Despite development in cancer treatment and prevention options during the past few years, cancer of the pancreas remains a diagnosis associated with poor prognosis and limited options for prevention. Diet has proven to be an important risk factor for development of many types of cancer, particularly for cancers of the digestive system. Still, evidence regarding its relation to pancreatic cancer remains ambiguous. To investigate the relationship between diet and pancreatic cancer, an analysis of dietary patterns in participants from the Norwegian Women and Cancer Study (n = 89,156; 305 pancreatic cancer cases) was performed. Cox regression analysis was used for studying possible associations between dietary patterns, derived from principal component analysis, and pancreatic cancer incidence. The four most prominent dietary patterns were identified and described: European pattern, animal food consumers' dietary pattern, traditional Norwegian pattern, and alcohol-abstaining dietary pattern. In analysis without adjustment for confounders, being in the highest tertile of the abstaining dietary pattern was associated with lower risk of pancreatic cancer in comparison to the lowest tertile (hazard ratios [HR]: 0.66, 95% confidence interval [CI]: 0.49-0.89). After additional adjustment for height and smoking status, no dietary pattern was associated with increased pancreatic cancer risk, nor was there any difference in effect estimates between strata of smokers and non-smokers. The results of our current analysis do not support the role of major dietary patterns in the development of pancreatic cancer.
- Publikační typ
- časopisecké články MeSH
To summarize and evaluate the evidence on the health impact of a vegan diet, we conducted an umbrella review of systematic reviews and meta-analyses. PubMed, Cochrane Library, Web of Science and Epistemonikos were searched up to September 2021. Meta-analyses were recalculated by using a random effects model. The certainty of evidence (CoE) was evaluated by the GRADE approach. For the general healthy population, a vegan diet was effective for reducing body weight [MD (95% CI): -2.52 kg (-3.06, -1.98), n = 8 RCTs; moderate CoE] and was associated with further health benefits (with low CoE), including a lower risk of cancer incidence [SRR (95% CI): 0.84 (0.75, 0.95), n = 2] and a trend for lower risk of all-cause mortality [SRR (95% CI): 0.87 (0.75, 1.01), n = 2], as well as lower ApoB levels [MD (95% CI): -0.19 μmol/L (-0.23, -0.15), n = 7 RCTs). The findings suggested adverse associations for a vegan diet with risk of fractures [SRR (95% CI): 1.46 (1.03, 2.07), n = 3; low CoE]. For persons with diabetes or at high CVD risk, a vegan diet reduced measures of adiposity, total cholesterol, LDL and improved glycemic control (CoE moderate to low). A vegan diet may have the potential for the prevention of cardiometabolic health, but it may also impair bone health. More well-conducted primary studies are warranted.
- MeSH
- dieta veganská * MeSH
- hodnocení rizik MeSH
- lidé MeSH
- nádory * prevence a kontrola MeSH
- systematický přehled jako téma MeSH
- tělesná hmotnost MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
OBJECTIVE: During last years, a significant increase of HIV infection transmitted through sexual intercourse among young adults has been reported in the Czech Republic. The issue of prevention, where sexual education belongs to an important preventive tool, is much more topical than ever before. The level of knowledge and attitudes related to HIV/AIDS among adolescents has not been assessed so far. The aim of our study was to explore this field in a nationally representative sample. METHODS: Information was obtained using an anonymous questionnaire that was filled in by 1,627 adolescents 13 to 15 years old selected from a representative sample of 25 elementary and grammar schools in the Czech Republic. RESULTS: Based on the survey results, good knowledge regarding primary HIV/AIDS prevention was noted in the majority of respondents who however tended to stigmatize HIV positive people. CONCLUSION: The study has confirmed the importance of school as the main source of information (reported by 50.8% of respondents). The result of our study can serve as a starting point in assessment and comparison of the effect of various educational programmes.
- MeSH
- HIV infekce prevence a kontrola přenos MeSH
- lidé MeSH
- mladiství MeSH
- průzkumy a dotazníky MeSH
- sexuálně přenosné nemoci virové prevence a kontrola přenos MeSH
- zdraví - znalosti, postoje, praxe * MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
OBJECTIVES: The study examined appearance and body satisfaction in adolescents. For these purposes, data from the European Longitudinal Study of Pregnancy and Childhood in the Czech Republic were used. METHODS: The data were collected in 2010 and the sample comprised 3,105 18-year-old respondents. RESULTS: The research found that the respondents who wished to reduce their weight were mostly women with BMI in the normal range. Based on the body cathexis scale, we found that women compared to men are more critical of stomach, hips, buttocks, and thighs, as well as overall weight and figure. The results showed that criticism of their weight from their immediate environment is unpleasant to both female and male adolescents to such an extent that it makes them try to reduce it. However, it is clear that girls are altogether less satisfied with their bodies than boys. CONCLUSION: For both genders, body dissatisfaction is most likely enhanced by critical comments from peers and parents about appearance, body weight etc.
- MeSH
- lidé MeSH
- longitudinální studie MeSH
- mladiství MeSH
- osobní uspokojení * MeSH
- představa o vlastním těle psychologie MeSH
- psychologie adolescentů * MeSH
- zdravotnické přehledy MeSH
- Check Tag
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Česká republika MeSH
