UNLABELLED: The aim of our case-control study was to compare selected psychological and social characteristics between diabetic patients with and without the DF (controls). METHODS: 104 patients with and 48 without DF were included into our study. Both study groups were compared in terms of selected psychosocial characteristics. RESULTS: Compared to controls, patients with DF had a significantly worse quality of life in the area of health and standard of living as shown by lower physical health domain (12.7 ± 2.8 versus 14.7 ± 2.5; P < 0.001) and environment domain (14.1 ± 2.2 versus 15 ± 1.8; P < 0.01) that negatively correlated with diabetes duration (r = -0.061; P = 0.003). Patients with DF subjectively felt more depressed in contrast to controls (24.5 versus 7.3%; P < 0.05); however, the depressive tuning was objectively proven in higher percentage in both study groups (83.2 versus 89.6; NS). We observed a significantly lower level of achieved education (P < 0.01), more patients with disability pensions (P < 0.01), and low self-support (P < 0.001) in patients with the DF compared to controls. In the subgroup of patients with a previous major amputation and DF (n = 6), there were significantly worse outcomes as in the environment domain (P < 0.01), employment status, and stress readaptation (P < 0.01) in contrast to the main study groups. CONCLUSIONS: Patients with DF had a predominantly worse standard of living. In contrast to our expectations, patients with DF appeared to have good stress tolerability and mental health (with the exception of patients with previous major amputation) and did not reveal severe forms of depression or any associated consequences.

Center for Lower Extremity Ambulatory Research Dr William M Scholl College of Podiatric Medicine Rosalind Franklin University of Medicine and Science Chicago IL 60064 USA

Department of Social Work Faculty of Arts Charles University 116 42 Prague Czech Republic

Diabetes Center Institute for Clinical and Experimental Medicine Vídeňská 1958 140 21 Prague Czech Republic

Diabetes Unit Derby Hospitals NHS Foundation Trust Derby DU22 3NE UK

J Diabetes Res. 2014;2014:981721. doi: 10.1155/2014/981721. PubMed

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Adili F, Larijani B, Haghighatpanah M, et al. Diabetic patients: psychological aspects. Annals of the New York Academy of Sciences. 2006;1084:329–349. PubMed

Leppävuori A. Depression and diabetes. Duodecim. 2010;126(5):521–527. PubMed

Lustman PJ, Clouse RE. Depression in diabetic patients: the relationship between mood and glycemic control. Journal of Diabetes and Its Complications. 2005;19(2):113–122. PubMed

Schram MT, Baan CA, Pouwer F. Depression and quality of life in patients with diabetes: a systematic review from the European Depression in Diabetes (EDID) research consortium. Current Diabetes Reviews. 2009;5(2):112–119. PubMed PMC

Campayo A, De Jonge P, Roy JF, et al. Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression. American Journal of Psychiatry. 2010;167(5):580–588. PubMed

Goodridge D, Trepman E, Embil JM. Health-related quality of life in diabetic patients with foot ulcers: literature review. Journal of Wound, Ostomy, and Continence Nursing. 2005;32(6):368–377. PubMed

Christian LM, Graham JE, Padgett DA, Glaser R, Kiecolt-Glaser JK. Stress and wound healing. NeuroImmunoModulation. 2006;13(5-6):337–346. PubMed PMC

Godbout JP, Glaser R. Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer. Journal of Neuroimmune Pharmacology. 2006;1(4):421–427. PubMed

Walburn J, Vedhara K, Hankins M, Rixon L, Weinman J. Psychological stress and wound healing in humans: a systematic review and meta-analysis. Journal of Psychosomatic Research. 2009;67(3):253–271. PubMed

Vileikyte L. Stress and wound healing. Clinics in Dermatology. 2007;25(1):49–55. PubMed

Boulton AJM, Malik RA, Arezzo JC, Sosenko JM. Diabetic somatic neuropathies. Diabetes Care. 2004;27(6):1458–1486. PubMed

Brett CE, Gow AJ, Corley J, Pattie A, Starr JM, Deary IJ. Psychosocial factors and health as determinants of quality of life in community-dwelling older adults. Quality of Life Research. 2012;21(3):505–516. PubMed

Dragomirecká E, Bartoňová J. WHOQoL-Bref, WHOQoL-100. World Health Organization Duality of Life Assessment—Czech Version. 1st edition. Prague, Czech Republic: Psychiatric Center; 2006.

Skevington SM, Mccrate FM. Expecting a good quality of life in health: assessing people with diverse diseases and conditions using the WHOQOL-BREF. Health Expectations. 2012;15(1):49–62. PubMed PMC

Wancata J, Alexandrowicz R, Marquart B, Weiss M, Friedrich F. The criterion validity of the geriatric depression scale: a systematic review. Acta Psychiatrica Scandinavica. 2006;114(6):398–410. PubMed

Yesavage JA, Brink TL, Rose TL. Development and validation of a geriatric depression screening scale: A Preliminary Report. Journal of Psychiatric Research. 1982;17(1):37–49. PubMed

Harkless LB, DeLellis S, Carnegie DH, Burke TJ. Improved foot sensitivity and pain reduction in patients with peripheral neuropathy after treatment with monochromatic infrared photo energy—MIRE. Journal of Diabetes and Its Complications. 2006;20(2):81–87. PubMed

Čatipović-Veselica K. Bortner type a scores and basic emotions: aggression, distrustful, depression, and gregarious. Psychological Reports. 2003;93(1):132–134. PubMed

Lee H, Wilbur J, Kim MJ, Miller AM. Psychosocial risk factors for work-related musculoskeletal disorders of the lower-back among long-haul international female flight attendants. Journal of Advanced Nursing. 2008;61(5):492–502. PubMed

Fortmann SP, Varady AN. Effects of a community-wide health education program on cardiovascular disease morbidity and mortality: the stanford five-city project. American Journal of Epidemiology. 2000;152(4):316–323. PubMed

Bortner RW. A short rating scale as a potential measure of pattern a behavior. Journal of Chronic Diseases. 1969;22(2):87–91. PubMed

Fickley CE, Lloyd CE, Costacou T, Miller RG, Orchard TJ. Type A Behavior and Risk of All-Cause Mortality, CAD, and CAD-Related Mortality in a type 1 diabetic population: 22 years of follow-up in the Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes Care. 2013;36(10):2974–2980. PubMed PMC

Meenan RF, Mason JH, Anderson JJ, Guccione AA, Kazis LE. AIMS2: the content and properties of a revised and expanded arthritis impact measurement scales health status questionnaire. Arthritis and Rheumatism. 1992;35(1):1–10. PubMed

Peters EJG, Lavery LA, Armstrong DG. Diabetic lower extremity infection: Influence of physical, psychological, and social factors. Journal of Diabetes and Its Complications. 2005;19(2):107–112. PubMed

Herber OR, Schnepp W, Rieger MA. A systematic review on the impact of leg ulceration on patients’ quality of life. Health and Quality of Life Outcomes. 2007;5, article 44 PubMed PMC

Gabbay RA, Kaul S, Ulbrecht J, Scheffler NM, Armstrong DG. Motivational interviewing by podiatric physicians: a method for improving patient self-care of the diabetic foot. Journal of the American Podiatric Medical Association. 2011;101(1):78–84. PubMed

Goodridge D, Trepman E, Sloan J, et al. Quality of life of adults with unhealed and healed diabetic foot ulcers. Foot and Ankle International. 2006;27(4):274–280. PubMed

Iversen MM, Midthjell K, Tell GS, et al. The association between history of diabetic foot ulcer, perceived health and psychological distress: The Nord-Trøndelag Health Study. BMC Endocrine Disorders. 2009;9, article 18 PubMed PMC

Jaksa PJ, Mahoney JL. Quality of life in patients with diabetic foot ulcers: validation of the Cardiff Wound Impact Schedule in a Canadian population. International Wound Journal. 2010;7(6):502–507. PubMed PMC

de Meneses LC, Blanes L, Francescato Veiga D, Carvalho Gomes H, Masako Ferreira L. Health-related quality of life and self-esteem in patients with diabetic foot ulcers: results of a cross-sectional comparative study. Ostomy. 2011;57(3):36–43. PubMed

Willrich A, Pinzur M, McNeil M, Juknelis D, Lavery L. Health related quality of life, cognitive function, and depression in diabetic patients with foot ulcer or amputation. A Preliminary Study. Foot and Ankle International. 2005;26(2):128–134. PubMed

Rubin RR, Ciechanowski P, Egede LE, Lin EHB, Lustman PJ. Recognizing and treating depression in patients with diabetes. Current Diabetes Reports. 2004;4(2):119–125. PubMed

Brod M. Quality of life issues in patients with diabetes and lower extremity ulcers: patients and care givers. Quality of Life Research. 1998;7(4):365–372. PubMed

Walsh SM, Sage RA. Depression and chronic diabetic foot disability: a case report of suicide. Clinics in Podiatric Medicine and Surgery. 2002;19(4):493–508. PubMed

Williams LH, Rutter CM, Katon WJ, et al. Depression and incident diabetic foot ulcers: A Prospective Cohort Study. American Journal of Medicine. 2010;123(8):748–754. PubMed PMC

Carrington AL, Mawdsley SKV, Morley M, Kincey J, Boulton AJM. Psychological status of diabetic people with or without lower limb disability. Diabetes Research and Clinical Practice. 1996;32(1-2):19–25. PubMed

Vileikyte L, Peyrot M, Bundy C, et al. The development and validation of a neuropathy- and foot ulcer-specific quality of life instrument. Diabetes Care. 2003;26(9):2549–2555. PubMed

Microdialysis as a tool for antibiotic assessment in patients with diabetic foot: a review

Effects of a 12-Week Interventional Exercise Programme on Muscle Strength, Mobility and Fitness in Patients With Diabetic Foot in Remission: Results From BIONEDIAN Randomised Controlled Trial

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