Macromolecular conjugates of a natural polysaccharide, hyaluronic acid, with diethylenetriaminepentaacetic acid (DTPA)-metal complexes were synthesized and characterized by FTIR, NMR, SEC-MALLS and ICP analysis. Several parameters of the cross-linking reaction as molecular weight of starting HA, temperature, equivalent of DTPA bis-anhydride, concentration of HA, presence of transacylation catalyst DMAP and reaction time were studied. The mechanism for the reaction was suggested and relationship between the molecular weight assigned by SEC-MALLS, reaction parameters and rheological properties of the final cross-linked products were investigated.
Na naše oddělení jsou přijímáni pacienti s defekty měkkých tkání, které se řeší různými druhy plastických operací. Rády bychom přiblížily péči o pacienty, kteří podstupují jednu z nejnáročnějších plastických operací -krytí defektu volným lalokem.
We admit patients with defects of soft tissues which are treated by various plastic surgeries. We would like to present the care of patients who undergo one of the most difficult plastic surgeries - covering of the defect with free flap.
- MeSH
- chirurgické laloky MeSH
- hojení ran MeSH
- lidé MeSH
- senioři MeSH
- zákroky plastické chirurgie MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH