Most cited article - PubMed ID 30223519
Nanoparticles as a Solution for Eliminating the Risk of Mycotoxins
A facet of nanorenaissance in plant pathology hailed the research on the development and application of nanoformulations or nanoproducts for the effective management of phytopathogens deterring the growth and yield of plants and thus the overall crop productivity. Zinc nanomaterials represent a versatile class of nanoproducts and nanoenabled devices as these nanomaterials can be synthesized in quantum amounts through economically affordable processes/approaches. Further, these nanomaterials exhibit potential targeted antimicrobial properties and low to negligible phytotoxicity activities that well-qualify them to be applied directly or in a deviant manner to accomplish significant antibacterial, antimycotic, antiviral, and antitoxigenic activities against diverse phytopathogens causing plant diseases. The photo-catalytic, fluorescent, and electron generating aspects associated with zinc nanomaterials have been utilized for the development of sensor systems (optical and electrochemical biosensors), enabling quick, early, sensitive, and on-field assessment or quantification of the test phytopathogen. However, the proficient use of Zn-derived nanomaterials in the management of plant pathogenic diseases as nanopesticides and on-field sensor system demands that the associated eco- and biosafety concerns should be well discerned and effectively sorted beforehand. Current and possible utilization of zinc-based nanostructures in plant disease diagnosis and management and their safety in the agroecosystem is highlighted.
- Keywords
- ecotoxicity, nanomaterial, nanosensors, phytopathogens, zinc,
- Publication type
- Journal Article MeSH
- Review MeSH
Mycotoxin management in agriculture is an essential challenge for maintaining the health of both animals and humans. Choosing the right adsorbent is still a question for many breeders and an important criterion for feed manufacturers. New adsorbents are still being sought. Graphene oxide is a promising material in the field of nanotechnology, which excels in its adsorption properties. Presented in vitro study investigates graphene oxide for the binding of mycotoxins from crushed wheat. The results show that graphene oxide has an adsorption capacity for aflatoxin 0.045 mg/g, zearalenone 0.53 mg/g and deoxynivalenol 1.69 mg/g at 37° C. In vitro simulation of crushed wheat digestion showed rapid adsorption during the gastric phase. Of the minerals, Mg, Cu and Zn were the most adsorbed. The applied dose of graphene oxide of 10 mg/g caused only a slight inhibition of the digestive enzymes α-amylase and trypsin compared to pepsin and gastric lipase. In vitro results indicated the suitability of graphene oxide in the adsorption of the aflatoxin, zearalenone and deoxynivalenol.
- MeSH
- Adsorption MeSH
- Aflatoxin B1 isolation & purification toxicity MeSH
- Gastrointestinal Absorption MeSH
- Graphite chemistry MeSH
- Food Contamination analysis prevention & control MeSH
- Animal Feed analysis toxicity MeSH
- Humans MeSH
- Mycotoxins isolation & purification toxicity MeSH
- Nanostructures chemistry MeSH
- Triticum chemistry toxicity MeSH
- In Vitro Techniques MeSH
- Digestion MeSH
- Trichothecenes isolation & purification toxicity MeSH
- Zearalenone isolation & purification toxicity MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Aflatoxin B1 MeSH
- deoxynivalenol MeSH Browser
- Graphite MeSH
- graphene oxide MeSH Browser
- Mycotoxins MeSH
- Trichothecenes MeSH
- Zearalenone MeSH