- MeSH
- aspirace do dýchacích cest * etiologie komplikace terapie MeSH
- endoskopie metody MeSH
- gastroenteritida MeSH
- kojenec * MeSH
- lidé MeSH
- ořechy škodlivé účinky MeSH
- rentgendiagnostika hrudníku metody MeSH
- výsledek terapie MeSH
- zvracení etiologie MeSH
- Check Tag
- kojenec * MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- kazuistiky MeSH
Elevated levels of nausea and vomiting in pregnancy (NVP) and disgust sensitivity have been observed in the first trimester and both are thought to have a protective function for the mother and her fetus. Their aetiology is not clear, however, with previous studies attributing elevated NVP and disgust to various factors including endocrine changes, immunological changes, and psychological variables. To date, no study has directly assessed the relationship between disgust and NVP. Here, we prospectively collected two independent samples (S1 and S2; n1 = 201, n2 = 391) of women in the first trimester of pregnancy, who completed the Index of Nausea, Vomiting, and Retching and the Disgust Scale-Revised. We also measured free β-human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A) in maternal serum. Our results did not confirm any association between NVP and disgust; in addition, they indicate that NVP and disgust may have different proximate causes. Disgust sensitivity was significantly negatively correlated with free β-hCG and (only in S1) with PAPP-A. In contrast, NVP was significantly positively associated with free β-hCG levels and (only in S1) with PAPP-A. While low hCG levels seem to be an important indicator for activation of the behavioral immune system in the first trimester, increased hCG levels play a role in stronger symptoms of NVP, a result consistent with previous studies. Levels of PAPP-A are likely part of a larger network of immunological and endocrine responses and do not appear to provide sufficient information for predicting women's NVP and disgust sensitivity.
- MeSH
- biologické markery MeSH
- komplikace těhotenství * MeSH
- lidé MeSH
- lidský choriogonadotropin, beta podjednotka MeSH
- nauzea etiologie MeSH
- odpor * MeSH
- první trimestr těhotenství MeSH
- těhotenský plazmatický protein A metabolismus MeSH
- těhotenství MeSH
- zvracení etiologie MeSH
- Check Tag
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: A recent study focusing on dietary predictors of nausea and vomiting in pregnancy (NVP) found that women with higher levels of partner support, and those who had used oral contraception (OC) when they met the father, both tended to report less severe NVP compared with previous non-users or those with less supportive partners. We provide a further test of these factors, using a large sample of women from four countries who retrospectively scored their NVP experience during their first pregnancy. METHODS: We recruited women who had at least one child to participate in a retrospective online survey. In total 2321 women completed our questionnaire including items on demographics, hormonal contraception, NVP, and partner support. We used general linear models and path analysis to analyse our data. RESULTS: Women who had used OC when they met the father of their first child tended to report lower levels of NVP, but the effect size was small and did not survive adding the participant's country to the model. There was no relationship between NVP and partner support in couples who were still together, but there was a significant effect among those couples that had since separated: women whose ex-partner had been relatively supportive reported less severe NVP. Additional analyses showed that women who were older during their first pregnancy reported less severe NVP, and there were also robust differences between countries. CONCLUSIONS: These results provide further evidence for multiple influences on women's experience of NVP symptoms, including levels of perceived partner support.
- MeSH
- antikoncepce metody psychologie MeSH
- antikoncepční chování psychologie MeSH
- charakteristiky rodiny MeSH
- dítě MeSH
- internet MeSH
- komplikace těhotenství * etiologie prevence a kontrola psychologie MeSH
- kontraceptiva orální * aplikace a dávkování terapeutické užití MeSH
- lidé MeSH
- nauzea * etiologie prevence a kontrola psychologie MeSH
- retrospektivní studie MeSH
- sexuální partneři * psychologie MeSH
- sociální opora * psychologie MeSH
- těhotenství MeSH
- zdravotnické přehledy MeSH
- zvracení * etiologie prevence a kontrola psychologie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- těhotenství MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- multicentrická studie MeSH
- srovnávací studie MeSH
- MeSH
- antagonisté dopaminu terapeutické užití MeSH
- antagonisté muskarinových receptorů terapeutické užití MeSH
- antiemetika terapeutické užití MeSH
- antihistaminika terapeutické užití MeSH
- glukokortikoidy terapeutické užití MeSH
- kanabinoidy terapeutické užití MeSH
- lidé MeSH
- nádory komplikace MeSH
- nauzea etiologie farmakoterapie patofyziologie MeSH
- olanzapin aplikace a dávkování farmakologie MeSH
- zvracení * etiologie farmakoterapie patofyziologie MeSH
- Check Tag
- lidé MeSH
- MeSH
- bolesti hlavy etiologie patofyziologie MeSH
- intrakraniální hypertenze * diagnóza etiologie patofyziologie MeSH
- intrakraniální hypotenze * diagnóza etiologie patofyziologie MeSH
- intrakraniální tlak fyziologie MeSH
- lidé MeSH
- závrať etiologie MeSH
- zvracení etiologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- analgetika farmakologie terapeutické užití MeSH
- antagonisté dopaminu aplikace a dávkování farmakologie terapeutické užití MeSH
- antiemetika aplikace a dávkování farmakologie terapeutické užití MeSH
- antitumorózní látky škodlivé účinky MeSH
- lidé MeSH
- nádory * komplikace MeSH
- nauzea * etiologie farmakoterapie MeSH
- paliativní péče metody MeSH
- zvracení * etiologie farmakoterapie prevence a kontrola MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- dítě MeSH
- homeopatie * MeSH
- ketóza patologie terapie MeSH
- lidé MeSH
- materia medica aplikace a dávkování klasifikace terapeutické užití MeSH
- zvracení * etiologie terapie MeSH
- Check Tag
- dítě MeSH
- lidé MeSH
- Publikační typ
- přehledy MeSH
- MeSH
- antiemetika farmakologie terapeutické užití MeSH
- lidé MeSH
- nauzea * etiologie terapie MeSH
- zvracení * etiologie terapie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- přehledy MeSH