Prothrombin [protrombin]

topical
116
Terms

faktor II
koagulační faktor II
krevní koagulační faktor II
prothrombin

 

Blood Coagulation Factor II
Coagulation Factor II
Differentiation Reversal Factor
Factor II

Persistent link   https://www.medvik.cz/link/D011516
Definition

A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.

Annotation
a blood coag factor; an enzyme precursor
DUI
D011516 MeSH Browser
CUI
M0017904
CAS
Blood-coagulation factor II

Combination

deficiency
Hypoprothrombinemias

Allowable subheadings

AD
administration & dosage 9
AE
adverse effects
AG
agonists
AA
analogs & derivatives
AN
analysis 9
AI
antagonists & inhibitors 4
BI
biosynthesis 1
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DE
drug effects 2
EC
economics
GE
genetics 25
HI
history
IM
immunology 2
IP
isolation & purification 2
ME
metabolism 3
PK
pharmacokinetics
PD
pharmacology 4
PH
physiology 3
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 18
TO
toxicity
UL
ultrastructure 1
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.622 Enzyme Precursors 68
D08.622.184 Chymotrypsinogen 5
D08.622.200 Complement Factor B 3
D08.622.355 Factor IX 82
D08.622.432 Factor VII 55
D08.622.471 Factor X 36
D08.622.490 Factor XI 5
D08.622.500 Factor XII 18
D08.622.505 Factor XIII 14
D08.622.509 Pepsinogens 16
D08.622.610 Plasminogen 43
D08.622.658 Prekallikrein 6
D08.622.705 Protein C 111
D08.622.709 Prothrombin 116
D08.622.885 Trypsinogen 22
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 579
D12.776.124 Blood Proteins 909
D12.776.124.125 Blood Coagulation Factors 332
D12.776.124.125.050 beta-Thromboglobulin 7
D12.776.124.125.300 Factor V 94
D12.776.124.125.325 Factor VII 55
D12.776.124.125.350 Factor VIII 311
D12.776.124.125.375 Factor IX 82
D12.776.124.125.400 Factor X 36
D12.776.124.125.425 Factor XI 5
D12.776.124.125.450 Factor XII 18
D12.776.124.125.475 Factor XIII 14
D12.776.124.125.500 Fibrinogen 485
D12.776.124.125.515 Fibrinopeptide A 9
D12.776.124.125.530 Fibrinopeptide B 6
D12.776.124.125.597 Kallikreins 39
D12.776.124.125.635 Kininogens 7
D12.776.124.125.640 Plasminogen Activator Inhibitor 1 74
D12.776.124.125.645 Plasminogen Activator Inhibitor 2 5
D12.776.124.125.662 Plasminogen Activators 56
D12.776.124.125.691 Platelet Factor 3 4
D12.776.124.125.720 Platelet Factor 4 18
D12.776.124.125.800 Prothrombin 116
D12.776.124.125.890 Thrombin 228
D12.776.124.125.900 Thromboplastin 57
D12.776.124.125.920 von Willebrand Factor 131
D12.776.811 Protein Precursors 132
D12.776.811.243 Enzyme Precursors 68
D12.776.811.243.184 Chymotrypsinogen 5
D12.776.811.243.200 Complement Factor B 3
D12.776.811.243.355 Factor IX 82
D12.776.811.243.432 Factor VII 55
D12.776.811.243.471 Factor X 36
D12.776.811.243.490 Factor XI 5
D12.776.811.243.500 Factor XII 18
D12.776.811.243.505 Factor XIII 14
D12.776.811.243.509 Pepsinogens 16
D12.776.811.243.610 Plasminogen 43
D12.776.811.243.658 Prekallikrein 6
D12.776.811.243.705 Protein C 111
D12.776.811.243.709 Prothrombin 116
D12.776.811.243.885 Trypsinogen 22
D23 Biological Factors 143
D23.119 Blood Coagulation Factors 332
D23.119.050 beta-Thromboglobulin 7
D23.119.100 Calcium 2 832
D23.119.300 Factor V 94
D23.119.325 Factor VII 55
D23.119.350 Factor VIII 311
D23.119.375 Factor IX 82
D23.119.400 Factor X 36
D23.119.425 Factor XI 5
D23.119.450 Factor XII 18
D23.119.475 Factor XIII 14
D23.119.490 Fibrinogen 485
D23.119.500 Fibrinopeptide A 9
D23.119.510 Fibrinopeptide B 6
D23.119.597 Kallikreins 39
D23.119.630 Kininogens 7
D23.119.832 Plasminogen Inactivators 14
D23.119.865 Platelet Activating Factor 32
D23.119.932 Platelet Factor 3 4
D23.119.940 Platelet Factor 4 18
D23.119.945 Prothrombin 116
D23.119.960 Thrombin 228
D23.119.965 Thromboplastin 57
D23.119.970 Tissue Plasminogen Activator 238
D23.119.985 von Willebrand Factor 131

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