Cyclin-Dependent Kinase 4 [cyklin-dependentní kinasa 4]

topical
79
Terms

cyklin-dependentní kináza 4
kinasa p34PSK-J3
kinasa PSK-J3
kináza PSK-J3
protein Cdk4
proteinkinasa Cdk4
proteinkináza Cdk4

 

Cdk4 Cyclin-Dependent Kinase
Cdk4 Protein
Cdk4 Protein Kinase
Cell Division Protein Kinase 4
Cyclin D-Dependent Kinase CDK4
p34PSK-J3 Kinase
PSK-J3 Kinase

Persistent link   https://www.medvik.cz/link/D051358
Definition

Cyclin-dependent kinase 4 is a key regulator of G1 PHASE of the CELL CYCLE. It partners with CYCLIN D to phosphorylate RETINOBLASTOMA PROTEIN. CDK4 activity is inhibited by CYCLIN-DEPENDENT KINASE INHIBITOR P16.

DUI
D051358 MeSH Browser
CUI
M0208277
History note
2006(1992)
Public note
2006; CYCLIN-DEPENDENT KINASE 4 was indexed under CYCLIN-DEPENDENT KINASES & PROTO-ONCOGENE PROTEINS 2005, CELL CYCLE PROTEINS 1992-2004, PROTEIN SERINE THREONINE KINASES 1995, & under PROTEIN KINASES 1992-1994

Allowable subheadings

AD
administration & dosage 3
AE
adverse effects 4
AN
analysis
AI
antagonists & inhibitors 48
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism 7
PK
pharmacokinetics 2
PD
pharmacology 5
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use 18
TO
toxicity
UL
ultrastructure
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.811 Enzymes 1 551
D08.811.913 Transferases 72
D08.811.913.696 Phosphotransferases 69
D08.811.913.696.620 Phosphotransferases (Alcohol Group Acceptor) 32
D08.811.913.696.620.682 Protein Kinases 249
D08.811.913.696.620.682.700 Protein Serine-Threonine Kinases 273
D08.811.913.696.620.682.700.646 Proline-Directed Protein Kinases 1
D08.811.913.696.620.682.700.646.500 Cyclin-Dependent Kinases 231
D08.811.913.696.620.682.700.646.500.500 CDC2-CDC28 Kinases 25
D08.811.913.696.620.682.700.646.500.750 Cyclin-Dependent Kinase 2 58
D08.811.913.696.620.682.700.646.500.812 Cyclin-Dependent Kinase 3
D08.811.913.696.620.682.700.646.500.875 Cyclin-Dependent Kinase 4 79
D08.811.913.696.620.682.700.646.500.937 Cyclin-Dependent Kinase 6 66
D08.811.913.696.620.682.700.646.500.968 Cyclin-Dependent Kinase 8 1
D08.811.913.696.620.682.700.646.500.984 Maturation-Promoting Factor 14
D08.811.913.696.620.682.700.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 581
D12.776.167 Cell Cycle Proteins 330
D12.776.167.200 Cyclin-Dependent Kinases 231
D12.776.167.200.067 CDC2-CDC28 Kinases 25
D12.776.167.200.323 Cyclin-Dependent Kinase 2 58
D12.776.167.200.387 Cyclin-Dependent Kinase 3
D12.776.167.200.451 Cyclin-Dependent Kinase 4 79
D12.776.167.200.515 Cyclin-Dependent Kinase 6 66
D12.776.167.200.548 Cyclin-Dependent Kinase 8 1
D12.776.167.200.580 Maturation-Promoting Factor 14
D12.776.167.200.790 Cyclin-Dependent Kinase-Activating Kinase 2
D12.776.476 Intracellular Signaling Peptides and Proteins 175
D12.776.476.563 Protein Serine-Threonine Kinases 273
D12.776.476.563.646 Proline-Directed Protein Kinases 1
D12.776.476.563.646.500 Cyclin-Dependent Kinases 231
D12.776.476.563.646.500.500 CDC2-CDC28 Kinases 25
D12.776.476.563.646.500.750 Cyclin-Dependent Kinase 2 58
D12.776.476.563.646.500.812 Cyclin-Dependent Kinase 3
D12.776.476.563.646.500.875 Cyclin-Dependent Kinase 4 79
D12.776.476.563.646.500.937 Cyclin-Dependent Kinase 6 66
D12.776.476.563.646.500.968 Cyclin-Dependent Kinase 8 1
D12.776.476.563.646.500.984 Maturation-Promoting Factor 14
D12.776.476.563.646.500.992 Cyclin-Dependent Kinase-Activating Kinase 2

CDK4 protein, human Chemical MeSH Browser

Cdk4 protein, Drosophila Chemical MeSH Browser

Cdk4 protein, Xenopus Chemical MeSH Browser

Cdk4 protein, mouse Chemical MeSH Browser

Cdk4 protein, rat Chemical MeSH Browser

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