5-Lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents
Jazyk angličtina Země Spojené arabské emiráty Médium print
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
- MeSH
- antagonisté leukotrienů farmakologie MeSH
- antiastmatika farmakologie MeSH
- antiflogistika farmakologie MeSH
- arachidonát-5-lipoxygenasa metabolismus MeSH
- inhibitory lipoxygenas MeSH
- kyselina arachidonová metabolismus MeSH
- leukotrieny biosyntéza MeSH
- lidé MeSH
- substrátová specifita MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- antagonisté leukotrienů MeSH
- antiastmatika MeSH
- antiflogistika MeSH
- arachidonát-5-lipoxygenasa MeSH
- inhibitory lipoxygenas MeSH
- kyselina arachidonová MeSH
- leukotrieny MeSH
Leukotrienes play an important role in the inflammatory process accompanying allergic diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are generated from arachidonic acid as a result of the 5-lipoxygenase action. This paper deals with 5-lipoxygenase action mechanism and the following biosynthesis of all leukotrienes. In this article, potential antileukotrienic agents are classified according to their mechanism of action. The original antileukotrienic compounds of the Research Institute for Pharmacy and Biochemistry in Prague (VUFB), Czech Republic are presented in a separate chapter of the paper.
Citace poskytuje Crossref.org
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