Centromere Protein A [protein CENP-A]

topical
2
Terms

centromerový protein A
centromérový protein A

 

CENP-A Protein
CENPA Protein
Centromere Autoantigens 17K
Centromere Protein 17K

Persistent link   https://www.medvik.cz/link/D000076247
Definition

A 17 kDa, centromeric, poly(ADP)-ribose binding protein that is structurally similar to HISTONE H3 and localizes to NUCLEOSOMES within the CENTROMERE; specifically within the region that binds KINETOCHORES, where it replaces histone H3. It plays a critical role in recruiting kinetochore proteins and progression through MITOSIS, chromosome segregation, and CYTOKINESIS. It also binds sera from patients with some scleroderma-like AUTOIMMUNE DISEASES.

DUI
D000076247 MeSH Browser
CUI
M0147022
History note
2018 (1987)
Public note
2018; CENTROMERE PROTEIN A was indexed under AUTOANTIGENS 1987-2017 and CHROMOSOMAL PROTEINS, NON-HISTONE 1990-2017; and under NUCLEOPROTEINS 1987-1989

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 1
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 579
D12.776.157 Carrier Proteins 546
D12.776.157.687 Poly-ADP-Ribose Binding Proteins 5
D12.776.157.687.063 Apoptosis Inducing Factor 10
D12.776.157.687.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.157.687.157 CCCTC-Binding Factor 2
D12.776.157.687.173 Centromere Protein A 2
D12.776.157.687.188 Centromere Protein B
D12.776.157.687.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.157.687.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.157.687.375 DNA Topoisomerases, Type I 24
D12.776.157.687.438 DNA-Activated Protein Kinase 14
D12.776.157.687.450 Heat Shock Transcription Factors 1
D12.776.157.687.462 Heterogeneous Nuclear Ribonucleoprotein A1
D12.776.157.687.485 Histones 371
D12.776.157.687.493 Ku Autoantigen 5
D12.776.157.687.495 MRE11 Homologue Protein 8
D12.776.157.687.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.157.687.497 NF-kappa B p52 Subunit 2
D12.776.157.687.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.157.687.575 Nitric Oxide Synthase Type II 75
D12.776.157.687.613 Telomerase 193
D12.776.157.687.650 Tumor Suppressor Protein p53 762
D12.776.157.687.750 Werner Syndrome Helicase 2
D12.776.157.687.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.157.687.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.260 DNA-Binding Proteins 561
D12.776.260.060 Adenovirus E2 Proteins 1
D12.776.260.103 Basic Helix-Loop-Helix Transcription Factors 63
D12.776.260.108 Basic-Leucine Zipper Transcription Factors 18
D12.776.260.114 Butyrate Response Factor 1
D12.776.260.120 CCCTC-Binding Factor 2
D12.776.260.123 Centromere Protein A 2
D12.776.260.125 Centromere Protein B
D12.776.260.158 Early Growth Response Transcription Factors 1
D12.776.260.197 Elongin
D12.776.260.235 Erythroid-Specific DNA-Binding Factors 1
D12.776.260.246 Factor For Inversion Stimulation Protein
D12.776.260.254 G-Box Binding Factors
D12.776.260.257 GATA Transcription Factors 2
D12.776.260.260 Heat Shock Transcription Factors 1
D12.776.260.262 Hepatocyte Nuclear Factors 5
D12.776.260.268 Heterogeneous-Nuclear Ribonucleoprotein K
D12.776.260.312 HMGA Proteins 1
D12.776.260.356 HMGB Proteins 4
D12.776.260.400 Homeodomain Proteins 125
D12.776.260.420 I-kappa B Proteins 5
D12.776.260.457 Immunoglobulin J Recombination Signal Sequence-Binding Protein
D12.776.260.495 Integration Host Factors
D12.776.260.504 Interferon Regulatory Factors 11
D12.776.260.513 Interferon-Stimulated Gene Factor 3
D12.776.260.522 Kruppel-Like Transcription Factors 26
D12.776.260.525 Ku Autoantigen 5
D12.776.260.527 Leucine-Responsive Regulatory Protein
D12.776.260.529 LIM-Homeodomain Proteins 5
D12.776.260.531 Liver X Receptors 5
D12.776.260.532 Matrix Attachment Region Binding Proteins 9
D12.776.260.534 MDS1 and EVI1 Complex Locus Protein 2
D12.776.260.536 Methyl-CpG-Binding Protein 2 12
D12.776.260.538 Minichromosome Maintenance 1 Protein 1
D12.776.260.539 MRE11 Homologue Protein 8
D12.776.260.540 MutL Proteins
D12.776.260.556 MutS Proteins
D12.776.260.560 Myeloid-Lymphoid Leukemia Protein 39
D12.776.260.600 NF-kappa B 220
D12.776.260.605 NFI Transcription Factors 8
D12.776.260.615 Nuclear Respiratory Factors
D12.776.260.623 Nucleobindins 3
D12.776.260.630 Oncogene Protein p55(v-myc) 1
D12.776.260.640 Origin Recognition Complex 1
D12.776.260.643 Orphan Nuclear Receptors 2
D12.776.260.645 Paired Box Transcription Factors 21
D12.776.260.650 Peptidyl-Prolyl Cis-Trans Isomerase NIMA-Interacting 4
D12.776.260.655 POU Domain Factors 4
D12.776.260.660 Proto-Oncogene Proteins c-bcl-6 3
D12.776.260.665 Proto-Oncogene Proteins c-ets 19
D12.776.260.675 Proto-Oncogene Proteins c-myb 30
D12.776.260.682 Proto-Oncogene Proteins c-rel 2
D12.776.260.690 Proto-Oncogene Proteins c-sis 3
D12.776.260.693 PTB-Associated Splicing Factor
D12.776.260.695 Rad51 Recombinase 42
D12.776.260.696 Rad52 DNA Repair and Recombination Protein 9
D12.776.260.700 Replication Protein A 12
D12.776.260.702 Replication Protein C 3
D12.776.260.703 Repressor Proteins 189
D12.776.260.704 Retinoblastoma Protein 52
D12.776.260.713 Smad Proteins 14
D12.776.260.716 SMARCB1 Protein 15
D12.776.260.719 SOX Transcription Factors 1
D12.776.260.725 T-Box Domain Proteins 14
D12.776.260.730 TCF Transcription Factors 3
D12.776.260.733 TEA Domain Transcription Factors 3
D12.776.260.735 Telomere-Binding Proteins 24
D12.776.260.750 Toll-Like Receptor 9 16
D12.776.260.755 Trans-Activators 110
D12.776.260.760 Transcription Factor AP-2 1
D12.776.260.768 Transcription Factor MTF-1
D12.776.260.775 Transcription Factors, General 1
D12.776.260.790 Tristetraprolin 2
D12.776.260.805 Tumor Suppressor p53-Binding Protein 1 16
D12.776.260.820 Tumor Suppressor Protein p53 762
D12.776.260.885 Tumor Protein p73 6
D12.776.260.950 Winged-Helix Transcription Factors
D12.776.260.963 X-ray Repair Cross Complementing Protein 1 9
D12.776.260.975 Xeroderma Pigmentosum Group A Protein 2
D12.776.660 Nuclear Proteins 455
D12.776.660.235 Chromosomal Proteins, Non-Histone 93
D12.776.660.235.025 Bromodomain Containing Proteins 3
D12.776.660.235.050 CCCTC-Binding Factor 2
D12.776.660.235.100 Centromere Protein A 2
D12.776.660.235.199 Centromere Protein B
D12.776.660.235.300 Chromobox Protein Homolog 5
D12.776.660.235.350 Cohesins
D12.776.660.235.400 High Mobility Group Proteins 20
D12.776.660.235.500 Minichromosome Maintenance Proteins 4
D12.776.660.235.550 Methyl-CpG-Binding Protein 2 12
D12.776.660.235.600 Polycomb-Group Proteins 7
D12.776.660.235.650 SMARCB1 Protein 15
D12.776.660.235.675 Structural Maintenance of Chromosome Protein 1
D12.776.660.235.700 Telomere-Binding Proteins 24
D12.776.660.235.850 Tumor Suppressor p53-Binding Protein 1 16
D12.776.660.720 Poly-ADP-Ribose Binding Proteins 5
D12.776.660.720.063 Apoptosis Inducing Factor 10
D12.776.660.720.125 Ataxia Telangiectasia Mutated Proteins 89
D12.776.660.720.157 CCCTC-Binding Factor 2
D12.776.660.720.173 Centromere Protein A 2
D12.776.660.720.188 Centromere Protein B
D12.776.660.720.250 Cyclin-Dependent Kinase Inhibitor p21 74
D12.776.660.720.313 DNA (Cytosine-5-)-Methyltransferase 1 7
D12.776.660.720.375 DNA Topoisomerases, Type I 24
D12.776.660.720.438 DNA-Activated Protein Kinase 14
D12.776.660.720.462 Heat Shock Transcription Factors 1
D12.776.660.720.485 Histones 371
D12.776.660.720.493 Ku Autoantigen 5
D12.776.660.720.495 MRE11 Homologue Protein 8
D12.776.660.720.496 Myristoylated Alanine-Rich C Kinase Substrate
D12.776.660.720.497 NF-kappa B p52 Subunit 2
D12.776.660.720.499 Nicotinamide-Nucleotide Adenylyltransferase 3
D12.776.660.720.575 Nitric Oxide Synthase Type II 75
D12.776.660.720.613 Telomerase 193
D12.776.660.720.650 Tumor Suppressor Protein p53 762
D12.776.660.720.750 Werner Syndrome Helicase 2
D12.776.660.720.813 X-ray Repair Cross Complementing Protein 1 9
D12.776.660.720.875 Xeroderma Pigmentosum Group A Protein 2
D12.776.664 Nucleoproteins 91
D12.776.664.235 Chromosomal Proteins, Non-Histone 93
D12.776.664.235.025 Bromodomain Containing Proteins 3
D12.776.664.235.050 CCCTC-Binding Factor 2
D12.776.664.235.100 Centromere Protein A 2
D12.776.664.235.199 Centromere Protein B
D12.776.664.235.300 Chromobox Protein Homolog 5
D12.776.664.235.350 Cohesins
D12.776.664.235.400 High Mobility Group Proteins 20
D12.776.664.235.700 Methyl-CpG-Binding Protein 2 12
D12.776.664.235.750 Minichromosome Maintenance Proteins 4
D12.776.664.235.800 Polycomb-Group Proteins 7
D12.776.664.235.900 SMARCB1 Protein 15
D12.776.664.235.925 Structural Maintenance of Chromosome Protein 1
D12.776.664.235.950 Tumor Suppressor p53-Binding Protein 1 16
D23 Biological Factors 143
D23.050 Antigens 1 131
D23.050.422 Autoantigens 118
D23.050.422.031 Centromere Protein A 2
D23.050.422.061 Centromere Protein B
D23.050.422.093 Collagen Type XVII
D23.050.422.124 Desmoglein 1 1
D23.050.422.249 Desmoglein 3 4
D23.050.422.500 Heymann Nephritis Antigenic Complex
D23.050.422.625 Myelin-Oligodendrocyte Glycoprotein 14
D23.050.422.750 snRNP Core Proteins 1
D23.050.422.875 SS-B Antigen

CENPA protein, human Chemical MeSH Browser

Cenpa protein, mouse Chemical MeSH Browser

Cid protein, Drosophila Chemical MeSH Browser

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