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Two cases with discrepancy in the quantitative cytological assessment of cerebrospinal fluid in neonatal samples using light microscopy in comparison with Sysmex XN-1000

P. Broz, S. Kukralova, J. Palatova, K. Kolduskova, J. Zenkova, D. Rajdl, J. Racek

. 2024 ; 34 (2) : 020802. [pub] 20240415

Jazyk angličtina Země Chorvatsko

Typ dokumentu kazuistiky, srovnávací studie

Perzistentní odkaz   https://www.medvik.cz/link/bmc24013505

We present two cases from the neonatal department with cerebrospinal fluid examination. We revealed a striking discrepancy in polymorphonuclear (PMN) and mononuclear (MN) cell counts using conventional light microscopy in comparison with automated analyzer Sysmex XN-1000 (PMNs - 13 vs. 173x106/L, MNs - 200 vs. 67x106/L in case 1 and PMNs - 13 vs. 372x106/L, MNs - 411 vs. 179x106/L in case 2). We revealed the dominant presence of hemosiderophages in both cases in cytospin slide. Even though Sysmex XN-1000 offers fast examination with a low sample volume, there is possibility of misdiagnosis, with negative impact on the patient.

Citace poskytuje Crossref.org

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