Hypromellose, a semi-synthetic derivative of cellulose, is by far the most commonly used hydrophilic polymer for the development of oral controlled release dosage forms. Modulation of drug release can be achieved by combination of different viscosity grades of hypromellose or combination with other polymers including water insoluble, non-ionic or ionic polymers. These combinations of excipients are widely used in the formulation of standard and also modern dosage forms including matrix tablets, multilayer tablets, minitablets, floating gastroretentive system, mucoadhesive dosage forms, micro- and nanoparticles, 3D printed dosage forms, and nanofiber-based drug delivery systems.

• MeSH
• deriváty hypromelózy * chemie   farmakokinetika   MeSH
• farmaceutická chemie MeSH
• farmaceutické pomocné látky chemie   farmakokinetika   MeSH
• léky s prodlouženým účinkem chemická syntéza   chemie   farmakokinetika   MeSH
• tablety chemie   farmakokinetika   MeSH
• uvolňování léčiv MeSH
• Publikační typ
• práce podpořená grantem MeSH