AIM: To map the current seroprevalence of antibodies and vaccine coverage against viral hepatitis A (VHA) in the general population of the South Moravian Region (SMR). MATERIAL AND METHODS: During the VHA outbreak in 2016, nearly 3500 persons were investigated epidemiologically by the Regional Public Health Authority of the SMR within the anti-epidemic measures. The data collected were, among others, basic personal data and information whether the person has been vaccinated against VHA. For the reportedly vaccinated, the information was checked in the GP records or vaccination card. Those who reported to be unvaccinated were referred for serological testing. For the purposes of this retrospective prevalence study, available data on 3130 persons were analysed. The study population was divided into 10 age groups (0-4 years, 5-9 years, 10-14 years, 15-19 years, 20-24 years, 25-34 years, 35-44 years, 45-54 years, 55-65 years, and 65 years and over). The numbers of vaccinated persons with positive total antibodies and of those who tested negative were determined. The data obtained were statistically analysed using the Microsoft Excel tabular processor. RESULTS: Of the study cohort of 3130 persons, 659 (21.05 %) turned out to be seropositive, and 320 (10.22 %) of the seropositives were vaccinated. The seroprevalence rates in the age groups over 35 years were increasing with increasing age, being the highest (51.40 %) in those aged 65 years and older. The highest vaccine coverage rates were achieved in the age groups 10-14 years (20.73 %) and 15-19 years (20.77 %). CONCLUSION: The seroprevalence rates of antibodies against VHA in the general population of the SMR are very low (21.05 %), being even lower than previously reported. The vaccine coverage rate against VHA is 10.22 %. The results show higher vaccine coverage rates in those born after the vaccine against VHA was implemented. Children show the highest vaccine coverage rates. Adults tend to get vaccinated less often. This fact promotes the risk of infection spread and outbreaks, as recently evidenced by the spread of infection from persons engaging in risky behaviours to the general population of young working-age adults.

• Klíčová slova
• viral hepatitis A - seroprevalence - vaccine coverage rate - susceptibility.,
• MeSH
• dítě MeSH
• dospělí MeSH
• hepatitida A * epidemiologie   MeSH
• lidé MeSH
• retrospektivní studie MeSH
• senioři MeSH
• séroepidemiologické studie MeSH
• vakcinace statistika a číselné údaje   MeSH
• vakcíny * MeSH
• věkové faktory MeSH
• Check Tag
• dítě MeSH
• dospělí MeSH
• lidé MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika epidemiologie   MeSH
• Názvy látek
• vakcíny * MeSH

AIM: To ensure that children are vaccinated, different national governments use diverse strategies. We compared childhood vaccination coverage rates between New York State (NYS) and New Zealand (NZ) as the vaccination strategies are different. METHODS: We used vaccination records from the NYS Immunisation Information System and the National Immunisation Register of NZ to measure (i) vaccination coverage by school entry and by age six; (ii) coverage of different socio-demographic groups; and (iii) trend in vaccination coverage between 2011 and 2015. RESULTS: We analysed the records of 583 767 NYS children and 269 800 NZ children 7 years of age. NZ children were 3.3-21.5% more likely than NYS children to receive each of the vaccines. Compared to NYS, NZ children were 39.6% more likely to be up-to-date by the start of school and 28.1% more likely to be up-to-date by age 6 years. Both NYS and NZ had statistically significant increases in the proportion of children who were up to date on each vaccine and all vaccines by the start of school and by 6 years of age (P < 0.001). CONCLUSIONS: We identified under-vaccinated groups and examined the point in the vaccine series where children were most vulnerable to being under-vaccinated. This information is useful in targeting future investigations and interventions aimed at mitigating disparities in vaccine coverage. This comparison of regions with different vaccination programmes and policies is important when considering whether the particular vaccination coverage strategies of one region could be adapted and applied for the benefit of another.

• MeSH
• dítě MeSH
• incidence MeSH
• kontrola infekčních nemocí metody   MeSH
• lidé MeSH
• městské obyvatelstvo MeSH
• očkovací schéma MeSH
• pokrytí očkováním statistika a číselné údaje   MeSH
• poliovirové vakcíny aplikace a dávkování   MeSH
• předškolní dítě MeSH
• vakcína proti diftérii, tetanu a pertusi aplikace a dávkování   MeSH
• vakcína proti hepatitidě B aplikace a dávkování   MeSH
• vakcína proti spalničkám, příušnicím a zarděnkám aplikace a dávkování   MeSH
• venkovské obyvatelstvo MeSH
• virové vakcíny MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• mužské pohlaví MeSH
• předškolní dítě MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• srovnávací studie MeSH
• Geografické názvy
• New York MeSH
• Nový Zéland MeSH
• Názvy látek
• poliovirové vakcíny MeSH
• vakcína proti diftérii, tetanu a pertusi MeSH
• vakcína proti hepatitidě B MeSH
• vakcína proti spalničkám, příušnicím a zarděnkám MeSH
• virové vakcíny MeSH

INTRODUCTION: The Raise Awareness of Influenza Strategies in Europe (RAISE) group gathered information about the healthcare burden of influenza (hospitalizations, intensive care unit [ICU] admissions, and excess deaths), surveillance systems, and the vaccine coverage rate (VCR) in older adults in 18 European countries and Israel. AREAS COVERED: Published medical literature and official medical documentation on the influenza disease burden in the participating countries were reviewed from 2010/11 until the 2022/23 influenza seasons. Information on the framework for monitoring the disease burden and the provision for ensuring older adults had access to vaccination in their respective countries was provided. Data on influenza VCR in older adults were collected for the 2019/20 to 2022/23 influenza seasons. Data are reported descriptively. EXPERT OPINION: Influenza presents a significant healthcare burden in older adults. Reporting outcomes across participating countries is heterogeneous, highlighting the need for standardized approaches. Although older adults receive free influenza vaccination, vaccine uptake is highly variable among countries. Moreover, hospitalization rates remain high even in countries reporting a high VCR. Increased awareness and education on the burden of disease and the broader use of improved influenza vaccines for older adults may help reduce the disease burden on this population.

• Klíčová slova
• Influenza, Influenza surveillance, burden of disease, older adults, vaccine coverage rate,
• MeSH
• chřipka lidská * prevence a kontrola   epidemiologie   MeSH
• COVID-19 * prevence a kontrola   epidemiologie   MeSH
• hospitalizace * statistika a číselné údaje   MeSH
• lidé MeSH
• pokrytí očkováním * statistika a číselné údaje   MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• vakcíny proti chřipce * aplikace a dávkování   MeSH
• Check Tag
• lidé MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• Geografické názvy
• Evropa epidemiologie   MeSH
• Izrael epidemiologie   MeSH
• Názvy látek
• vakcíny proti chřipce * MeSH

Seasonal influenza can have serious morbid consequences and can even result in death, particularly in at-risk populations, including healthcare professionals (HCPs), elderly and those living with a medical risk condition. Although in Europe recommendations exist for annual influenza vaccination in these populations in most countries, the vaccination coverage rate (VCR) is often well below the World Health Organization target of 75% coverage. In our previous survey in 2009 we showed that some elements of national vaccination policies, e.g. reminder systems, strong official recommendation, and easy access, seemed to contribute to achieving higher influenza VCRs among elderly. We repeated the survey in 2016, using the same methodology to assess changes in influenza VCRs among the elderly and in the impact of policy elements on these VCRs. In addition, we collected information about VCRs among HCPs, and those living with a medical risk condition. The median VCR in the 21 countries that had recommendations for influenza vaccination in the elderly was 35.3%, ranging from 1.1% in Estonia to 74.5% in Scotland. The average VCRs for HCPs and those living with medical risk conditions, available in 17 and 10 countries, respectively, were 28.3% (range 7% in Czech Republic to 59.1% in Portugal) and 32.2% (range from 20.0% in the Czech Republic and Hungary to 59.6% in Portugal), respectively. Fewer countries were able to provide data from HCP and those living with medical risk conditions. Since the initial survey during the 2007-2008 influenza season, VCRs have decreased in the elderly in the majority of countries, thus, achieving high VCRs in the elderly and the other target groups is still a major public health challenge in Europe. This could be addressed by the identification, assessment and sharing of best practice for influenza vaccination policies.

• Klíčová slova
• Elderly, Seasonal influenza vaccination, Vaccination coverage, Vaccination policies, healthcare professionals, influenza, policy,
• MeSH
• chřipka lidská prevence a kontrola   MeSH
• kojenec MeSH
• lidé středního věku MeSH
• lidé MeSH
• očkovací programy organizace a řízení   statistika a číselné údaje   MeSH
• pokrytí očkováním statistika a číselné údaje   MeSH
• předškolní dítě MeSH
• roční období MeSH
• senioři MeSH
• těhotenství MeSH
• zdravotní politika * MeSH
• zdravotnické plány - realizace organizace a řízení   statistika a číselné údaje   MeSH
• Check Tag
• kojenec MeSH
• lidé středního věku MeSH
• lidé MeSH
• předškolní dítě MeSH
• senioři MeSH
• těhotenství MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Evropa MeSH

Routine vaccination of certain groups of persons, including children and the elderly might provide additional protection to persons at risk for influenza complications and reduce the overall influenza burden. The aim of the paper was to estimate the influenza vaccine coverage in persons aged 0-4 years and > 65 years in Poland in 2004-2007. Official data collected by National Institute of Hygiene, National Institute of Public Health and Central Statistical Office were analyzed. Among vaccinations performed in all persons, the percentage of vaccinations performed in children aged 0-4 years varied from 1.6% to 2.0%. The estimated vaccination coverage in this age group of population was < 2%. Among persons aged > 65 years the influenza vaccine coverage increased from 7% in 2004 to 14% in 2007. Subjects aged > 65 years represented 25-36% of all vaccinated individuals. The influenza vaccination rates among age-related risk groups in Poland remain low. No or very low increase in a total vaccination coverage rates, as demonstrated in our paper, indicates that meeting the WHO targets concerning influenza vaccination coverage will be very difficult, if no further action is taken concerning vaccine uptake.

• MeSH
• kojenec MeSH
• lidé MeSH
• novorozenec MeSH
• pacientův souhlas se zdravotní péčí statistika a číselné údaje   MeSH
• předškolní dítě MeSH
• rizikové faktory MeSH
• senioři MeSH
• surveillance populace MeSH
• vakcinace statistika a číselné údaje   MeSH
• vakcíny proti chřipce aplikace a dávkování   MeSH
• věkové rozložení MeSH
• Check Tag
• kojenec MeSH
• lidé MeSH
• novorozenec MeSH
• předškolní dítě MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Polsko epidemiologie   MeSH
• Názvy látek
• vakcíny proti chřipce MeSH

Background Childhood vaccination rates fluctuate over time and do not always meet the levels recommended by the WHO. Objective This study aims to provide an overview of measures countries have introduced to increase vaccination rates. Methods We developed a structured data collection template that was completed by country experts from Europe, Israel, the USA, and Canada. Experts were identified using the European Observatory on Health Systems and Policies' HSPM (Health Systems and Policy Monitor) network. We approached experts from 32 countries and received responses from 22 countries. In the template we asked for measures introduced between 2014 and 2019. The experts were asked to indicate the type of intervention, the target population, possible positive and negative effects, and evidence on effectiveness. The information was collected between September 2019 and January 2020. Results We identified four main types of interventions: restrictive measures for the unvaccinated, financial incentives, measures supporting the logistics of vaccination, and vaccination promotion campaigns. Restrictive measures often involved expanding existing mandatory vaccination policies or limiting access to pre-school activities for unvaccinated children. Financial incentives for healthcare providers showed some positive effects. Regarding logistical support, several countries used schools as alternative vaccination sites, though this presented organisational challenges. Many countries invested in improving knowledge among both healthcare professionals and parents to encourage vaccine uptake. Conclusions Most initiatives implemented in the countries covered focussed on communication and knowledge enhancement. However, there is limited evidence on the impact of these measures on vaccination coverage.

• MeSH
• dítě MeSH
• internacionalita MeSH
• lidé MeSH
• očkovací programy * MeSH
• podpora zdraví * metody   MeSH
• pokrytí očkováním * statistika a číselné údaje   MeSH
• vakcinace * statistika a číselné údaje   MeSH
• zdravotní politika MeSH
• Check Tag
• dítě MeSH
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• přehledy MeSH
• srovnávací studie MeSH
• Geografické názvy
• Evropa MeSH
• Izrael MeSH
• Kanada MeSH
• Spojené státy americké MeSH

OBJECTIVES: Individuals with HIV infection are at an increased risk for a number of infectious diseases, some of which are preventable by vaccination. Unfortunately, little is known about the attitudes of this population group to vaccination, therefore, we decided to find out vaccination coverage against 5 infections among newly diagnosed HIV-infected patients in the Czech Republic. METHODS: This cross-sectional study was conducted on newly diagnosed patients who started their follow-up care at the HIV Clinic of Na Bulovce Hospital during the two following years. Vaccination history data and results of serological tests were collected from all participants. RESULTS: Enrolled were 269 HIV-positive subjects (94.1% males) with a mean age of 34.4 years, 64 subjects (23.8%) had tertiary education, 229 (85.1%) were men having sex with men, 32 (11.9%) were heterosexual, and 8 (3.0%) were injection drug users. The mean CD4+ T-lymphocyte count was 556.2/µL, with 149 persons (55.4%) who had a CD4+ T-lymphocyte count > 500/µL, and 68 (25.3%) individuals were late presenters with CD4+ T-lymphocyte count < 350/µL. A vaccination against tetanus was reported by 262 subjects (97.4%), against influenza by 18 subjects (6.7%), against tick-borne encephalitis by 18 subjects (6.7%), against viral hepatitis A by 78 persons (29.0%), and against hepatitis B by 104 subjects (38.7%). For influenza, tick-borne encephalitis and hepatitis A, a significant positive impact of tertiary education was found (p-values < 0.001-0.044). Vaccination coverage against both types of hepatitis was significantly lower in late presenters (p = 0.044 and p = 0.004, respectively). CONCLUSIONS: Vaccination rates found in our cohort were except tetanus and hepatitis B in young people low, especially for influenza and tick-borne encephalitis. Higher level of education and less advanced HIV infection were associated with higher vaccination rates. To improve this unsatisfactory situation, more attention should be paid to vaccination.

• Klíčová slova
• HIV, hepatitis, influenza, tetanus, tick-borne encephalitis, vaccination coverage,
• MeSH
• dospělí MeSH
• HIV infekce * diagnóza   MeSH
• lidé MeSH
• mladiství MeSH
• počet CD4 lymfocytů metody   MeSH
• pokrytí očkováním * MeSH
• průřezové studie MeSH
• Check Tag
• dospělí MeSH
• lidé MeSH
• mladiství MeSH
• mužské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH

• Klíčová slova
• COVID-19, Influenza vaccination, SARS-CoV-2, coverage rates, influenza,
• MeSH
• chřipka lidská * epidemiologie   prevence a kontrola   MeSH
• COVID-19 * MeSH
• lidé MeSH
• pandemie prevence a kontrola   MeSH
• pokrytí očkováním MeSH
• roční období MeSH
• SARS-CoV-2 MeSH
• vakcinace MeSH
• vakcíny proti chřipce * MeSH
• Check Tag
• lidé MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Austrálie epidemiologie   MeSH
• Názvy látek
• vakcíny proti chřipce * MeSH

We studied the incidence of invasive pneumococcal disease (IPD) in the Czech Republic by analysing two sources of data. The incidence of pneumococcal meningitis based on routine notification data varied between 0.4 and 0.6/100 000 population between 1997 and 2006. The incidence of IPD based on laboratory surveillance varied between 2.3 and 4.3/100 000 population between 2000 and 2006. The annual IPD incidence remained stable during the study period. Estimates of absolute IPD case-load in the entire country varied from 235 to 437 per year. The age-specific incidence was highest in the <1 year age group, reaching 4.3/100 000 for pneumococcal meningitis in routine notification and 15.7/100 000 for IPD in laboratory-based surveillance data, respectively. A total of 1236 Streptococcus pneumoniae isolates from cerebrospinal fluid and sterile body sites were investigated. The most frequent serotypes causing IPD in all ages were 3, 4, 14, 8 and 19F, accounting for 41.5% of all isolates. The most frequent serotypes by age group were: <1 year (6B and 19F); 1-4 years (14, 6B and 23F); 40-64 years (3, 8 and 4), and > or = 65 years (3, 4, 9N and 14). The coverage of serotypes in all age groups by pneumococcal vaccines ranged from 41.5% for 7-valent conjugate vaccine to 67.9% for 13-valent conjugate vaccine. The coverage of serotypes causing IPD is significantly different between infants/children and adults/elderly. PCV-7 coverage by age group was: <1 year (66.0%), 1-4 years (65.1%), 40-64 years (34.4%) and > or = 65 years (39.3%). Similar age differences between infants/children and adults/elderly were found in coverage by PCV-9, PCV-11 and PCV-13. The distribution of serotypes in the total population and individual age groups was stable during the period 2000-2006.

• MeSH
• dítě MeSH
• dospělí MeSH
• hlášení nemocí MeSH
• incidence MeSH
• kojenec MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• novorozenec MeSH
• pneumokoková meningitida epidemiologie   imunologie   mikrobiologie   prevence a kontrola   MeSH
• pneumokokové infekce epidemiologie   imunologie   mikrobiologie   prevence a kontrola   MeSH
• pneumokokové vakcíny aplikace a dávkování   MeSH
• předškolní dítě MeSH
• senioři MeSH
• sérotypizace MeSH
• Streptococcus pneumoniae klasifikace   imunologie   MeSH
• věkové rozložení MeSH
• Check Tag
• dítě MeSH
• dospělí MeSH
• kojenec MeSH
• lidé středního věku MeSH
• lidé MeSH
• mladiství MeSH
• mladý dospělý MeSH
• novorozenec MeSH
• předškolní dítě MeSH
• senioři MeSH
• Publikační typ
• časopisecké články MeSH
• práce podpořená grantem MeSH
• Geografické názvy
• Česká republika epidemiologie   MeSH
• Názvy látek
• pneumokokové vakcíny MeSH

OBJECTIVES: Seasonal influenza vaccination rates among the elderly in the Czech Republic are alarmingly low, making it one of the least vaccinated countries in Europe. This study explored the role of vaccine literacy and insurance coverage on vaccination status. METHODS: An analytical cross-sectional study was conducted in Summer 2023 using a self-administered questionnaire covering vaccine literacy (functional, interactive, and critical skills), negative perceptions towards influenza vaccination, and the 5C model (confidence, complacency, constraints, calculation, and collective responsibility). Individuals aged 55 and older were included in the study. Mediation analyses assessed the indirect effects of insurance coverage on vaccination status. RESULTS: Significant differences were noted in vaccination rates based on insurance coverage, chronic diseases, regular medication use, and previous COVID-19 and pneumococcal vaccinations. Vaccine literacy, especially interactive and critical skills, was higher among vaccinated individuals. Confidence and collective responsibility were significant promoters, while complacency and constraints were barriers to vaccination. Mediation analyses indicated that negative perceptions, confidence, and collective responsibility significantly mediated the relationship between insurance coverage and vaccination status. CONCLUSION: Enhancing vaccine literacy and addressing psychological antecedents are crucial for improving influenza vaccination rates among the elderly. Policy measures should include improving vaccine literacy, building public confidence, and addressing negative perceptions.

• Klíčová slova
• Czech Republic, aged, health literacy, influenza, vaccination hesitancy,
• MeSH
• chřipka lidská * prevence a kontrola   MeSH
• lidé středního věku MeSH
• lidé MeSH
• odkládání očkování * psychologie   MeSH
• pojistné krytí MeSH
• průřezové studie MeSH
• průzkumy a dotazníky MeSH
• roční období MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• vakcinace psychologie   statistika a číselné údaje   MeSH
• vakcíny proti chřipce * MeSH
• Východoevropané MeSH
• zdraví - znalosti, postoje, praxe MeSH
• zdravotní gramotnost * MeSH
• Check Tag
• lidé středního věku MeSH
• lidé MeSH
• mužské pohlaví MeSH
• senioři nad 80 let MeSH
• senioři MeSH
• ženské pohlaví MeSH
• Publikační typ
• časopisecké články MeSH
• Geografické názvy
• Česká republika MeSH
• Názvy látek
• vakcíny proti chřipce * MeSH