Prions [priony]
- Terms
-
prionové proteiny
proteiny PrP
virus encefalopatie norků
-
Mink Encephalopathy Virus
Prion
Small proteinaceous infectious particles which resist inactivation by procedures that modify NUCLEIC ACIDS and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME; GERSTMANN-STRAUSSLER SYNDROME; and INSOMNIA, FATAL FAMILIAL.
- DUI
- D011328 MeSH Browser
- CUI
- M0017586
- Previous indexing
- Viral Proteins (1966-1985); PrPSc Proteins (1966-1985)
- History note
- 86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
- Online note
- use PRIONS to search MINK ENCEPHALOPATHY VIRUS & TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK 1975-92
- Public note
- 86; MINK ENCEPHALOPATHY VIRUS was heading 1991-92, was see under VERTEBRATE VIRUSES, UNCLASSIFIED (now VIRUSES, UNCLASSIFIED) 1975-90; TRANSMISSIBLE ENCEPHALOPATHY VIRUS OF MINK was see MINK ENCEPHALOPATHY VIRUS 1975-92
Allowable subheadings
- AD
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- AE
- adverse effects 11
- AG
- agonists 0
- AN
- analysis 22
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis 0
- BL
- blood 8
- CF
- cerebrospinal fluid 1
- CS
- chemical synthesis 2
- CH
- chemistry 22
- CL
- classification 2
- DE
- drug effects 3
- EC
- economics 0
- GE
- genetics 33
- HI
- history 3
- IM
- immunology 1
- IP
- isolation & purification 5
- ME
- metabolism 18
- PY
- pathogenicity 22
- PK
- pharmacokinetics 0
- PD
- pharmacology 0
- PH
- physiology 17
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
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- TU
- therapeutic use 1
- TO
- toxicity 1
- UL
- ultrastructure 3
- UR
- urine 0