Telomere binding protein TRB1 is associated with promoters of translation machinery genes in vivo
Jazyk angličtina Země Nizozemsko Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
26597966
DOI
10.1007/s11103-015-0409-8
PII: 10.1007/s11103-015-0409-8
Knihovny.cz E-zdroje
- Klíčová slova
- Arabidopsis thaliana, ChIP-seq, Ribosome, Telomere repeat binding (TRB), Translation machinery, snoRNA,
- MeSH
- Arabidopsis genetika metabolismus MeSH
- genová knihovna MeSH
- histony metabolismus MeSH
- molekulární sekvence - údaje MeSH
- nukleotidové motivy MeSH
- promotorové oblasti (genetika) genetika MeSH
- proteiny huseníčku genetika metabolismus MeSH
- proteiny vázající telomery genetika metabolismus MeSH
- proteosyntéza MeSH
- ribozomy genetika MeSH
- sekvence nukleotidů MeSH
- sekvenční analýza DNA MeSH
- sekvenční analýza hybridizací s uspořádaným souborem oligonukleotidů MeSH
- telomery metabolismus MeSH
- vazba proteinů MeSH
- výpočetní biologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- histony MeSH
- proteiny huseníčku MeSH
- proteiny vázající telomery MeSH
- TRB1 protein, Arabidopsis MeSH Prohlížeč
Recently we characterised TRB1, a protein from a single-myb-histone family, as a structural and functional component of telomeres in Arabidopsis thaliana. TRB proteins, besides their ability to bind specifically to telomeric DNA using their N-terminally positioned myb-like domain of the same type as in human shelterin proteins TRF1 or TRF2, also possess a histone-like domain which is involved in protein-protein interactions e.g., with POT1b. Here we set out to investigate the genome-wide localization pattern of TRB1 to reveal its preferential sites of binding to chromatin in vivo and its potential functional roles in the genome-wide context. Our results demonstrate that TRB1 is preferentially associated with promoter regions of genes involved in ribosome biogenesis, in addition to its roles at telomeres. This preference coincides with the frequent occurrence of telobox motifs in the upstream regions of genes in this category, but it is not restricted to the presence of a telobox. We conclude that TRB1 shows a specific genome-wide distribution pattern which suggests its role in regulation of genes involved in biogenesis of the translational machinery, in addition to its preferential telomeric localization.
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Mol Cell. 2002 Mar;9(3):493-503 PubMed
Genome. 2004 Apr;47(2):316-24 PubMed
Curr Biol. 1998 Jul 2;8(14):R492-4 PubMed
FEBS Lett. 2000 Oct 13;483(1):43-6 PubMed
Plant Mol Biol. 2006 Jan;60(1):69-85 PubMed
Plant Sci. 2014 Jun;223:134-45 PubMed
Biochem J. 2009 Apr 1;419(1):221-8, 2 p following 228 PubMed
J Cell Biol. 2000 Oct 30;151(3):653-62 PubMed
Phytochemistry. 2008 Jun;69(9):1814-9 PubMed
Genes Genet Syst. 2002 Feb;77(1):63-7 PubMed
Structure. 2001 Dec;9(12):1237-51 PubMed
Mol Biosyst. 2011 Apr;7(4):1013-23 PubMed
Curr Biol. 2008 Oct 14;18(19):1489-94 PubMed
EMBO Rep. 2005 Jan;6(1):39-45 PubMed
Nat Methods. 2012 Mar 04;9(4):357-9 PubMed
Oncogene. 2003 Oct 2;22(43):6690-8 PubMed
Nat Genet. 2005 Feb;37(2):193-7 PubMed
Curr Genet. 2003 Nov;44(2):73-84 PubMed
Trends Plant Sci. 2008 Jul;13(7):335-42 PubMed
Plant J. 1999 Dec;20(5):553-61 PubMed
Plant Cell. 2014 Jun 16;26(6):2351-2366 PubMed
Eur J Hum Genet. 2002 Feb;10(2):107-12 PubMed
Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):73-78 PubMed
Mol Biol Cell. 2005 Jan;16(1):260-9 PubMed
Chromosoma. 2012 Oct;121(5):465-74 PubMed
EMBO J. 2011 May 18;30(10):1928-38 PubMed
Chromosome Res. 2014 Jun;22(2):153-66 PubMed
Genes Dev. 2005 Sep 15;19(18):2100-10 PubMed
EMBO J. 2010 Mar 3;29(5):924-33 PubMed
BMC Bioinformatics. 2005 Jul 05;6:168 PubMed
Chromosome Res. 2005;13(5):469-79 PubMed
Plant Mol Biol. 1990 Jan;14(1):107-10 PubMed
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D633-6 PubMed
Plant Cell. 2008 Oct;20(10):2559-70 PubMed
Nucleic Acids Res. 2004 Mar 19;32(5):1792-7 PubMed
FEBS Lett. 2008 Apr 30;582(10):1400-6 PubMed
PLoS Genet. 2007 Jun;3(6):e86 PubMed
Mol Cell. 2014 Mar 20;53(6):954-64 PubMed
Bioinformatics. 2014 Sep 15;30(18):2568-75 PubMed
BMC Bioinformatics. 2012 Aug 10;13:199 PubMed
Bioessays. 2005 Jul;27(7):685-97 PubMed
Genome Biol. 2008;9(9):R137 PubMed
Cell Res. 2011 Jul;21(7):1028-38 PubMed
Plant J. 2010 Feb;61(4):637-49 PubMed
Cell. 2009 Jul 10;138(1):90-103 PubMed
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14584-9 PubMed
Protein Sci. 2005 Jan;14(1):119-30 PubMed
Nat Cell Biol. 2010 Aug;12(8):758-67 PubMed
Nucleic Acids Res. 2002 Jan 1;30(1):207-10 PubMed
Mol Cell. 2012 Sep 28;47(6):839-50 PubMed
BMC Plant Biol. 2010 Dec 20;10:283 PubMed
J Cell Sci. 2007 Oct 15;120(Pt 20):3678-87 PubMed
Nucleic Acids Res. 2011 May;39(10):4202-19 PubMed
Plant J. 2003 Mar;33(6):957-66 PubMed
Chromosoma. 1997 Jun;105(7-8):407-17 PubMed
Plant J. 2014 Mar;77(5):770-81 PubMed
Trends Cell Biol. 2005 Feb;15(2):84-91 PubMed
Curr Protein Pept Sci. 2011 Mar;12(2):75-83 PubMed
Genes Dev. 2012 Aug 1;26(15):1703-13 PubMed
Plant J. 2004 Sep;39(5):776-89 PubMed
Plant J. 2015 Jul;83(1):18-37 PubMed
FEBS Lett. 2004 Dec 17;578(3):311-5 PubMed
Genome Biol. 2003;4(4):R28 PubMed
Bioinformatics. 2010 Sep 1;26(17):2101-8 PubMed
Nucleic Acids Res. 1990 Oct 25;18(20):6097-100 PubMed
Plant Physiol. 2003 Nov;133(3):1336-50 PubMed
Trends Genet. 2000 Feb;16(2):51-3 PubMed
BMC Genomics. 2014 Apr 15;15:284 PubMed
Science. 2012 May 4;336(6081):593-7 PubMed
Nat Cell Biol. 2010 Aug;12(8):768-80 PubMed
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