Aryl Hydrocarbon Hydroxylases [aromatické hydroxylasy]

topical
80
Terms

AHH
aromatické hydroxylázy
aryl uhlovodíkové hydroxylázy
mikrosomální monooxygenasy
mikrozomální monooxygenázy
xenobiotické monooxygenasy
xenobiotické monooxygenázy

 

Microsomal Monooxygenases
Xenobiotic Monooxygenases

Persistent link   https://www.medvik.cz/link/D001189
Definition

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.

DUI
D001189 MeSH Browser
CUI
M0001774
Previous indexing
Hydroxylases (1971-1974); Polycyclic Hydrocarbons (1974)
History note
75
Public note
75

Allowable subheadings

AD
administration & dosage
AE
adverse effects
AN
analysis 4
AI
antagonists & inhibitors 9
BI
biosynthesis 4
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry 10
CL
classification
DF
deficiency
DE
drug effects 3
EC
economics
GE
genetics 36
HI
history
IM
immunology
IP
isolation & purification 4
ME
metabolism 46
PK
pharmacokinetics
PD
pharmacology
PH
physiology 4
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure 1
UR
urine

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.244 Cytochromes 121
D08.244.453 Cytochrome P-450 Enzyme System 692
D08.244.453.003 Cytochrome P-450 CYP2J2 2
D08.244.453.005 Aryl Hydrocarbon Hydroxylases 80
D08.244.453.005.050 Aniline Hydroxylase 1
D08.244.453.005.110 Benzopyrene Hydroxylase
D08.244.453.005.332 Cytochrome P-450 CYP1A1 172
D08.244.453.005.443 Cytochrome P-450 CYP1A2 72
D08.244.453.005.500 Cytochrome P-450 CYP1B1 9
D08.244.453.005.550 Cytochrome P-450 CYP2B1 4
D08.244.453.005.575 Cytochrome P-450 CYP2B6 9
D08.244.453.005.590 Cytochrome P-450 CYP2C8 8
D08.244.453.005.600 Cytochrome P-450 CYP2D6 119
D08.244.453.012 Camphor 5-Monooxygenase 1
D08.244.453.100 Cytochrome P450 Family 1 3
D08.244.453.484 Cytochrome P450 Family 11
D08.244.453.485 Cytochrome P450 Family 12 1
D08.244.453.487 Cytochrome P450 Family 17
D08.244.453.489 Cytochrome P450 Family 19 1
D08.244.453.491 Cytochrome P450 Family 2 4
D08.244.453.493 Cytochrome P450 Family 21
D08.244.453.496 Cytochrome P450 Family 24 1
D08.244.453.498 Cytochrome P450 Family 26
D08.244.453.499 Cytochrome P450 Family 27
D08.244.453.860 Cytochrome P450 Family 3 1
D08.244.453.870 Cytochrome P450 Family 4
D08.244.453.875 Cytochrome P450 Family 46
D08.244.453.878 Cytochrome P450 Family 51
D08.244.453.880 Cytochrome P450 Family 6
D08.244.453.890 Cytochrome P450 Family 7
D08.244.453.900 Cytochrome P450 Family 8
D08.244.453.915 Steroid Hydroxylases 16
D08.244.453.957 Trans-Cinnamate 4-Monooxygenase 1
D08.811 Enzymes 1 547
D08.811.682 Oxidoreductases 446
D08.811.682.690 Oxygenases 76
D08.811.682.690.708 Mixed Function Oxygenases 68
D08.811.682.690.708.170 Cytochrome P-450 Enzyme System 692
D08.811.682.690.708.170.005 Cytochrome P-450 CYP2J2 2
D08.811.682.690.708.170.010 Aryl Hydrocarbon Hydroxylases 80
D08.811.682.690.708.170.010.024 7-Alkoxycoumarin O-Dealkylase
D08.811.682.690.708.170.010.050 Aniline Hydroxylase 1
D08.811.682.690.708.170.010.110 Benzopyrene Hydroxylase
D08.811.682.690.708.170.010.277 Cytochrome P-450 CYP1A1 172
D08.811.682.690.708.170.010.443 Cytochrome P-450 CYP1A2 72
D08.811.682.690.708.170.010.500 Cytochrome P-450 CYP1B1 9
D08.811.682.690.708.170.010.550 Cytochrome P-450 CYP2B1 4
D08.811.682.690.708.170.010.575 Cytochrome P-450 CYP2B6 9
D08.811.682.690.708.170.010.590 Cytochrome P-450 CYP2C8 8
D08.811.682.690.708.170.010.600 Cytochrome P-450 CYP2D6 119
D08.811.682.690.708.170.012 Camphor 5-Monooxygenase 1
D08.811.682.690.708.170.020 Cytochrome P450 Family 1 3
D08.811.682.690.708.170.425 Cytochrome P450 Family 11
D08.811.682.690.708.170.438 Cytochrome P450 Family 12 1
D08.811.682.690.708.170.444 Cytochrome P450 Family 17
D08.811.682.690.708.170.447 Cytochrome P450 Family 19 1
D08.811.682.690.708.170.450 Cytochrome P450 Family 2 4
D08.811.682.690.708.170.463 Cytochrome P450 Family 21
D08.811.682.690.708.170.469 Cytochrome P450 Family 24 1
D08.811.682.690.708.170.485 Cytochrome P450 Family 26
D08.811.682.690.708.170.493 Cytochrome P450 Family 27
D08.811.682.690.708.170.495 Cytochrome P450 Family 3 1
D08.811.682.690.708.170.496 Cytochrome P450 Family 4
D08.811.682.690.708.170.497 Cytochrome P450 Family 46
D08.811.682.690.708.170.499 Cytochrome P450 Family 51
D08.811.682.690.708.170.880 Cytochrome P450 Family 6
D08.811.682.690.708.170.890 Cytochrome P450 Family 7
D08.811.682.690.708.170.900 Cytochrome P450 Family 8
D08.811.682.690.708.170.915 Steroid Hydroxylases 16
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 577
D12.776.422 Hemeproteins 16
D12.776.422.220 Cytochromes 121
D12.776.422.220.453 Cytochrome P-450 Enzyme System 692
D12.776.422.220.453.005 Cytochrome P-450 CYP2J2 2
D12.776.422.220.453.010 Aryl Hydrocarbon Hydroxylases 80
D12.776.422.220.453.010.050 Aniline Hydroxylase 1
D12.776.422.220.453.010.110 Benzopyrene Hydroxylase
D12.776.422.220.453.010.332 Cytochrome P-450 CYP1A1 172
D12.776.422.220.453.010.443 Cytochrome P-450 CYP1A2 72
D12.776.422.220.453.010.500 Cytochrome P-450 CYP1B1 9
D12.776.422.220.453.010.550 Cytochrome P-450 CYP2B1 4
D12.776.422.220.453.010.575 Cytochrome P-450 CYP2B6 9
D12.776.422.220.453.010.590 Cytochrome P-450 CYP2C8 8
D12.776.422.220.453.010.600 Cytochrome P-450 CYP2D6 119
D12.776.422.220.453.012 Camphor 5-Monooxygenase 1
D12.776.422.220.453.100 Cytochrome P450 Family 1 3
D12.776.422.220.453.484 Cytochrome P450 Family 11
D12.776.422.220.453.485 Cytochrome P450 Family 12 1
D12.776.422.220.453.487 Cytochrome P450 Family 17
D12.776.422.220.453.489 Cytochrome P450 Family 19 1
D12.776.422.220.453.491 Cytochrome P450 Family 2 4
D12.776.422.220.453.493 Cytochrome P450 Family 21
D12.776.422.220.453.496 Cytochrome P450 Family 24 1
D12.776.422.220.453.498 Cytochrome P450 Family 26
D12.776.422.220.453.499 Cytochrome P450 Family 27
D12.776.422.220.453.860 Cytochrome P450 Family 3 1
D12.776.422.220.453.870 Cytochrome P450 Family 4
D12.776.422.220.453.875 Cytochrome P450 Family 46
D12.776.422.220.453.878 Cytochrome P450 Family 51
D12.776.422.220.453.880 Cytochrome P450 Family 6
D12.776.422.220.453.890 Cytochrome P450 Family 7
D12.776.422.220.453.900 Cytochrome P450 Family 8
D12.776.422.220.453.915 Steroid Hydroxylases 16

4-chlorobiphenyl hydroxylase Chemical MeSH Browser

7,12-dimethylbenz(a)anthracene hydroxylase Chemical MeSH Browser

CYP1A4 protein, Gallus gallus Chemical MeSH Browser

CYP2A10 protein, Oryctolagus cuniculus Chemical MeSH Browser

CYP2A11 protein, Oryctolagus cuniculus Chemical MeSH Browser

CYP2A13 protein, human Chemical MeSH Browser

CYP2A7 protein, human Chemical MeSH Browser

CYP2A8 protein, Mesocricetus auratus Chemical MeSH Browser

CYP2C11 protein, rat Chemical MeSH Browser

CYP2C18 protein, human Chemical MeSH Browser

CYP2C3 protein, Oryctolagus cuniculus Chemical MeSH Browser

CYP2K1 protein, Oncorhynchus mykiss Chemical MeSH Browser

CYP3A43 protein, human Chemical MeSH Browser

CYP4F12 protein, human Chemical MeSH Browser

CYP4F8 protein, human Chemical MeSH Browser

Cyp2a1 protein, rat Chemical MeSH Browser

Cyp2a4 protein, mouse Chemical MeSH Browser

Cyp2a5 protein, mouse Chemical MeSH Browser

Cyp2b10 protein, mouse Chemical MeSH Browser

Cyp2b19 protein, mouse Chemical MeSH Browser

Cyp2b3 protein, rat Chemical MeSH Browser

Cyp2b9 protein, mouse Chemical MeSH Browser

Cyp2c40 protein, mouse Chemical MeSH Browser

Cyp2d2 protein, rat Chemical MeSH Browser

Cyp2d4 protein, rat Chemical MeSH Browser

Cyp3a62 protein, rat Chemical MeSH Browser

Cyp3a9 protein, rat Chemical MeSH Browser

Fmo-2 protein, Drosophila Chemical MeSH Browser

acetanilide hydroxylase Chemical MeSH Browser

aklavinone 11-hydroxylase Chemical MeSH Browser

biphenyl-2-hydroxylase Chemical MeSH Browser

biphenyl-3-hydroxylase Chemical MeSH Browser

biphenyl-4-hydroxylase Chemical MeSH Browser

chlorzoxazone 6-hydroxylase, rat Chemical MeSH Browser

cytochrome P-450 CYP1A3 (rainbow trout) Chemical MeSH Browser

cytochrome P-450 CYP1A5 Chemical MeSH Browser

cytochrome P-450 CYP2A16 (hamster) Chemical MeSH Browser

cytochrome P-450 CYP2B11 (dog) Chemical MeSH Browser

cytochrome P-450 CYP2B4 (rabbit) Chemical MeSH Browser

cytochrome P-450 CYP2B5 (rabbit) Chemical MeSH Browser

cytochrome P-450 CYP2D15 (dog) Chemical MeSH Browser

cytochrome P-450 CYP2D16 (guinea pig) Chemical MeSH Browser

cytochrome P-450 CYP2D19 (marmoset) Chemical MeSH Browser

cytochrome P-450 CYP2D30 (marmoset) Chemical MeSH Browser

cytochrome P-450 CYP2G1 Chemical MeSH Browser

cytochrome P-450 CYP3A14 (guinea pig) Chemical MeSH Browser

cytochrome P-450 CYP3A21 (marmoset) Chemical MeSH Browser

cytochrome P-450 CYP3A37 (chicken) Chemical MeSH Browser

cytochrome P-450 CYP3A6 (rabbit) Chemical MeSH Browser

cytochrome P-450 CYP3A65, zebrafish Chemical MeSH Browser

cytochrome P-450 CYP4A4 (rabbit) Chemical MeSH Browser

cytochrome P-450 CYP4B1 Chemical MeSH Browser

cytochrome P-450 CYP6B1 (butterfly) Chemical MeSH Browser

cytochrome P-450 CYP6B17, butterfly Chemical MeSH Browser

cytochrome P-450 CYP6B3 (butterfly) Chemical MeSH Browser

cytochrome P-450 CYP6B4, butterfly Chemical MeSH Browser

cytochrome P450 CYP3A10 (hamster) Chemical MeSH Browser

deoxysarpagine hydroxylase Chemical MeSH Browser

ecdysone 20-hydroxylase Chemical MeSH Browser

phenanthrene-9,10-epoxidase Chemical MeSH Browser

steroid 15-alpha-hydroxylase Chemical MeSH Browser

steroid 15-beta-hydroxylase Chemical MeSH Browser

steroid 16-beta-hydroxylase Chemical MeSH Browser

steroid hormone 7-alpha-hydroxylase Chemical MeSH Browser

testosterone 7-alpha-hydroxylase, hamster Chemical MeSH Browser

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