Human biomonitoring in the Czech Republic: an overview
Language English Country Germany Media print-electronic
Document type Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
PubMed
22014893
DOI
10.1016/j.ijheh.2011.09.007
PII: S1438-4639(11)00159-3
Knihovny.cz E-resources
- MeSH
- Biomarkers blood urine MeSH
- Hydrocarbons, Chlorinated blood urine MeSH
- Chromosome Aberrations chemically induced MeSH
- Cytogenetics MeSH
- Child MeSH
- Adult MeSH
- Epidemiological Monitoring MeSH
- Smoking blood epidemiology urine MeSH
- Middle Aged MeSH
- Humans MeSH
- Urban Population MeSH
- Adolescent MeSH
- Young Adult MeSH
- Milk chemistry MeSH
- Environmental Monitoring methods MeSH
- Pesticides blood urine MeSH
- Cross-Sectional Studies MeSH
- Surveys and Questionnaires MeSH
- Sex Distribution MeSH
- Selenium blood urine MeSH
- Metals, Heavy blood urine MeSH
- Age Distribution MeSH
- Environmental Exposure analysis MeSH
- Animals MeSH
- Check Tag
- Child MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Adolescent MeSH
- Young Adult MeSH
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Geographicals
- Czech Republic epidemiology MeSH
- Names of Substances
- Biomarkers MeSH
- Hydrocarbons, Chlorinated MeSH
- Pesticides MeSH
- Selenium MeSH
- Metals, Heavy MeSH
In the Czech Republic, the Human Biomonitoring Project (CZ-HBM) was launched in 1994 as an integral part of the nationwide Environmental Health Monitoring System (EHMS). Until now, the HBM covers two time periods: the first covered 1994-2003 and the second, 2005-2009. Altogether three population groups were included in the HBM: adults (blood donors aged 18-58 years), children aged 8-10 years, and breastfeeding primiparas. Sampling is organized on a yearly basis. Altogether three groups of biomarkers were analyzed: (a) selected heavy metals (Pb, Cd, Hg) and essential elements (Cu, Se, Zn) in blood and urine of adults and children, (b) indicator PCBs, DDT, DDE, HCB and HCHs in human milk and blood serum of adults and (c) cytogenetic changes in peripheral lymphocytes in blood of adults and children. This paper is focused on the general design of the CZ-HBM, the trends over time, and reference values. A significant downward time trend was observed for the blood lead levels in adults and children. Increased urinary cadmium levels were observed in Czech children compared to German children. The blood and urinary mercury levels were higher in women than in men. The levels of indicator PCB congeners in the Czech human milk samples were still higher than in most other European countries, because of existing hot spots. The levels of organochlorine pesticides showed a substantial continuous downward trend.
References provided by Crossref.org
Urinary stones as a novel matrix for human biomonitoring of toxic and essential elements
