CD40 Antigens [antigeny CD40]
- Terms
 - 
            
antigen CD40
CD40 antigen
CD40 antigeny 
- 
            
Antigens, CD40
CD40 Antigen
CDw40 Antigen
TNFRSF5 Receptor
Tumor Necrosis Factor Receptor Superfamily, Member 5 
Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
- DUI
 - D019013 MeSH Browser
 - CUI
 - M0028391
 - Previous indexing
 - Antigens, CD (1990-1995); Antigens, Differentiation, B-Lymphocyte (1988-1995)
 - History note
 - 2018 (1988)
 - Public note
 - 2018; see ANTIGENS, CD40 1996-2017, CD40 ANTIGEN 1989-95, and CDW40 ANTIGEN 1988-95; CD40 ANTIGEN was indexed under ANTIGENS, CD 1990-95; and under ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1989-95; CDW40 ANTIGEN was indexed under ANTIGENS, CD 1990-95; and under ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1988-95
 
Allowable subheadings
- AD
 - administration & dosage
 - AG
 - agonists
 - AN
 - analysis 2
 - AI
 - antagonists & inhibitors 3
 - BI
 - biosynthesis 1
 - BL
 - blood 1
 - CH
 - chemistry
 - CL
 - classification
 - DF
 - deficiency
 - DE
 - drug effects
 - GE
 - genetics 2
 - HI
 - history
 - IM
 - immunology 5
 - IP
 - isolation & purification
 - ME
 - metabolism 4
 - PH
 - physiology 2
 - RE
 - radiation effects
 - TU
 - therapeutic use
 - UL
 - ultrastructure