Hypoxia training can improve endurance performance. However, the specific benefits mechanism of hypoxia training is controversial, and there are just a few studies on the peripheral adaptation to hypoxia training. The main objective of this study was to observe the effects of hypoxia training on cutaneous blood flow (CBF), hypoxia-inducible factor (HIF), nitric oxide (NO), and vascular endothelial growth factor (VEGF). Twenty rowers were divided into two groups for four weeks of training, either hypoxia training (Living High, Exercise High and Training Low, HHL) or normoxia training (NOM). We tested cutaneous microcirculation by laser Doppler flowmeter and blood serum parameters by ELISA. HHL group improved the VO(2peak) and power at blood lactic acid of 4 mmol/l (P(4)) significantly. The CBF and the concentration of moving blood cells (CMBC) in the forearm of individuals in the HHL group increased significantly at the first week. The HIF level of the individuals in the HHL group increased at the fourth week. The NO of HHL group increased significantly at the fourth week. In collusion, four weeks of HHL training resulted in increased forearm cutaneous blood flow and transcutaneous oxygen pressure. HHL increases rowers' NO and VEGF, which may be the mechanism of increased blood flow. The increased of CBF seems to be related with improving performance.

• MeSH
• biologické markery krev   MeSH
• časové faktory MeSH
• faktor 1 indukovatelný hypoxií krev   MeSH
• fyzická vytrvalost * MeSH
• fyziologická neovaskularizace MeSH
• hypoxie patofyziologie   MeSH
• kondiční příprava metody   MeSH
• kůže krevní zásobení   MeSH
• lidé MeSH
• mikrocirkulace * MeSH
• mladiství MeSH
• mladý dospělý MeSH
• oxid dusnatý krev   MeSH
• regionální krevní průtok MeSH
• rychlost toku krve MeSH
• spotřeba kyslíku MeSH
• svalová síla MeSH
• vaskulární endoteliální růstové faktory krev   MeSH
• vazodilatace MeSH
• vodní sporty * MeSH
• Check Tag
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH