5-Lipoxygenase, leukotrienes biosynthesis and potential antileukotrienic agents
Language English Country United Arab Emirates Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
- MeSH
- Leukotriene Antagonists pharmacology MeSH
- Anti-Asthmatic Agents pharmacology MeSH
- Anti-Inflammatory Agents pharmacology MeSH
- Arachidonate 5-Lipoxygenase metabolism MeSH
- Lipoxygenase Inhibitors MeSH
- Arachidonic Acid metabolism MeSH
- Leukotrienes biosynthesis MeSH
- Humans MeSH
- Substrate Specificity MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Leukotriene Antagonists MeSH
- Anti-Asthmatic Agents MeSH
- Anti-Inflammatory Agents MeSH
- Arachidonate 5-Lipoxygenase MeSH
- Lipoxygenase Inhibitors MeSH
- Arachidonic Acid MeSH
- Leukotrienes MeSH
Leukotrienes play an important role in the inflammatory process accompanying allergic diseases of respiratory, gastrointestinal and dermatological systems. Leukotrienes are generated from arachidonic acid as a result of the 5-lipoxygenase action. This paper deals with 5-lipoxygenase action mechanism and the following biosynthesis of all leukotrienes. In this article, potential antileukotrienic agents are classified according to their mechanism of action. The original antileukotrienic compounds of the Research Institute for Pharmacy and Biochemistry in Prague (VUFB), Czech Republic are presented in a separate chapter of the paper.
References provided by Crossref.org
Anticancer Applications of Essential Oils Formulated into Lipid-Based Delivery Nanosystems
Chronic Inflammatory Diseases, Anti-Inflammatory Agents and Their Delivery Nanosystems
Investigation of Anti-Inflammatory Potential of N-Arylcinnamamide Derivatives
Investigating biological activity spectrum for novel styrylquinazoline analogues
