Hydroxymethylglutaryl CoA Reductases [hydroxymethylglutaryl-CoA-reduktasy]

topical
84
Terms

3-HMG-CoA-reduktázy
HMG-CoA-reduktasa
HMG-CoA-reduktasy
HMG-CoA-reduktáza
HMG-CoA-reduktázy

 

3-Hydroxy-3-methylglutaryl CoA Reductase
HMG CoA Reductase
HMG CoA Reductases
Hydroxymethylglutaryl CoA Reductase

Persistent link   https://www.medvik.cz/link/D006903
Definition

Enzymes that catalyze the reversible reduction of alpha-carboxyl group of 3-hydroxy-3-methylglutaryl-coenzyme A to yield MEVALONIC ACID.

DUI
D006903 MeSH Browser
CUI
M0010772
Previous indexing
Alcohol Oxidoreductases (1966-1977); Glutarates (1966-1974); Mevalonic Acid (1966-1974)
History note
78(75); was see under ALCOHOL OXIDOREDUCTASES 1975-77
Public note
78; was see under ALCOHOL OXIDOREDUCTASES 1975-77

Combination

antagonists & inhibitors
Hydroxymethylglutaryl-CoA Reductase Inhibitors

Allowable subheadings

AD
administration & dosage 14
AE
adverse effects 9
AN
analysis
BI
biosynthesis
BL
blood 1
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 2
CL
classification
DF
deficiency
DE
drug effects 7
EC
economics
GE
genetics 5
HI
history
IM
immunology 8
IP
isolation & purification
ME
metabolism 10
PK
pharmacokinetics 3
PD
pharmacology 14
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 30
TO
toxicity 1
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 189
D04 Polycyclic Compounds 65
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 547
D08.811.682 Oxidoreductases 446
D08.811.682.047 Alcohol Oxidoreductases 97
D08.811.682.047.820 NAD (+) and NADP (+) Dependent Alcohol Oxidoreductases
D08.811.682.047.820.150 3-Hydroxyacyl CoA Dehydrogenases 15
D08.811.682.047.820.150.207 3-Hydroxyacyl-CoA Dehydrogenase
D08.811.682.047.820.150.415 Hydroxymethylglutaryl CoA Reductases 84
D08.811.682.047.820.150.415.250 Hydroxymethylglutaryl-CoA Reductases, NAD-Dependent
D08.811.682.047.820.150.415.750 Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent
D08.811.682.047.820.150.707 Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase 2
D08.811.682.047.820.150.926 Peroxisomal Multifunctional Protein-2
D09 Carbohydrates 723
D10 Lipids 2 524
D12 Amino Acids, Peptides, and Proteins 16
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 110
D26 Pharmaceutical Preparations 7 034
D27 Chemical Actions and Uses 374

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