PROTEUS Dotaz Zobrazit nápovědu
- Klíčová slova
- PROTEUS INFECTIONS/epidemiology *,
- MeSH
- infekce bakteriemi rodu Proteus epidemiologie MeSH
- lidé MeSH
- Proteus vulgaris * MeSH
- Proteus * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Klíčová slova
- PROTEUS INFECTIONS *,
- MeSH
- infekce bakteriemi rodu Proteus * MeSH
- lidé MeSH
- Proteus vulgaris * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
BACKGROUND: In the rather rare urinary pathogen Proteus mirabilis resistance to antibiotics and ability to form biofilm were studied. MATERIAL AND METHODS: The strains Proteus mirabilis were isolated from urine samples from ambulatory and hospitalized patients diagnosed with urinary tract infection (UTI) between April 2008 and April 2010. Resistance to antibiotics was investigated using a disk diffusion antimicrobial susceptibility test. Biofilm formation was demonstrated by modified Christensen method. RESULTS: Two hundred and thirteen of P. mirabilis strains were tested. Eighty-two (38.5 %) strains were resistant to ampicillin, 49 (23.0 %) to cefalotin, 83 (39.0 %) to sulfamethoxazole/trimetoprim, 75 (35.2 %) to ciprofloxacin, 95 (44.6 %) to oxolinic acid, 54 (25.4 %) to gentamicin, and 72 (33.8 %) to chloramphenicol. There was significantly lower resistance to cefotaxime - 8 strains (3.8 %), ceftazidime - 8 (3.8 %), amoxicillin/clavulanic acid 17 (8.0 %) and aztreonam - 8 (3.8 %). No resistance to imipenem as well as to meropenem was found. Eight P. mirabilis strains were found to produce extended-spectrum beta-lactamase (ESBL). From the total of 213 strains tested, 28 (13.1 %) were able to form a biofilm. CONCLUSIONS: P. mirabilis was found to be more frequent in urine of men and older patients. Biofilm formation in urinary P. mirabilis strains was relatively low. The strains showed higher resistance to beta-lactams and quinolones; in the other cases, resistance was low.
- MeSH
- bakteriální léková rezistence * MeSH
- biofilmy * MeSH
- infekce bakteriemi rodu Proteus farmakoterapie mikrobiologie MeSH
- infekce močového ústrojí farmakoterapie mikrobiologie MeSH
- lidé MeSH
- mikrobiální testy citlivosti MeSH
- moč mikrobiologie MeSH
- Proteus mirabilis účinky léků izolace a purifikace fyziologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Klíčová slova
- PROTEUS *,
- MeSH
- biologické jevy * MeSH
- fyziologické jevy * MeSH
- lidé MeSH
- Proteus * MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
Lecithinase production is described as a new biochemical property of P. vulgaris strains grown in a selective agar medium containing brilliant green, crystal violet and lecithin (BCL agar), the authors' own modification of egg-yolk culture medium. By using this BCL agar as a medium inhibiting the swarming growth of P. vulgaris cultures the authors succeeded in identifying 12 lecithinase-positive strains among the P. vulgaris isolates obtained from patients with Crohn's disease. Of 50 P. mirabilis strains tested in parallel none gave the positive test for lecithinase production in this medium.
- MeSH
- Crohnova nemoc mikrobiologie MeSH
- fosfolipasy metabolismus MeSH
- infekce bakteriemi rodu Proteus mikrobiologie MeSH
- lidé MeSH
- Proteus vulgaris enzymologie MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- fosfolipasy MeSH
- MeSH
- dospělí MeSH
- infekce bakteriemi rodu Proteus farmakoterapie MeSH
- infekce močového ústrojí farmakoterapie MeSH
- kyselina nalidixová terapeutické užití MeSH
- lidé středního věku MeSH
- lidé MeSH
- senioři MeSH
- sulfamethoxazol terapeutické užití MeSH
- trimethoprim terapeutické užití MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- kyselina nalidixová MeSH
- sulfamethoxazol MeSH
- trimethoprim MeSH
- MeSH
- bakteriální vakcíny aplikace a dávkování MeSH
- Escherichia coli imunologie MeSH
- imunizace * MeSH
- infekce bakteriemi rodu Proteus prevence a kontrola MeSH
- infekce močového ústrojí prevence a kontrola MeSH
- infekce vyvolané Escherichia coli prevence a kontrola MeSH
- krysa rodu Rattus MeSH
- Proteus mirabilis imunologie MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- bakteriální vakcíny MeSH
- Klíčová slova
- BACTERIA *, PROTEUS *, TRYPTOPHAN *,
- MeSH
- Bacteria * MeSH
- deaminace MeSH
- oxidace-redukce * MeSH
- Proteus * MeSH
- tryptofan * MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- tryptofan * MeSH
In the years 1979, 1980, 1982-83, 1986-87 and 1992-93, 673 strains of P. mirabilis and 25 strains of P. vulgaris were isolated from the urinary tracts of patients at a Teaching Hospital in Brno. In 1982-83 and 1992-93, strains of P. mirabilis and P. vulgaris were isolated from the urine and faeces of two groups of Brno population and used as controls. Using the P/S typing method, 94.7% of hospital isolates and 85.5% of control strains could be differentiated by their types. The strains that could not be typed (8.2%) were classified as PO/SO or N types; in the remaining strains, 182 various P/S types could be distinguished. The strains that could not be typed occurred more frequently in control groups (48 out of 337) than in hospital isolates (37 out of 698). Over the whole period, P5/S6, S7, S9 and P1/S2, S11 were the prevailing P/S types of hospital isolates and were placed, together with related types, in groups P5 and P1, respectively. In 1982-83, a significant shift (p < 0.01) from the initially prevailing P5/S6, S7, S9 type to the P1/S2, S11 type of P. mirabilis was recorded. Approximately one third of the hospital isolates in all the periods examined was found to be sporadic, with the exception of 1992-93 when the sporadic strains doubled in frequency (p < 0.01). In control strains, the frequency of sporadic types was twice that of the hospital isolates (p < 0.01) in 1982-83 and, 1992-93, it was equal to the frequency of hospital isolates. This implied a fall in the presence of hospital-acquired strains in the last period of study.
- MeSH
- bakteriociny imunologie MeSH
- infekce bakteriemi rodu Proteus mikrobiologie MeSH
- infekce močového ústrojí mikrobiologie MeSH
- infekce spojené se zdravotní péčí mikrobiologie MeSH
- lidé MeSH
- longitudinální studie MeSH
- Proteus mirabilis klasifikace izolace a purifikace MeSH
- Proteus vulgaris klasifikace izolace a purifikace MeSH
- séroepidemiologické studie MeSH
- sérotypizace metody MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika epidemiologie MeSH
- Názvy látek
- bakteriociny MeSH
- proticine MeSH Prohlížeč
