Therapeutic applications of microbial secondary metabolites provided the opportunity for the discovery of antibiotics, immunosuppressants, cholesterol lowering and anticancer drugs. Most natural products used in medicine are isolated from plants. The isolation is usually quite a difficult, expensive and non-ecological process. Therefore we focused on microbial sources of enzyme inhibitors. Although many substances were already discovered in the last century, their potential and various modifications are still promising. An interest in enzyme inhibitors is steadily growing due to their potential in the management of metabolic disorders and serious diseases and also due to finding more effective and safer drugs.

• MeSH
• alfa-amylasy antagonisté a inhibitory   terapeutické užití   MeSH
• alfa-glukosidasy antagonisté a inhibitory   terapeutické užití   MeSH
• beta-glukosidasa antagonisté a inhibitory   terapeutické užití   MeSH
• biologické přípravky * metabolismus   terapeutické užití   MeSH
• hydrolasy * antagonisté a inhibitory   terapeutické užití   MeSH
• inhibitory adenosindeaminasy aplikace a dávkování   terapeutické užití   MeSH
• inhibitory enzymů * terapeutické užití   MeSH
• lidé MeSH
• mikrobiologické jevy * MeSH
• neuraminidasa antagonisté a inhibitory   terapeutické užití   MeSH
• proteasy MeSH
• Check Tag
• lidé MeSH

• MeSH
• beta-glukosidasa terapeutické užití   MeSH
• Gaucherova nemoc * diagnóza   genetika   terapie   MeSH
• lidé MeSH
• Check Tag
• lidé MeSH
• mužské pohlaví MeSH
• Publikační typ
• kazuistiky MeSH
• práce podpořená grantem MeSH