Plants form associations with different microbes; some promote their growth and protect from biotic and abiotic stresses in different ways. However, the biological role of fungi associated with the rhizosphere of medicinal plants is not well explored. In the present study, Colletotrichum gloeosporioides, and Aspergillus fumigatus isolated from the rhizosphere of Dillenia indica were screened for their phosphate solubilization and indole-3-acetic acid (IAA) production potential. The selected fungal strains were identified by macroscopic, microscopic, and molecular characteristics. Phosphate solubilization was qualitatively and quantitatively evaluated using Pikovskaya's (PVK) agar and PVK broth medium using different substrates such as AlPO4, Ca3(PO4)2, and FePO4. Colletotrichum gloeosporioides and Aspergillus fumigatus with respect to the phosphate source showed solubilization index (SI) of 1.7 ± 0.03 and 2.1 ± 0.04, and solubilized phosphate up to 138.8 ± 0.058 μg/mL and 121.6 ± 0.062 μg/mL. These fungal strains are also good producers of IAA and significantly enhance the growth of Vigna radiata and Cicer arietinum seedlings. This is the first report on A. fumigatus and C. gloeosporioides from the rhizosphere of Dillenia indica and their phosphate solubilization and IAA production ability.
Cells produce reactive oxygen species (ROS) as a metabolic by-product. ROS molecules trigger oxidative stress as a feedback response that significantly initiates biological processes such as autophagy, apoptosis, and necrosis. Furthermore, extensive research has revealed that hydrogen peroxide (H2O2) is an important ROS entity and plays a crucial role in several physiological processes, including cell differentiation, cell signalling, and apoptosis. However, excessive production of H2O2 has been shown to disrupt biomolecules and cell organelles, leading to an inflammatory response and contributing to the development of health complications such as collagen deposition, aging, liver fibrosis, sepsis, ulcerative colitis, etc. Extracts of different plant species, phytochemicals, and Lactobacillus sp (probiotic) have been reported for their anti-oxidant potential. In this view, the researchers have gained significant interest in exploring the potential plants spp., their phytochemicals, and the potential of Lactobacillus sp. strains that exhibit anti-oxidant properties and health benefits. Thus, the current review focuses on comprehending the information related to the formation of H2O2, the factors influencing it, and their pathophysiology imposed on human health. Moreover, this review also discussed the anti-oxidant potential and role of different extract of plants, Lactobacillus sp. and their fermented products in curbing H2O2‐induced oxidative stress in both in-vitro and in-vivo models via boosting the anti-oxidative activity, inhibiting of important enzyme release and downregulation of cytochrome c, cleaved caspases-3, - 8, and - 9 expression. In particular, this knowledge will assist R&D sections in biopharmaceutical and food industries in developing herbal medicine and probiotics-based or derived food products that can effectively alleviate oxidative stress issues induced by H2O2 generation.
- MeSH
- antioxidancia * farmakologie metabolismus MeSH
- apoptóza MeSH
- lidé MeSH
- oxidační stres MeSH
- peroxid vodíku farmakologie MeSH
- probiotika * farmakologie MeSH
- reaktivní formy kyslíku metabolismus MeSH
- rostliny metabolismus MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- přehledy MeSH
