Phytophthora cinnamomi is one of the most invasive tree pathogens that devastates wild and cultivated forests. Due to its wide host range, knowledge of the infection process at the molecular level is lacking for most of its tree hosts. To expand the repertoire of studied Phytophthora-woody plant interactions and identify molecular mechanisms that can facilitate discovery of novel ways to control its spread and damaging effects, we focused on the interaction between P. cinnamomi and sweet chestnut (Castanea sativa), an economically important tree for the wood processing industry. By using a combination of proteomics, metabolomics, and targeted hormonal analysis, we mapped the effects of P. cinnamomi attack on stem tissues immediately bordering the infection site and away from it. P. cinnamomi led to a massive reprogramming of the chestnut proteome and accumulation of the stress-related hormones salicylic acid (SA) and jasmonic acid (JA), indicating that stem inoculation can be used as an easily accessible model system to identify novel molecular players in P. cinnamomi pathogenicity.

• MeSH
• Cyclopentanes metabolism   MeSH
• Wood MeSH
• Fagaceae metabolism   microbiology   MeSH
• Homeostasis MeSH
• Plant Roots MeSH
• Salicylic Acid metabolism   MeSH
• Metabolomics MeSH
• Plant Diseases microbiology   MeSH
• Oxylipins metabolism   MeSH
• Phytophthora pathogenicity   MeSH
• Proteomics MeSH
• Plant Growth Regulators metabolism   MeSH
• Signal Transduction MeSH
• Binding Sites MeSH
• Computational Biology MeSH
• Publication type
• Journal Article MeSH