New evolutionary insights into the non-enzymatic origin of RNA oligomers
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, přehledy, práce podpořená grantem
PubMed
27785893
DOI
10.1002/wrna.1400
Knihovny.cz E-zdroje
- MeSH
- lidé MeSH
- molekulární evoluce * MeSH
- oligonukleotidy metabolismus MeSH
- původ života * MeSH
- RNA metabolismus MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- oligonukleotidy MeSH
- RNA MeSH
We outline novel findings on the non-enzymatic polymerization of nucleotides under plausible prebiotic conditions and on the spontaneous onset of informational complexity in the founding molecule, RNA. We argue that the unique ability of 3', 5' cyclic guanosine monophosphate to form stacked architectures and polymerize in a self-sustained manner suggests that this molecule may serve as the 'seed of life' from which all self-replicating oligonucleotides can be derived via a logically complete sequence of simple events. WIREs RNA 2017, 8:e1400. doi: 10.1002/wrna.1400 For further resources related to this article, please visit the WIREs website.
Dipartimento di Scienze Ecologiche e Biologiche Università della Tuscia Viterbo Italy
Institute of Biophysics Academy of Sciences of the Czech Republic Brno Czech Republic
Citace poskytuje Crossref.org
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