Fibrinogen [fibrinogen]
- Terms
-
faktor I
koagulační faktor I
-
Blood Coagulation Factor I
Coagulation Factor I
Factor I
gamma-Fibrinogen
Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.
- Annotation
- a blood coag factor: do not confuse entry term FACTOR I with COMPLEMENT FACTOR I
- DUI
- D005340 MeSH Browser
- CUI
- M0008430
- CAS
- Fibrinogens
Combination
- deficiency
- Afibrinogenemia
Allowable subheadings
- AD
- administration & dosage 39
- AE
- adverse effects 9
- AG
- agonists 0
- AA
- analogs & derivatives 2
- AN
- analysis 69
- AI
- antagonists & inhibitors 2
- BI
- biosynthesis 9
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 25
- CL
- classification 1
- DE
- drug effects 7
- EC
- economics 1
- GE
- genetics 24
- HI
- history 0
- IM
- immunology 8
- IP
- isolation & purification 6
- ME
- metabolism 58
- PK
- pharmacokinetics 0
- PD
- pharmacology 7
- PH
- physiology 25
- PO
- poisoning 0
- RE
- radiation effects 1
- ST
- standards 3
- SD
- supply & distribution 0
- TU
- therapeutic use 98
- TO
- toxicity 0
- UL
- ultrastructure 3
- UR
- urine 2