Prothrombin [protrombin]
- Terms
-
faktor II
koagulační faktor II
krevní koagulační faktor II
prothrombin
-
Blood Coagulation Factor II
Coagulation Factor II
Differentiation Reversal Factor
Factor II
A plasma protein that is the inactive precursor of thrombin. It is converted to thrombin by a prothrombin activator complex consisting of factor Xa, factor V, phospholipid, and calcium ions. Deficiency of prothrombin leads to hypoprothrombinemia.
- Annotation
- a blood coag factor; an enzyme precursor
- DUI
- D011516 MeSH Browser
- CUI
- M0017904
- CAS
- Blood-coagulation factor II
Combination
- deficiency
- Hypoprothrombinemias
Allowable subheadings
- AD
- administration & dosage 9
- AE
- adverse effects 0
- AG
- agonists 0
- AA
- analogs & derivatives 0
- AN
- analysis 9
- AI
- antagonists & inhibitors 4
- BI
- biosynthesis 1
- CF
- cerebrospinal fluid 0
- CS
- chemical synthesis 0
- CH
- chemistry 1
- CL
- classification 0
- DE
- drug effects 2
- EC
- economics 0
- GE
- genetics 24
- HI
- history 0
- IM
- immunology 2
- IP
- isolation & purification 2
- ME
- metabolism 3
- PK
- pharmacokinetics 0
- PD
- pharmacology 4
- PH
- physiology 3
- PO
- poisoning 0
- RE
- radiation effects 0
- ST
- standards 0
- SD
- supply & distribution 0
- TU
- therapeutic use 18
- TO
- toxicity 0
- UL
- ultrastructure 1
- UR
- urine 0