It has been estimated that up to 10% of hypercoagulable state manifestations in patients with inflammatory bowel disease (IBD) are ischemic strokes. The literature search through MEDLINE and EMBASE highlighted 33 case reports of IBD patients complicated with cerebral arterial infarction during the course of their disease. Most of these patients presented with either left or right sided hemiparesis on admission, while the most common site of arterial infarction was either the right or the left middle cerebral artery. Thrombocytosis and anemia were the most commonly observed potential risk factors for stroke in the laboratory analysis. Other coagulation abnormalities, hereditary thrombotic mutations, hyperhomocysteinemia, hyperlipidemia, structural cardiac abnormalities, endocarditis and cerebral artery vasculitis have also been reported in some of the cases that were reviewed. Even though many of these findings are commonly observed in IBD patients, literature data is still controversial about their causal relationship to ischemic stroke. Similarly, there is also lack of steady evidence and official guidelines for stroke management in both children and adults with IBD comorbidity. Finally, an algorithm based on both the American Heart Association and European Stroke Organization guidelines for stroke management and prevention in the general population, is presented as a reference point for the treatment of IBD patients who are complicated by an ischemic cerebral event.
- Klíčová slova
- Cerebral artery occlusion, Cerebral thromboembolism, Crohn's disease, Inflammatory bowel disease, Ischemic stroke, Ulcerative colitis,
- MeSH
- anemie komplikace MeSH
- cerebrální infarkt komplikace MeSH
- idiopatické střevní záněty komplikace MeSH
- lidé MeSH
- rizikové faktory MeSH
- trombocytóza komplikace MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
The term transient ischaemic attack (TIA) does not correspond to findings of new examination methods and is rather a matter of convention. The authors examined 19 patients with the diagnosis of TIA by CT and found in five a cerebral infarction. The dependence of cerebral infarction in TIA on age, sex, risk factors (hypertension, diabetes) and the duration of clinical symptomatology was not significant.
The author describes two clinical observations of migraine of the basilar artery: with infarction of the cerebellar hemisphere in a 21-year-old woman and migraine equivalents of transient homonymous hemianopsia in a 27-year-old man. The author analyzed the clinical picture and assessed seven diagnostic criteria of migraine of the basilar artery. In the prophylaxis of migrainous attacks in both instanes metipranolol-80 mg/day-proved effective.
- MeSH
- arteria basilaris * MeSH
- cerebrální infarkt komplikace MeSH
- dospělí MeSH
- lidé MeSH
- migréna etiologie MeSH
- nemoci mozečku komplikace MeSH
- vertebrobazilární insuficience komplikace MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
The polygram of night sleep was studied in 3 patients, who due to a lesion to the CNS and peripheral nervous system were in a state of long-term akinesia and artificial lung ventilation. The cyclic organization of sleep and its transition from stage to stage, as a whole corresponded with those in healthy subjects. However, there was a general tendency in all patients to a reduction of sleep spindles. There was also a tendency to the stability of heart rate during night sleep. The relationship between delta-sleep and sleep spindles and motor activity is discussed.
- MeSH
- amyotrofická laterální skleróza patofyziologie MeSH
- cerebrální infarkt komplikace MeSH
- dospělí MeSH
- elektroencefalografie MeSH
- lidé středního věku MeSH
- lidé MeSH
- myasthenia gravis patofyziologie MeSH
- paralýza patofyziologie MeSH
- pohybové poruchy patofyziologie MeSH
- spánek fyziologie MeSH
- srdeční frekvence * MeSH
- stadia spánku fyziologie MeSH
- umělé dýchání MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- MeSH
- alfa rytmus EEG * MeSH
- cerebrální infarkt komplikace diagnóza MeSH
- kóma diagnóza etiologie MeSH
- kvadruplegie etiologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- pons * MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH
- kazuistiky MeSH
- MeSH
- cerebrální infarkt komplikace MeSH
- dospělí MeSH
- hemiplegie etiologie patofyziologie MeSH
- hypertenze patofyziologie MeSH
- končetiny krevní zásobení MeSH
- kůže krevní zásobení MeSH
- lidé středního věku MeSH
- lidé MeSH
- mikrocirkulace patofyziologie MeSH
- regionální krevní průtok MeSH
- senioři MeSH
- svaly krevní zásobení MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- anglický abstrakt MeSH
- časopisecké články MeSH