Laser speckle contrast imaging (LSCI) is a noninvasive method, which uses scattered light to estimate the flow of a fluid containing scatterers. Thus, it can be especially used to estimate blood flow. Laser light is randomly scattered on the tissue and this refracted light interfere with reflected light, giving birth to laser speckle noise. As the light scatters on moving red blood cells, the speckle pattern is blurred due to the exposition time. This blurring is a function of velocity which can be estimated from the degree of blur, termed as speckle contrast. Therefore, blood cells act like contrast agent, outlining blood vessels. The simple setup, unnecessary contrast agent and unharming nature are making LSCI a popular tool for studying blood flow dynamics and vascular structure. This paper presents a new, simple experimental setup and image processing methods to treat laser speckle images aiming to estimate relative blood flow and vascular structure.
- Klíčová slova
- registrace ultrazvukových sekvencí,
- MeSH
- kontrastní látky MeSH
- lidé MeSH
- perfuzní zobrazování MeSH
- počítačové zpracování obrazu * MeSH
- ultrasonografie * metody využití MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
- MeSH
- kontrastní látky * MeSH
- lidé MeSH
- matematika MeSH
- modely nemocí na zvířatech MeSH
- perfuzní zobrazování * MeSH
- prasata MeSH
- ultrasonografie * metody MeSH
- výzkum MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- práce podpořená grantem MeSH
It has been shown that besides positron emission tomography, single photon emission computed tomography and magnetic resonance imaging; contrast echocardiography can be used for qualitative and quantitative myocardial perfusion assessment. In this review, the properties of ultrasound contrast agents, imaging techniques and acquisition methods are shortly described and the possibilities of perfusion echocardiography are summarized. The main focus is put on the description of three perfusion models: mathematical models, physical models assuming an ideal inflow and physical models including inflow measurement.
- MeSH
- echokardiografie MeSH
- interpretace obrazu počítačem MeSH
- kontrastní látky diagnostické užití MeSH
- koronární cirkulace MeSH
- lidé MeSH
- modely kardiovaskulární MeSH
- prediktivní hodnota testů MeSH
- zobrazování myokardiální perfuze metody MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- přehledy MeSH
