aromatické hydroxylasy [Aryl Hydrocarbon Hydroxylases]

tematický
80
Termíny

AHH
aromatické hydroxylázy
aryl uhlovodíkové hydroxylázy
mikrosomální monooxygenasy
mikrozomální monooxygenázy
xenobiotické monooxygenasy
xenobiotické monooxygenázy

 

Microsomal Monooxygenases
Xenobiotic Monooxygenases

Perzistentní odkaz   https://www.medvik.cz/link/D001189
Definice

Velká skupina cytochrom P-450 (hem-thiolát) monooxygenáz, které tvoří komplex s NADH-FMN-oxidoreduktázou při četných oxidacích aromatických sloučenin. Katalyzují hydroxylaci širokého spektra substrátů a jsou důležité v metabolismu steroidů, léků a toxinů, jako např. fenobarbital, karcinogeny a insekticidy.

A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.

DUI
D001189 MeSH Prohlížeč
CUI
M0001774
Předchozí užití
Hydroxylases (1971-1974); Polycyclic Hydrocarbons (1974)
Historická pozn.
75
Veřejná pozn.
75

Povolená podhesla

AN
analýza 4
AI
antagonisté a inhibitory 9
AD
aplikace a dávkování
BI
biosyntéza 4
CS
chemická syntéza
CH
chemie 10
HI
dějiny
EC
ekonomika
PK
farmakokinetika
PD
farmakologie
PH
fyziologie 4
GE
genetika 36
IM
imunologie
IP
izolace a purifikace 4
CL
klasifikace
BL
krev
ME
metabolismus 46
UR
moč
CF
mozkomíšní mok
DF
nedostatek
ST
normy
PO
otrava
AE
škodlivé účinky
TU
terapeutické užití
TO
toxicita
DE
účinky léků 3
RE
účinky záření
UL
ultrastruktura 1
SD
zásobování a distribuce

D Chemikálie a léčiva
D08 enzymy a koenzymy 7
D08.244 cytochromy 121
D08.244.453 systém (enzymů) cytochromů P-450 692
D08.244.453.003 cytochrom P-450 CYP2J2 2
D08.244.453.005 aromatické hydroxylasy 80
D08.244.453.005.050 anilinhydroxylasa 1
D08.244.453.005.110 benzopyrenhydroxylasa
D08.244.453.005.332 cytochrom P-450 CYP1A1 172
D08.244.453.005.443 cytochrom P-450 CYP1A2 72
D08.244.453.005.500 cytochrom P450 CYP1B1 9
D08.244.453.005.550 cytochrom P-450 CYP2B1 4
D08.244.453.005.575 cytochrom P450 CYP2B6 9
D08.244.453.005.590 cytochrom P450 CYP2C8 8
D08.244.453.005.600 cytochrom P-450 CYP2D6 119
D08.244.453.012 5-monooxygenasa kafru 1
D08.244.453.100 rodina 1 cytochromu P450 3
D08.244.453.484 rodina 11 cytochromu P450
D08.244.453.485 rodina 12 cytochromů P450 1
D08.244.453.487 rodina 17 cytochromů P450
D08.244.453.489 rodina 19 cytochromů P450 1
D08.244.453.491 rodina 2 cytochromů P450 4
D08.244.453.493 rodina 21 cytochromů P450
D08.244.453.496 rodina 24 cytochromů P450 1
D08.244.453.498 rodina 26 cytochromu P450
D08.244.453.499 rodina 27 cytochromů P450
D08.244.453.860 rodina 3 cytochromů P450 1
D08.244.453.870 rodina 4 cytochromů P450
D08.244.453.875 rodina 46 cytochromů P450
D08.244.453.878 rodina 51 cytochromů P450
D08.244.453.880 rodina 6 cytochromů P450
D08.244.453.890 rodina 7 cytochromů P450
D08.244.453.900 rodina 8 cytochromů P450
D08.244.453.915 steroidhydroxylasy 16
D08.244.453.957 4-monooxygenasa kyseliny skořicové 1
D08.811 enzymy 1 547
D08.811.682 oxidoreduktasy 446
D08.811.682.690 oxygenasy 76
D08.811.682.690.708 oxygenasy se smíšenou funkcí 68
D08.811.682.690.708.170 systém (enzymů) cytochromů P-450 692
D08.811.682.690.708.170.005 cytochrom P-450 CYP2J2 2
D08.811.682.690.708.170.010 aromatické hydroxylasy 80
D08.811.682.690.708.170.010.024 7-alkoxykumarin-O-dealkylasa
D08.811.682.690.708.170.010.050 anilinhydroxylasa 1
D08.811.682.690.708.170.010.110 benzopyrenhydroxylasa
D08.811.682.690.708.170.010.277 cytochrom P-450 CYP1A1 172
D08.811.682.690.708.170.010.443 cytochrom P-450 CYP1A2 72
D08.811.682.690.708.170.010.500 cytochrom P450 CYP1B1 9
D08.811.682.690.708.170.010.550 cytochrom P-450 CYP2B1 4
D08.811.682.690.708.170.010.575 cytochrom P450 CYP2B6 9
D08.811.682.690.708.170.010.590 cytochrom P450 CYP2C8 8
D08.811.682.690.708.170.010.600 cytochrom P-450 CYP2D6 119
D08.811.682.690.708.170.012 5-monooxygenasa kafru 1
D08.811.682.690.708.170.020 rodina 1 cytochromu P450 3
D08.811.682.690.708.170.425 rodina 11 cytochromu P450
D08.811.682.690.708.170.438 rodina 12 cytochromů P450 1
D08.811.682.690.708.170.444 rodina 17 cytochromů P450
D08.811.682.690.708.170.447 rodina 19 cytochromů P450 1
D08.811.682.690.708.170.450 rodina 2 cytochromů P450 4
D08.811.682.690.708.170.463 rodina 21 cytochromů P450
D08.811.682.690.708.170.469 rodina 24 cytochromů P450 1
D08.811.682.690.708.170.485 rodina 26 cytochromu P450
D08.811.682.690.708.170.493 rodina 27 cytochromů P450
D08.811.682.690.708.170.495 rodina 3 cytochromů P450 1
D08.811.682.690.708.170.496 rodina 4 cytochromů P450
D08.811.682.690.708.170.497 rodina 46 cytochromů P450
D08.811.682.690.708.170.499 rodina 51 cytochromů P450
D08.811.682.690.708.170.880 rodina 6 cytochromů P450
D08.811.682.690.708.170.890 rodina 7 cytochromů P450
D08.811.682.690.708.170.900 rodina 8 cytochromů P450
D08.811.682.690.708.170.915 steroidhydroxylasy 16
D12 aminokyseliny, peptidy a proteiny 16
D12.776 proteiny 2 577
D12.776.422 hemoproteiny 16
D12.776.422.220 cytochromy 121
D12.776.422.220.453 systém (enzymů) cytochromů P-450 692
D12.776.422.220.453.005 cytochrom P-450 CYP2J2 2
D12.776.422.220.453.010 aromatické hydroxylasy 80
D12.776.422.220.453.010.050 anilinhydroxylasa 1
D12.776.422.220.453.010.110 benzopyrenhydroxylasa
D12.776.422.220.453.010.332 cytochrom P-450 CYP1A1 172
D12.776.422.220.453.010.443 cytochrom P-450 CYP1A2 72
D12.776.422.220.453.010.500 cytochrom P450 CYP1B1 9
D12.776.422.220.453.010.550 cytochrom P-450 CYP2B1 4
D12.776.422.220.453.010.575 cytochrom P450 CYP2B6 9
D12.776.422.220.453.010.590 cytochrom P450 CYP2C8 8
D12.776.422.220.453.010.600 cytochrom P-450 CYP2D6 119
D12.776.422.220.453.012 5-monooxygenasa kafru 1
D12.776.422.220.453.100 rodina 1 cytochromu P450 3
D12.776.422.220.453.484 rodina 11 cytochromu P450
D12.776.422.220.453.485 rodina 12 cytochromů P450 1
D12.776.422.220.453.487 rodina 17 cytochromů P450
D12.776.422.220.453.489 rodina 19 cytochromů P450 1
D12.776.422.220.453.491 rodina 2 cytochromů P450 4
D12.776.422.220.453.493 rodina 21 cytochromů P450
D12.776.422.220.453.496 rodina 24 cytochromů P450 1
D12.776.422.220.453.498 rodina 26 cytochromu P450
D12.776.422.220.453.499 rodina 27 cytochromů P450
D12.776.422.220.453.860 rodina 3 cytochromů P450 1
D12.776.422.220.453.870 rodina 4 cytochromů P450
D12.776.422.220.453.875 rodina 46 cytochromů P450
D12.776.422.220.453.878 rodina 51 cytochromů P450
D12.776.422.220.453.880 rodina 6 cytochromů P450
D12.776.422.220.453.890 rodina 7 cytochromů P450
D12.776.422.220.453.900 rodina 8 cytochromů P450
D12.776.422.220.453.915 steroidhydroxylasy 16

4-chlorobiphenyl hydroxylase Chemical MeSH Prohlížeč

7,12-dimethylbenz(a)anthracene hydroxylase Chemical MeSH Prohlížeč

CYP1A4 protein, Gallus gallus Chemical MeSH Prohlížeč

CYP2A10 protein, Oryctolagus cuniculus Chemical MeSH Prohlížeč

CYP2A11 protein, Oryctolagus cuniculus Chemical MeSH Prohlížeč

CYP2A13 protein, human Chemical MeSH Prohlížeč

CYP2A7 protein, human Chemical MeSH Prohlížeč

CYP2A8 protein, Mesocricetus auratus Chemical MeSH Prohlížeč

CYP2C11 protein, rat Chemical MeSH Prohlížeč

CYP2C18 protein, human Chemical MeSH Prohlížeč

CYP2C3 protein, Oryctolagus cuniculus Chemical MeSH Prohlížeč

CYP2K1 protein, Oncorhynchus mykiss Chemical MeSH Prohlížeč

CYP3A43 protein, human Chemical MeSH Prohlížeč

CYP4F12 protein, human Chemical MeSH Prohlížeč

CYP4F8 protein, human Chemical MeSH Prohlížeč

Cyp2a1 protein, rat Chemical MeSH Prohlížeč

Cyp2a4 protein, mouse Chemical MeSH Prohlížeč

Cyp2a5 protein, mouse Chemical MeSH Prohlížeč

Cyp2b10 protein, mouse Chemical MeSH Prohlížeč

Cyp2b19 protein, mouse Chemical MeSH Prohlížeč

Cyp2b3 protein, rat Chemical MeSH Prohlížeč

Cyp2b9 protein, mouse Chemical MeSH Prohlížeč

Cyp2c40 protein, mouse Chemical MeSH Prohlížeč

Cyp2d2 protein, rat Chemical MeSH Prohlížeč

Cyp2d4 protein, rat Chemical MeSH Prohlížeč

Cyp3a62 protein, rat Chemical MeSH Prohlížeč

Cyp3a9 protein, rat Chemical MeSH Prohlížeč

Fmo-2 protein, Drosophila Chemical MeSH Prohlížeč

acetanilide hydroxylase Chemical MeSH Prohlížeč

aklavinone 11-hydroxylase Chemical MeSH Prohlížeč

biphenyl-2-hydroxylase Chemical MeSH Prohlížeč

biphenyl-3-hydroxylase Chemical MeSH Prohlížeč

biphenyl-4-hydroxylase Chemical MeSH Prohlížeč

chlorzoxazone 6-hydroxylase, rat Chemical MeSH Prohlížeč

cytochrome P-450 CYP1A3 (rainbow trout) Chemical MeSH Prohlížeč

cytochrome P-450 CYP1A5 Chemical MeSH Prohlížeč

cytochrome P-450 CYP2A16 (hamster) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2B11 (dog) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2B4 (rabbit) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2B5 (rabbit) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2D15 (dog) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2D16 (guinea pig) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2D19 (marmoset) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2D30 (marmoset) Chemical MeSH Prohlížeč

cytochrome P-450 CYP2G1 Chemical MeSH Prohlížeč

cytochrome P-450 CYP3A14 (guinea pig) Chemical MeSH Prohlížeč

cytochrome P-450 CYP3A21 (marmoset) Chemical MeSH Prohlížeč

cytochrome P-450 CYP3A37 (chicken) Chemical MeSH Prohlížeč

cytochrome P-450 CYP3A6 (rabbit) Chemical MeSH Prohlížeč

cytochrome P-450 CYP3A65, zebrafish Chemical MeSH Prohlížeč

cytochrome P-450 CYP4A4 (rabbit) Chemical MeSH Prohlížeč

cytochrome P-450 CYP4B1 Chemical MeSH Prohlížeč

cytochrome P-450 CYP6B1 (butterfly) Chemical MeSH Prohlížeč

cytochrome P-450 CYP6B17, butterfly Chemical MeSH Prohlížeč

cytochrome P-450 CYP6B3 (butterfly) Chemical MeSH Prohlížeč

cytochrome P-450 CYP6B4, butterfly Chemical MeSH Prohlížeč

cytochrome P450 CYP3A10 (hamster) Chemical MeSH Prohlížeč

deoxysarpagine hydroxylase Chemical MeSH Prohlížeč

ecdysone 20-hydroxylase Chemical MeSH Prohlížeč

phenanthrene-9,10-epoxidase Chemical MeSH Prohlížeč

steroid 15-alpha-hydroxylase Chemical MeSH Prohlížeč

steroid 15-beta-hydroxylase Chemical MeSH Prohlížeč

steroid 16-beta-hydroxylase Chemical MeSH Prohlížeč

steroid hormone 7-alpha-hydroxylase Chemical MeSH Prohlížeč

testosterone 7-alpha-hydroxylase, hamster Chemical MeSH Prohlížeč

Přidat

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