In vitro selective inhibitory effect of 8-hydroxyquinoline against bifidobacteria and clostridia
Language English Country England, Great Britain Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23770542
DOI
10.1016/j.anaerobe.2013.05.008
PII: S1075-9964(13)00089-9
Knihovny.cz E-resources
- Keywords
- 8-Quinolinol, Antimicrobial activity, Bifidobacterium, Clostridium, Selectivity,
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Bifidobacterium drug effects isolation & purification MeSH
- Clostridium drug effects isolation & purification MeSH
- Feces microbiology MeSH
- Infant MeSH
- Humans MeSH
- Microbial Sensitivity Tests MeSH
- Oxyquinoline pharmacology MeSH
- Check Tag
- Infant MeSH
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Oxyquinoline MeSH
8-Hydroxyquinoline (8HQ) inhibited Clostridium tertium, Clostridium clostridioforme, Clostridium difficile and Clostridium perfringens in vitro with MICs of 8, 16, 32 and 32 μg/mL, respectively. In contrast, MICs of most bifidobacteria (84%) were 512 μg/mL or higher. Thus, 8HQ could be used as anti-clostridial agent or in selective media for bifidobacteria isolation.
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