The association between kidney and liver polycystosis and arterial aneurysms is well documented. However, it remains unclear whether these patients are at increased risk of malignant transformation. In this article, we describe a case of a primary angiosarcoma of the femoral artery with metastatic spread into the lungs and hilar lymph node arising in a 74-year-old man with kidney and liver polycystosis and multiple arterial aneurysms.
- MeSH
- aneurysma komplikace diagnóza MeSH
- arteria femoralis * chemie patologie MeSH
- biopsie MeSH
- cysty komplikace diagnóza MeSH
- hemangiosarkom chemie komplikace sekundární MeSH
- imunohistochemie MeSH
- lidé MeSH
- lymfatické metastázy MeSH
- nádorové biomarkery analýza MeSH
- nádory plic chemie komplikace sekundární MeSH
- nemoci jater komplikace diagnóza MeSH
- polycystická choroba ledvin komplikace diagnóza MeSH
- senioři MeSH
- vaskulární nádory chemie komplikace patologie MeSH
- Check Tag
- lidé MeSH
- senioři MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- systematický přehled MeSH
The authors report a case of cutaneous angiosarcoma, composed predominantly of cytologically bland foamy cells, mimicking cutaneous xanthoma, dermal clear cell mesenchymal neoplasm, or clear cell dermatofibroma. The tumor occurred on the forehead and scalp of an 86-year-old white man with no history of radiation exposure. The tumor cells were positive for CD31, CD34, D2-40, FLI-1, and ERG, and were negative for CD68 and CD163. Conventional vasoformative areas, with atypia and mitoses that led to the correct final diagnosis, were found only in 1 of the 2 performed biopsies. Foamy cell angiosarcoma is probably one of the least common variants of cutaneous angiosarcoma and represents an important diagnostic pitfall.
- MeSH
- biopsie MeSH
- diferenciální diagnóza MeSH
- hemangiosarkom chemie patologie MeSH
- imunohistochemie MeSH
- kožní nemoci metabolismus patologie MeSH
- lidé MeSH
- nádorové biomarkery analýza MeSH
- nádory hlavy a krku chemie patologie MeSH
- nádory kůže chemie patologie MeSH
- prediktivní hodnota testů MeSH
- senioři nad 80 let MeSH
- skalp chemie patologie MeSH
- xantomatóza metabolismus patologie MeSH
- Check Tag
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH