Central European Institute of Technology and Medical Faculty Masaryk University Brno Czech Republic

Centre for Cardiovascular Surgery and Transplantation Brno

Department of Immunology 2 Faculty of Medicine Charles University and University Hospital Motol Prague

Department of Pediatric Hematology and Oncology 2 Faculty of Medicine Charles University and University Hospital Motol Prague

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Tummers B, Green DR. Caspase-8: regulating life and death. Immunol Rev. 2017(1);277:76–89. PubMed PMC

Su H, Bidere N, Zheng L, et al. Requirement for Caspase-8 in NF-kB activation by antigen receptor. Science. 2005;307(5714):1465–1468. PubMed

Moen SH, Westhrin M, Zahoor M, et al. Caspase-8 regulates the expression of pro- and anti-inflammatory cytokines in human bone marrow-derived mesenchymal stromal cells. Immunity, Inflamm Dis. 2016;4(3):327–337. PubMed PMC

Chun HJ, Zheng L, Ahmad M, et al. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutation lead to human immunodeficiency. Nature. 2002;419(6905):395–399. PubMed

Niemela J, Kuehn HS, Kelly C, et al. Caspase-8 deficiency presenting as late-onset multi-organ lymphocytic infiltration with granulomas in two adult siblings. J Clin Immunol. 2015;35(4):348–355. PubMed PMC

Keller N, Mares J, Zerbe O, Grütter MG. Structural and biochemical studies on Procaspase-8: new insights on initiator caspase activation. Structure. 2009;17(3):438–448. PubMed

Blanchard H, Donepudi M, Tschopp M, Kodandapani L, Wu JC, Grütter MG. Caspase-8 specificity probed at subsite S4: Crystal structure of the caspase-8-Z-DEVD-cho complex. J Mol Biol. 2000;302(1):9–16. PubMed

Boatright KM, Renatus M, Scott FL, et al. A unified model for apical caspase activation the cellular effects that distinguish apoptosis from other. Mol Cell. 2003;11(2):529–541. PubMed

Völkl S, Rensing-Ehl A, Allgäuer A, et al. Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome. Blood. 2016;128(2): 227–238. PubMed

Kennedy NJ, Kataoka T, Tschopp J, Budd RC. Caspase activation is required for T cell proliferation. J Exp Med. 1999;190(12):1891–1895. PubMed PMC

Feltham R, Vince JE, Lawlor KE. Caspase-8: not so silently deadly. Clin Transl Immunol. 2017;6(1):e124. PubMed PMC

Takahashi K, Kawai T, Kumar H, Sato S, Yonehara S, Akira S. Cutting edge: roles of Caspase-8 and Caspase-10 in innate immune responses to double-stranded RNA. J Immunol. 2006;176(8):4520–4524. PubMed

Piccioli D, Tavarini S, Borgogni E, et al. Functional specialization of human circulating CD16 and CD1c myeloid dendritic-cell subsets. Blood. 2007;109(12):5371–5379. PubMed

Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn's disease