Occurrence of itraconazole-tolerant micromycetes in the soil and food products
Language English Country United States Media print
Document type Journal Article
PubMed
11097027
DOI
10.1007/bf02825661
Knihovny.cz E-resources
- MeSH
- Drug Resistance, Microbial MeSH
- Antifungal Agents pharmacology MeSH
- Fungi drug effects isolation & purification pathogenicity MeSH
- Itraconazole pharmacology MeSH
- Zea mays microbiology MeSH
- Humans MeSH
- Microbial Sensitivity Tests MeSH
- Mycoses drug therapy microbiology MeSH
- Opportunistic Infections drug therapy microbiology MeSH
- Food Microbiology * MeSH
- Soil Microbiology * MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Antifungal Agents MeSH
- Itraconazole MeSH
Unexpected pathogens from the environment represent considerable risk for humans with impaired health. We examined the occurrence of itraconazole tolerant micromycetes in soil and in maize products. Five concentrations of itraconazole (2.5-12.5 micrograms/mL) selected according to known treatment schedules for human patients were incorporated into Sabouraud agar with chloramphenicol and Rose Bengal and diluted samples were inoculated onto the agar surface. After 7-d growth at 22 degrees C colonies of Alternaria sp., Aspergillus clavatus, A. glaucus group, A. flavus, A. fumigatus, A. niger group, A. ochraceus group, A. ochraceus, Chaetomium sp., Cladosporium cladosporioides, Cylindrocarpon sp., Doratomyces sp., Fusarium sp., F. moniliforme, F. oxysporum, F. solani, F. subglutinans, Marianaea elegans, Mortierella sp., Mucor sp., Myrothecium sp., Penicillium sp., Rhizopus sp., Scopulariopsis brevicaulis, Sepedonium sp., Stachybotrys chartarum, Stemphylium sp., Torula humicola and Trichoderma viride were isolated.
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