The aim of our study was to evaluate differences between males and females based on patterns of costal cartilage ossification and also with respect to ageing. We provided diagnosis of ossifications from two files of radiograms. The first group consisted of 1044 chest and abdominal radiograms of patients (537 men and 507 women), ranging in age from 10 to 95 years obtained by using conventional X-ray technique. The second group was a set of 55 radiograms of chest plate fragments of cadavers (29 men and 26 women) aged from 15 to 98, obtained by using soft X-ray imaging in the skiagraphic-skiascopic unit. Ossifications were identified in more than 80% of the cases. They appear in puberta and their occurrence increases with age. The peripheral ossification pattern, typically the male pattern, is characterized by subperichondral deposits which contour the upper and lower margin of cartilage. The female, central lingual ossification pattern, is characterized by the pyramidal (lingual) shape of ossifications with a peak towards the sternum. The existence of another typical female central globular model of ossification was not confirmed in the file of cadavers. Central globular foci were found in both sexes (62% of women and 34% of men) from the 3rd decade. In the sample of Caucasian men and women (Czech population) we detected a frequent occurrence of costal cartilage ossification. Peripheral and central lingual patterns are highly predictive for sex determination. Globular loci of ossifications can be used for age estimation.
- MeSH
- běloši MeSH
- chrupavka radiografie MeSH
- dítě MeSH
- dospělí MeSH
- heterotopická osifikace MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- soudní antropologie MeSH
- stárnutí MeSH
- určení kostního věku metody MeSH
- určení pohlaví podle kostry metody MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Geografické názvy
- Česká republika MeSH
This study reports changes in costal cartilages that appear at the microscopic level throughout life, especially during the ossification process. The work builds on the results of our previous X-ray study, which confirmed the presence of two sexually dimorphic ossification patterns. This led to questions about the existence of additional sex-specific patterns that relate to the ossification process in costal cartilages. Samples of costal cartilages and adjacent parts of the bones were obtained from the autopsies of 17 corpses. The age range among the cadavers varied greatly, from a newborn baby to 91 years of age. Sections of costal cartilage were routinely processed and stained. Alkaline phosphatase activity was detected using histochemical methods. Collagens type II and X were detected immunohistochemically by monoclonal antibodies. The results of our study show that ossification of costal cartilages can take place in the form of two individual processes, localization and time-separate. Endochondral ossifications in the region of the costochondral zone appear in the first decade, and they correspond to ossifications detected by X-ray in the second decade. The location of sex-specific ossifications is determined by the penetration of cartilage canals into the metaphysial part of the rib. Endochondral intramembranous ossifications in the reserve zone appear after the third decade. These types of ossifications correspond to central globular ossifications detected by X-ray, and they are not sexually dimorphic. They can serve for accurate estimation of age.
- MeSH
- alkalická fosfatasa metabolismus MeSH
- chondrocyty metabolismus MeSH
- chrupavka metabolismus ultrastruktura MeSH
- dítě MeSH
- dospělí MeSH
- imunohistochemie MeSH
- kojenec MeSH
- kolagen typ II metabolismus MeSH
- kolagen typ X metabolismus MeSH
- lidé středního věku MeSH
- lidé MeSH
- mikroskopie MeSH
- mladiství MeSH
- mladý dospělý MeSH
- novorozenec MeSH
- osteoblasty metabolismus MeSH
- osteogeneze MeSH
- předškolní dítě MeSH
- proteoglykany metabolismus MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- soudní antropologie MeSH
- stárnutí MeSH
- zvětšování buněk MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- kojenec MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mladý dospělý MeSH
- mužské pohlaví MeSH
- novorozenec MeSH
- předškolní dítě MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- MeSH
- břicho MeSH
- chrupavka patologie radiografie MeSH
- dítě MeSH
- dospělí MeSH
- fyziologická kalcifikace MeSH
- hrudník MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- osteogeneze * MeSH
- rentgendiagnostika hrudníku MeSH
- retrospektivní studie MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- sexuální faktory * MeSH
- stárnutí MeSH
- určení kostního věku statistika a číselné údaje MeSH
- věkové faktory MeSH
- žebra * patologie radiografie MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
Mineralization and ossification in the human costal cartilages were studied radiologically. The aim of our study was to evaluate differences between males and females with respect to patterns of costal cartilage calcification and also with respect to ageing. Material for this study consists of 1044 chest and abdominal radiograms of the Czech population from the Department of Radiology (537 males and 507 females). Further radiograms of 18 chest plates were obtained at routine necropsy of cadavers. The radiograms were examined for pattern of ossification of the costal cartilage. The first rib cartilages were not considered because there are no sex differences. The lower ribs exhibit sexual dimorphism. Mineralization and ossification changes appear at the end of puberty and their occurrence increases with age. The sexual difference in pattern of human costal cartilages is statistically significant and thus highly predictive of sex determination.
- MeSH
- chrupavka anatomie a histologie MeSH
- dítě MeSH
- dospělí MeSH
- fyziologická kalcifikace MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- pohlavní dimorfismus MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- žebra MeSH
- Check Tag
- dítě MeSH
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mladiství MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
