BACKGROUND: Although type 1 diabetes (T1D) remains the most frequent form of diabetes in individuals aged less than 20 years at onset, other forms of diabetes are being increasingly recognized. OBJECTIVES: To describe the population of children with other forms of diabetes (non-type 1) included in the multinational SWEET (Better control in Pediatric and Adolescent diabeteS: Working to crEate CEnTers of Reference) database for children with diabetes. METHODS: Cases entered in the SWEET database are identified by their physician as T1D, type 2 diabetes (T2D) and other types of diabetes according to the ISPAD classification. Etiologic subgroups are provided for other types of diabetes. Descriptive analyses were tabulated for age at onset, gender, daily insulin doses, and hemoglobin A1c (A1C) for each type and subtype of diabetes and when possible, values were compared. RESULTS: Of the 27 104 patients included in this report, 95.5% have T1D, 1.3% T2D, and 3.2% other forms of diabetes. The two most frequent etiologies for other forms of diabetes were maturity onset diabetes of the young (MODY) (n = 351) and cystic fibrosis-related diabetes (CFRD) (n = 193). The cause was unknown or unreported in 10% of other forms of diabetes. Compared with T1D, children with T2D and CFRD were diagnosed at an older age, took less insulin and had lower A1C (all P < .0001). CONCLUSION: In centers included in SWEET, forms of diabetes other than type 1 remain rare and at times difficult to characterize. Sharing clinical information and outcome between SWEET centers on those rare forms of diabetes has the potential to improve management and outcome.

Alberta Children's Hospital Research Institute University of Calgary Calgary Canada

Associação Protectora dos Diabéticos de Portugal Lisbon Portugal

Centro de Diabetes de Curitiba Paraná Brazil

Children's University Hospital Children's Endocrinology Centre Riga Stradins University Riga Latvia

Departement of endocrinology diabetes and metabolic diseases University Childrens hospital University medical centre Ljubljana Slovenia

Department of Development and Regeneration KU Leuven Leuven Belgium

Department of Paediatrics University Hospital Motol and 2nd Faculty of Medicine Charles University Prague Prague Czech Republic

Department of Pediatrics Aarhus University Hospital Aarhus Denmark

Department of Pediatrics P and A Kyriakou Children's Hospital Diabetes Centre Athens Greece

Department of Pediatrics University Hospitals Leuven Leuven Belgium

Diabetes and Endocrinology Care Clinique Pédiatrique Centre Hospitalier de Luxembourg Luxembourg Luxembourg

Division of Paediatric Endocrinology University Hospital Brussels Brussels Belgium

Faculté de médecine Paris Descartes Université Sorbonne Paris cité Paris France

German Center for Diabetes Research Munich Neuherberg Germany

Hospital Dona Estefânia Unit of Pediatric Endocrinology and Diabetes Lisbon Portugal

Institute of Endocrinology Lithuanian University of Health Sciences Medical Academy Kaunas Lithuania

Institute of Epidemiology and Medical Biometry ZIBMT University of Ulm Ulm Germany

Paediatric Endocrinology Department of Paediatrics and Child Health Cork University Hospital Cork Ireland

Service d'endocrinologie gynécologie et diabétologie pédiatrique Hôpital Universitaire Necker Enfants Malades Assistance publique Hôpitaux de Paris Paris France

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