Janus Kinase 2 [Janus kinasa 2]
- Terms
-
Janus kináza 2
Janusova kinasa 2
Janusova kináza 2
protein-tyrosinkinasa JAK-2
protein-tyrosinkinasa JAK2
tyrosinkináza JAK2
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JAK-2 Protein Tyrosine Kinase
JAK2 Protein Tyrosine Kinase
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
- DUI
- D053614 MeSH Browser
- CUI
- M0203030
- History note
- 2007(1992)
- Public note
- 2007; JANUS KINASE 2 was indexed under PROTEIN-TYROSINE KINASE & PROTO-ONCOGENE PROTEINS 1992-2006
Allowable subheadings
- AD
- administration & dosage 3
- AE
- adverse effects 5
- AN
- analysis
- AI
- antagonists & inhibitors 16
- BI
- biosynthesis
- BL
- blood
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects 3
- EC
- economics
- GE
- genetics 56
- HI
- history
- IM
- immunology 4
- IP
- isolation & purification 3
- ME
- metabolism 10
- PK
- pharmacokinetics 5
- PD
- pharmacology 1
- PH
- physiology 2
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use 9
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
JAK2 protein, human Chemical MeSH Browser
Jak2 protein, mouse Chemical MeSH Browser
Jak2 protein, rat Chemical MeSH Browser
TEL-JAK2 fusion protein, human Chemical MeSH Browser
TEL-JAK2 fusion protein, mouse Chemical MeSH Browser