Disks Large Homolog 4 Protein [protein PSD-95]

topical
1
Terms

protein 90 asociovaný se synapsemi
protein PSD95
protein SAP-90
protein SAP90

 

Discs Large Homolog 4 Protein
Postsynaptic Density Protein 95
PSD-95 Protein
PSD95 Protein
SAP-90 Protein
SAP90 Protein
Synapse-Associated Protein 90

Persistent link   https://www.medvik.cz/link/D000076122
Definition

A neuronal protein consisting of three PDZ DOMAINS, an SH3 DOMAIN, and a C-terminal guanylate kinase-like region (see MAGUK PROTEINS). It localizes to the POST-SYNAPTIC DENSITY and associates with the cytoplasmic tail of NMDA RECEPTORS and SHAKER POTASSIUM CHANNELS, playing a critical role in NMDA receptor-mediated SYNAPTIC PLASTICITY.

DUI
D000076122 MeSH Browser
CUI
M000632224
Previous indexing
Intracellular Signaling Peptides and Proteins (2005-2017); Membrane Proteins (2005-2017)
History note
2018
Public note
2018

Allowable subheadings

AD
administration & dosage 0
AE
adverse effects 0
AG
agonists 0
AN
analysis 0
AI
antagonists & inhibitors 0
BI
biosynthesis 0
BL
blood 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 0
CL
classification 0
DF
deficiency 0
DE
drug effects 0
EC
economics 0
GE
genetics 0
HI
history 0
IM
immunology 0
IP
isolation & purification 0
ME
metabolism 1
PK
pharmacokinetics 0
PD
pharmacology 0
PH
physiology 0
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 0
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.650 Phosphotransferases (Phosphate Group Acceptor) 1
D08.811.913.696.650.450 Guanylate Kinases 3
D08.811.913.696.650.450.500 Discs Large Homolog 1 Protein
D08.811.913.696.650.450.750 Disks Large Homolog 4 Protein 1
D12 Amino Acids, Peptides, and Proteins 16
D12.644 Peptides 1 380
D12.644.360 Intracellular Signaling Peptides and Proteins 174
D12.644.360.011 Activating Transcription Factor 6 3
D12.644.360.024 Adaptor Proteins, Signal Transducing 176
D12.644.360.075 Apoptosis Regulatory Proteins 78
D12.644.360.087 Calcineurin 76
D12.644.360.138 Circadian Rhythm Signaling Peptides and Proteins 11
D12.644.360.175 Cold Shock Proteins and Peptides 3
D12.644.360.225 Cyclin-Dependent Kinase Inhibitor Proteins 42
D12.644.360.262 Cyclins 112
D12.644.360.265 Disks Large Homolog 4 Protein 1
D12.644.360.325 GTP-Binding Protein Regulators 16
D12.644.360.365 I-kappa B Proteins 5
D12.644.360.368 Inhibitor of Growth Protein 1
D12.644.360.372 Intracellular Calcium-Sensing Proteins 2
D12.644.360.410 Mesothelin 2
D12.644.360.420 Methyl-Accepting Chemotaxis Proteins
D12.644.360.534 Mucin-4 5
D12.644.360.537 Myristoylated Alanine-Rich C Kinase Substrate
D12.644.360.539 NLR Proteins 4
D12.644.360.543 Olfactory Marker Protein
D12.644.360.562 Phosphatidylethanolamine Binding Protein
D12.644.360.606 Protein Phosphatase Inhibitory Proteins
D12.644.360.650 RNA-Binding Protein EWS 15
D12.644.360.700 SAP90-PSD95 Associated Proteins
D12.644.360.813 Secreted Frizzled-Related Proteins
D12.644.360.925 Tuberous Sclerosis Complex 1 Protein 7
D12.644.360.938 Tuberous Sclerosis Complex 2 Protein 9
D12.644.360.950 Tumor Necrosis Factor alpha-Induced Protein 3 1
D12.644.360.963 Tumor Protein, Translationally-Controlled 1
D12.776 Proteins 2 575
D12.776.476 Intracellular Signaling Peptides and Proteins 174
D12.776.476.008 3',5'-Cyclic-AMP Phosphodiesterases 12
D12.776.476.009 3',5'-Cyclic-GMP Phosphodiesterases 2
D12.776.476.011 Activating Transcription Factor 6 3
D12.776.476.024 Adaptor Proteins, Signal Transducing 176
D12.776.476.050 Adenylyl Cyclases 160
D12.776.476.075 Apoptosis Regulatory Proteins 78
D12.776.476.081 Axin Signaling Complex 1
D12.776.476.156 Circadian Rhythm Signaling Peptides and Proteins 11
D12.776.476.175 Cold Shock Proteins and Peptides 3
D12.776.476.225 Cyclin-Dependent Kinase Inhibitor Proteins 42
D12.776.476.262 Cyclins 112
D12.776.476.265 Disks Large Homolog 4 Protein 1
D12.776.476.325 GTP-Binding Protein Regulators 16
D12.776.476.338 GTP-Binding Proteins 117
D12.776.476.350 Guanylate Cyclase 29
D12.776.476.381 I-kappa B Proteins 5
D12.776.476.383 Inhibitor of Growth Protein 1
D12.776.476.387 Intracellular Calcium-Sensing Proteins 2
D12.776.476.410 Mesothelin 2
D12.776.476.420 Methyl-Accepting Chemotaxis Proteins
D12.776.476.445 Mitogen-Activated Protein Kinase Phosphatases 1
D12.776.476.534 Mucin-4 5
D12.776.476.539 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.476.543 Olfactory Marker Protein
D12.776.476.555 Phosphatidylethanolamine Binding Protein
D12.776.476.556 Phosphatidylinositol 3-Kinases 120
D12.776.476.557 Phosphoinositide Phospholipase C 2
D12.776.476.559 Phosphoprotein Phosphatases 23
D12.776.476.561 Protein Phosphatase Inhibitory Proteins
D12.776.476.563 Protein Serine-Threonine Kinases 271
D12.776.476.564 Protein Tyrosine Phosphatases 27
D12.776.476.568 Protein-Tyrosine Kinases 620
D12.776.476.590 PTEN Phosphohydrolase 49
D12.776.476.650 RNA-Binding Protein EWS 15
D12.776.476.700 SAP90-PSD95 Associated Proteins
D12.776.476.800 Secreted Frizzled-Related Proteins
D12.776.476.900 Sirtuins 20
D12.776.476.932 Tuberous Sclerosis Complex 1 Protein 7
D12.776.476.935 Tuberous Sclerosis Complex 2 Protein 9
D12.776.476.938 Tumor Necrosis Factor alpha-Induced Protein 3 1
D12.776.476.941 Tumor Protein, Translationally-Controlled 1
D12.776.543 Membrane Proteins 849
D12.776.543.019 5-Lipoxygenase-Activating Proteins 1
D12.776.543.029 Amphiregulin 3
D12.776.543.039 Amyloid beta-Protein Precursor 58
D12.776.543.080 Ankyrins 10
D12.776.543.090 Arrestins 6
D12.776.543.095 B7 Antigens 3
D12.776.543.100 Bacterial Outer Membrane Proteins 92
D12.776.543.116 Bcl-2-Like Protein 11 5
D12.776.543.131 Cadherin Related Proteins 1
D12.776.543.162 Calnexin 4
D12.776.543.178 Carbonic Anhydrase IX 19
D12.776.543.193 Chemokine CX3CL1 3
D12.776.543.200 Cornified Envelope Proline-Rich Proteins 2
D12.776.543.213 Discs Large Homolog 1 Protein
D12.776.543.219 Disks Large Homolog 4 Protein 1
D12.776.543.225 Dysferlin
D12.776.543.250 Dystrophin 46
D12.776.543.268 Dystrophin-Associated Proteins
D12.776.543.277 Electron Transport Chain Complex Proteins 31
D12.776.543.287 Ephrins 1
D12.776.543.306 gp100 Melanoma Antigen 1
D12.776.543.325 Heterotrimeric GTP-Binding Proteins 14
D12.776.543.475 LDL-Receptor Related Protein-Associated Protein
D12.776.543.484 Lipid-Linked Proteins 1
D12.776.543.488 MARVEL Domain-Containing Proteins 1
D12.776.543.493 Matrix Metalloproteinases, Membrane-Associated 1
D12.776.543.512 Membrane Fusion Proteins
D12.776.543.550 Membrane Glycoproteins 200
D12.776.543.585 Membrane Transport Proteins 207
D12.776.543.602 Mitochondrial Trifunctional Protein 2
D12.776.543.620 Myelin Proteins 32
D12.776.543.637 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.543.653 NADPH Oxidases 44
D12.776.543.685 Neurofibromin 2 3
D12.776.543.689 Peroxisomal Biogenesis Factor 2
D12.776.543.693 Phospholipid Transfer Proteins 6
D12.776.543.695 Pore Forming Cytotoxic Proteins 8
D12.776.543.696 Presenilins 6
D12.776.543.697 Protoporphyrinogen Oxidase 5
D12.776.543.701 Pulmonary Surfactant-Associated Protein B 4
D12.776.543.717 Pulmonary Surfactant-Associated Protein C 5
D12.776.543.725 Receptor Activity-Modifying Proteins 1
D12.776.543.733 Receptor-Like Protein Tyrosine Phosphatases
D12.776.543.750 Receptors, Cell Surface 511
D12.776.543.800 Serrate-Jagged Proteins 1
D12.776.543.850 Spectrin 20
D12.776.543.875 Stromal Interaction Molecules 3
D12.776.543.900 Tetraspanins 13
D12.776.543.930 Thylakoid Membrane Proteins 1
D12.776.543.935 Thyroid Hormone-Binding Proteins
D12.776.543.940 Tight Junction Proteins 5
D12.776.543.985 Utrophin 1
D12.776.543.990 Vesicular Transport Proteins 45
D12.776.631 Nerve Tissue Proteins 263
D12.776.631.024 Acid Sensing Ion Channels 2
D12.776.631.050 Agrin
D12.776.631.069 Ataxins 2
D12.776.631.087 Calbindin 1
D12.776.631.124 Chimerin Proteins 2
D12.776.631.199 Chromogranins 25
D12.776.631.212 Collapsin Response Mediator Protein 1
D12.776.631.224 Disks Large Homolog 4 Protein 1
D12.776.631.249 Dopamine and cAMP-Regulated Phosphoprotein 32 3
D12.776.631.262 Dysbindin
D12.776.631.274 Fatty Acid-Binding Protein 7 1
D12.776.631.299 Fragile X Mental Retardation Protein 7
D12.776.631.400 GAP-43 Protein 5
D12.776.631.480 Glucose Transporter Type 3
D12.776.631.520 ELAV Proteins 2
D12.776.631.530 Homeobox Protein SIX3
D12.776.631.540 Metallothionein 3 1
D12.776.631.560 Microtubule-Associated Proteins 101
D12.776.631.580 Myelin Proteins 32
D12.776.631.590 Natriuretic Peptide, Brain 346
D12.776.631.600 Nerve Growth Factors 70
D12.776.631.607 Nestin 17
D12.776.631.609 Neurexins
D12.776.631.611 Neuro-Oncological Ventral Antigen
D12.776.631.615 Neuroendocrine Secretory Protein 7B2
D12.776.631.630 Neurofilament Proteins 51
D12.776.631.635 Neuroglobin
D12.776.631.640 Neurogranin 1
D12.776.631.641 Neuroligins
D12.776.631.642 Neuronal Apoptosis-Inhibitory Protein
D12.776.631.645 Neuronal Calcium-Sensor Proteins 1
D12.776.631.650 Neuropeptides 202
D12.776.631.651 Nogo Receptors
D12.776.631.653 Olfactory Marker Protein
D12.776.631.654 Oligodendrocyte Transcription Factor 2
D12.776.631.656 Rabphilin-3A
D12.776.631.658 S100 Proteins 133
D12.776.631.703 SAP90-PSD95 Associated Proteins
D12.776.631.727 Slit Homolog 2 Protein
D12.776.631.750 Synapsins 2
D12.776.631.775 Synaptogyrins 1
D12.776.631.800 Synaptophysin 10
D12.776.631.860 Synucleins 3
D12.776.631.920 Tubulin 160
D12.776.631.960 Voltage-Gated Sodium Channels 6

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