Two multidrug resistance (MDR) plasmids, carrying the VIM-1-encoding integron In110, were characterized. Plasmid pLec-476cz (311,758 bp), from aLeclercia adecarboxylataisolate, consisted of an IncHI1 backbone, a MDR region, and two accessory elements. Plasmid pKpn-431cz (142,876 bp), from a sequence type 323 (ST323)Klebsiella pneumoniaeisolate, comprised IncFIIY-derived and pKPN3-like sequences and a mosaic region. A 40,400-bp sequence of pKpn-431cz was identical to the MDR region of pLec-476cz, indicating theen blocacquisition of the VIM-1-encoding region from one plasmid by the other.

• MeSH
• Bacterial Proteins genetics   MeSH
• beta-Lactamases genetics   MeSH
• beta-Lactam Resistance genetics   MeSH
• DNA, Bacterial genetics   MeSH
• Integrons genetics   MeSH
• Klebsiella pneumoniae drug effects   genetics   MeSH
• Humans MeSH
• Drug Resistance, Multiple, Bacterial genetics   MeSH
• Plasmids genetics   MeSH
• Base Sequence MeSH
• Sequence Analysis, DNA MeSH
• Check Tag
• Humans MeSH
• Publication type
• Journal Article MeSH
• Geographicals
• Czech Republic MeSH