, Dasgupta K, et al. . Physical Activity and Diabetes. Can J Diabetes (2018) 42(1):S54–63. doi: 10.1016/j.jcjd.2017.10.008 PubMed DOI
Gray N, Picone G, Sloan F, Yashkin A. Relation Between BMI and Diabetes Mellitus and its Complications Among US Older Adults. South Med J (2015) 108(1):29–36. doi: 10.14423/SMJ.0000000000000214 PubMed DOI PMC
Francia P, Gulisano M, Anichini R, Seghieri G. Diabetic Foot and Exercise Therapy: Step by Step the Role of Rigid Posture and Biomechanics Treatment. Curr Diabetes Rev (2014) 10:86–99. doi: 10.2174/1573399810666140507112536 PubMed DOI PMC
Matsui N, Miaki H, Kitagawa T, Nakagawa T. Relationship Between Range of Motion of Foot Joints and Amount of Physical Activity in Middle-Aged Male Diabetic Patients. J Phys Ther Science (2019) 31(7):540–4. doi: 10.1589/jpts.31.540 PubMed DOI PMC
Zimny S, Schatz H, Pfohl M. The Role of Limited Joint Mobility in Diabetic Patients With an at-Risk Foot. Diabetes Care (2004) 27(4):942–6. doi: 10.2337/diacare.27.4.942 PubMed DOI
Armstrong DG, Lavery LA, Holtz-Neiderer K, Mohler MJ, Wendel CS, Nixon BP, et al. . Variability in Activity may Precede Diabetic Foot Ulceration. Diabetes Care (2004) 27(8):1980–4. doi: 10.2337/diacare.27.8.1980 PubMed DOI
Lemaster JW, Reiber GE, Smith DG, Heagerty PJ, Wallace C. Daily Weight-Bearing Activity Does Not Increase the Risk of Diabetic Foot Ulcers. Med Sci Sports Exercise (2003) 35(7):1093–9. doi: 10.1249/01.MSS.0000074459.41029.75 PubMed DOI
Mueller MJ, Maluf KS. Tissue Adaptation to Physical Stress: A Proposed “Physical Stress Theory” to Guide Physical Therapist Practice, Education, and Research. Phys Ther (2002) 82(4):383–403. doi: 10.1093/ptj/82.4.383 PubMed DOI
Crews RT, Schneider KL, Yalla SV, Reeves ND, Vileikyte L. Physiological and Psychological Challenges of Increasing Physical Activity and Exercise in Patients at Risk of Diabetic Foot Ulcers: A Critical Review. Diabetes/Metabolism Res Rev (2016) 32(8):791–804. doi: 10.1002/dmrr.2817 PubMed DOI PMC
Lemaster JW, Kueller JM, Reiber EG, Mehr DR, Madsen RW, Conn VS. Effect of Weight-Bearing Activity on Foot Ulcer Incidence in People With Diabetic Peripheral Neuropathy: Feet First Randomized Controlled Trial. Phys Ther (2008) 88(11):1385–98. doi: 10.2522/ptj.20080019 PubMed DOI
Alothman S, Alshehri MM, Alenazi AM, Rucker J, Kluding PM. The Association Between Sedentary Behavior and Health Variables in People With Type 2 Diabetes. Health Behav Policy Review (2020) 7(3):198–209. doi: 10.14485/HBPR.7.3 DOI
Cavegn EI, Riskowski JL. The Effects of Tai Chi on Peripheral Somatosensation, Balance, and Fitness in Hispanic Older Adults With Type 2 Diabetes: A Pilot and Feasibility Study. Evidence-Based Complementary Altern Med (2015) 2015:767213. doi: 10.1155/2015/767213 PubMed DOI PMC
Wehmeyer C, Loots J, Nortje L, Lategan L. The Effects of Supervised Exercise Training and Self-Directed Active Daily Living on Fitness and Health Parameters in Elderly Males With Type II Diabetes. Afr J Physical Health Education Recreation Dance (2014) 20):1424–35.
Ricci PA, Cabiddu R, Jürgensen SP, André LD, Oliveira CR, Di Thommazo-Luporini L, et al. . Validation of the Two-Minute Step Test in Obese With Comorbibities and Morbidly Obese Patients. Braz J Med Biol Res (2019) 52(9):e8402. doi: 10.1590/1414-431X20198402 PubMed DOI PMC
Wegrzynowska-Teodorczyk K, Mozdzanowska D, Josiak K, Siennicka (Rydlewska) A, Nowakowska K, et al. . Could the Two-Minute Step Test be an Alternative to the Six-Minute Walk Test for Patients With Systolic Heart Failure? Eur J Prev Cardiol (2016) 23. doi: 10.1177/2047487315625235 PubMed DOI
Chow JLJ, Tony S, Chow Y, Tan D, Rand S, Fitzgerald C. The 2 Minute Step Test: A Reliable and Valid Alternative to the 6 Minute Walk Test in Measuring Aerobic Capacity of Older Adults Post Coronary Revascularisation. Conference: EuroPrevent (European Journal of Preventive Cardiology) At: Malaga (2017) 24(Supplement 1):79.
Allet L, Armand S, de Bie RA, Golay A, Monnin D, Aminian K, et al. . The Gait and Balance of Patients With Diabetes can be Improved: A Randomised Controlled Trial. Diabetologia (2010) 53(3):458–66. doi: 10.1007/s00125-009-1592-4 PubMed DOI PMC
Balducci S, Iacobellis G, Parisi L, Di Biase N, Calandriello E, Leonetti F, et al. . Exercise Training can Modify the Natural History of Diabetic Peripheral Neuropathy. J Diabetes Complications (2006) 20(4):216–23. doi: 10.1016/j.jdiacomp.2005.07.005 PubMed DOI
Kluding PM, Bareiss SK, Hastings M, Marcus RL, Sinacore DR, Mueller MJ. Physical Training and Activity in People With Diabetic Peripheral Neuropathy: Paradigm Shift. Phys Ther (2017) 97(1):31–43. doi: 10.2522/ptj.20160124 PubMed DOI PMC
Kluding PM, Pasnoor M, Singh R, Jernigan S, Farmer K, Rucker J, et al. . The Effect of Exercise on Neuropathic Symptoms, Nerve Function, and Cutaneous Innervation in People With Diabetic Peripheral Neuropathy. J Diabetes Complications (2012) 26(5):424–9. doi: 10.1016/j.jdiacomp.2012.05.007 PubMed DOI PMC
Otterman NM, van Schie CH, van der Schaaf M, van Bon AC, Busch-Westbroek TE, Nollet F. An Exercise Programme for Patients With Diabetic Complications: A Study on Feasibility and Preliminary Effectiveness. Diabetes Med (2011) 28(2):212–7. doi: 10.1111/j.1464-5491.2010.03128.x PubMed DOI
Rikli R, Jones J. Assessing Physical Performance in Independent Older Adults: Issues and Guidelines. J Aging Phys Activity (1997) 5:244–61. doi: 10.1123/japa.5.3.244 DOI
Jones CJ, Rikli RE. The Application of Fullerton’s Functional Fitness Test for Older Adults in a Group Setting. In: Science and Sports, vol. 15. (2000). p. 194–7. doi: 10.1016/S0765-1597(00)80005-2 DOI
Jones CJ, Rikli RE. Measuring Functional Fitness in Older Adults. J Active Ageing (2002), 25–30.
Langhammer B, Stanghelle JK. Functional Fitness in Elderly Norwegians Measured With the Senior Fitness Test. Eur J Physiotherapy (2011) 13(4):137–44. doi: 10.3109/14038196.2011.616913 DOI
Åström MJ, von Bonsdorff MB, Perälä MM, Salonen MK, Rantanen T, Kajantie E, et al. . Glucose Regulation and Physical Performance Among Older People: The Helsinki Birth Cohort Study. Acta Diabetologica (2018) 55:1051–8. doi: 10.1007/s00592-018-1192-1 PubMed DOI PMC
McGuire J, Thomson A, Kennedy PG. The Biomechanics of Diabetic Foot Amputation. Wounds. (2021) 14:WNDS20210414-2. Epub ahead of print. PubMed
Boulton AJM, Rayman G, Wukich DK. The Foot in Diabetes, Fifth Edition. USA: ISBN 9781119445814: John Wiley; (2020).
Lázaro-Martínez JL, Aragón-Sánchez J, Álvaro-Afonso FJ, García-Morales E, García-Álvarez Y, Molines-Barroso RJ. The Best Way to Reduce Reulcerations: If You Understand Biomechanics of the Diabetic Foot, You can do it. Int J Lower Extremity Wounds (2014) 13(4):294–319. doi: 10.1177/1534734614549417 PubMed DOI
Van Schie CHM. A Review of the Biomechanics of the Diabetic Foot. Int J Lower Extremity Wounds (2005) 4(3):160–70. doi: 10.1177/1534734605280587 PubMed DOI
Wiszomirska I, Kaczmarczyk K, Błażkiewicz M, Wit A. The Impact of a Vestibular-Stimulating Exercise Regime on Postural Stability in People With Visual Impairment. BioMed Res Int (2015) 2015:136969. doi: 10.1155/2015/136969 PubMed DOI PMC
Fejfarová F, Jirkovská A, Dragomirecká E, Game F, Bém R, Dubský M, et al. . Does the Diabetic Foot Have a Significant Impact on Selected Psychological or Social Characteristics of Patients With Diabetes Mellitus? J Diabetes Res (2014) 2014:371938. doi: 10.1155/2014/371938 PubMed DOI PMC