BACKGROUND: Newly diagnosed people with multiple sclerosis frequently report fatigue, pain, depression and anxiety. Preventative programmes may be beneficial, but there is limited evidence of their effectiveness, especially long-term follow-up. METHODS: The programme consisted of 6-month face to face intervention (an introductory workshop, psychology-led group sessions and individual physical therapy) followed by 6-month self-guided therapy. Outcome measures were taken at baseline, 6 and 12 months. Primary outcomes measures were self-report questionnaires for fatigue, satisfaction with life and disease acceptance. Secondary outcomes were spirometry, spiroergometric parameters and neuroactive steroid levels. RESULTS: From 22 participants enrolled, 17 completed the first 6 months and 13 the follow-up. Fatigue measured on the Fatigue scale for motor and cognitive functions decreased significantly at 6 months (p = 0.035) and at follow-up (p = 0.007). The Modified Fatigue Impact Scale (p = 0.035) and Satisfaction With Life Scale (p = 0.007) significantly increased at follow-up. Spirometry, spiroergometric parameters, steroid hormones and neuroactive steroids levels did not change significantly. CONCLUSION: This programme reduces fatigue and improves satisfaction with life in this patient group with improvements sustained at 12 months. People who participated more frequently showed greater benefit. CLINICAL REHABILITATION IMPACT: The paper describes the effects of a complex preventative intervention for people with newly diagnosed Multiple Sclerosis. The study found that this programme reduces fatigue and improves satisfaction with life with long-term benefit (at 12-month follow up). The individuals who participated less frequently experienced fewer benefits.

• Publikační typ
• časopisecké články MeSH

• MeSH
• diagnostické techniky neurologické klasifikace   MeSH
• hyperkinetická porucha klasifikace   patologie   MeSH
• lidé MeSH
• percepční poruchy diagnóza   klasifikace   patologie   MeSH
• pozornost * fyziologie   klasifikace   MeSH
• teoretické modely MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• přehledy MeSH

• MeSH
• diagnostické techniky neurologické klasifikace   normy   MeSH
• hyperkinetická porucha diagnóza   klasifikace   MeSH
• lidé MeSH
• nemoci mozku komplikace   MeSH
• neuropsychologické testy normy   MeSH
• percepční poruchy diagnóza   etiologie   klasifikace   MeSH
• pozornost * fyziologie   MeSH
• teoretické modely MeSH
• Check Tag
• lidé MeSH

• MeSH
• afázie rehabilitace   terapie   MeSH
• dysartrie rehabilitace   terapie   MeSH
• kognitivně behaviorální terapie MeSH
• komunikační poruchy rehabilitace   terapie   MeSH
• řečová terapie MeSH
• skupinová psychoterapie MeSH

• Konspekt
• Fyzioterapie. Psychoterapie. Alternativní lékařství
• NLK Obory
• psychoterapie
• NLK Publikační typ
• pracovní listy