Heavy Chain Disease [nemoc z těžkých řetězců]
- Terms
-
Franklinova nemoc
gama HCD
mí HCD
nemoc těžkých řetězců
nemoc z těžkých řetězců gama
nemoc z těžkých řetězců mí
onemocnění těžkých řetězců
-
Franklin Disease
Franklin's Disease
gamma-Chain Disease
mu-Chain Disease
A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.
- Annotation
- specify the immunoglobulin fragment coord NIM, as gamma chain dis = HEAVY CHAIN DISEASE (IM) + IMMUNOGLOBULIN GAMMA-CHAINS (NIM); ALPHA-CHAIN DISEASE see IMMUNOPROLIFERATIVE SMALL INTESTINAL DISEASE is available
- DUI
- D006362 MeSH Browser
- CUI
- M0009991
- History note
- 66(64)
- Public note
- 66
Allowable subheadings
- BL
- blood 1
- CF
- cerebrospinal fluid
- CI
- chemically induced 1
- CL
- classification
- CO
- complications 1
- CN
- congenital
- DI
- diagnosis 2
- DG
- diagnostic imaging
- DH
- diet therapy
- DT
- drug therapy 2
- EC
- economics
- EM
- embryology
- EN
- enzymology
- EP
- epidemiology
- EH
- ethnology
- ET
- etiology 2
- GE
- genetics 1
- HI
- history
- IM
- immunology 2
- ME
- metabolism
- MI
- microbiology
- MO
- mortality
- NU
- nursing
- PS
- parasitology
- PA
- pathology 2
- PP
- physiopathology
- PC
- prevention & control
- PX
- psychology
- RT
- radiotherapy
- RH
- rehabilitation
- SU
- surgery
- TH
- therapy
- UR
- urine
- VE
- veterinary
- VI
- virology
CHA heavy chain disease protein, human Chemical MeSH Browser
FOR heavy chain disease protein, human Chemical MeSH Browser
IGHM protein, human Chemical MeSH Browser
RIV immunoglobulin variant protein, human Chemical MeSH Browser
Wis heavy-chain disease protein, human Chemical MeSH Browser
heavy chain disease proteins, human Chemical MeSH Browser