Core Binding Factor Alpha 2 Subunit [protein PEBP2A2]

topical
27
Terms

protein AML1A
protein AML1B
protein AML1C
protein AML1D

 

Acute Myeloid Leukemia 1 Protein
Acute Myeloid Leukemia 1A Protein
Acute Myeloid Leukemia 1B Protein
Acute Myeloid Leukemia 1C Protein
Acute Myeloid Leukemia 1D Protein
AML1A Protein
AML1B Protein
AML1C Protein
AML1D Protein
Core-Binding Factor Alpha 2 Protein
Pebp2a2 Protein
Runt-Related Transcription Factor 1
Runx1 Protein

Persistent link   https://www.medvik.cz/link/D050676
Definition

A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.

DUI
D050676 MeSH Browser
CUI
M0215816
Previous indexing
DNA-Binding Proteins (1996-2005); Neoplasm Proteins (1993-1996); Proto-Oncogene Proteins (1996-2005); Transcription Factors (1996-2005)
History note
2006(1993)
Public note
2006; RUNX1 PROTEIN was indexed under DNA-BINDING PROTEINS 1996-2005, NEOPLASM PROTEINS 1993-1996, PROTO-ONCOGENE PROTEINS 1996-2005, & TRANSCRIPTION FACTORS 1996-2005

Allowable subheadings

AD
administration & dosage
AE
adverse effects 1
AG
agonists
AN
analysis 2
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood 1
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 1
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics 16
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 1
PK
pharmacokinetics
PD
pharmacology
PH
physiology 2
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D01 Inorganic Chemicals 68
D02 Organic Chemicals 391
D03 Heterocyclic Compounds 192
D04 Polycyclic Compounds 66
D05 Macromolecular Substances 103
D06 Hormones, Hormone Substitutes, and Hormone Antagonists 43
D08 Enzymes and Coenzymes 7
D09 Carbohydrates 724
D10 Lipids 2 535
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 587
D12.776.930 Transcription Factors 736
D12.776.930.155 Core Binding Factors 3
D12.776.930.155.200 Core Binding Factor alpha Subunits 1
D12.776.930.155.200.100 Core Binding Factor Alpha 1 Subunit 6
D12.776.930.155.200.200 Core Binding Factor Alpha 2 Subunit 27
D12.776.930.155.200.300 Core Binding Factor Alpha 3 Subunit 1
D13 Nucleic Acids, Nucleotides, and Nucleosides 9
D20 Complex Mixtures 19
D23 Biological Factors 143
D25 Biomedical and Dental Materials 111
D26 Pharmaceutical Preparations 7 071
D27 Chemical Actions and Uses 374

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