Factor XII [faktor XII]
- Terms
-
glass faktor
Hagemanův faktor
koagulační faktor XII
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Coagulation Factor XII
Factor 12
Factor Twelve
Hageman Factor
Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.
- DUI
- D005174 MeSH Browser
- CUI
- M0008158
- CAS
- Blood-coagulation factor XII
- History note
- 66(64)
- Public note
- 66
Combination
- deficiency
- Factor XII Deficiency
Allowable subheadings
- AD
- administration & dosage
- AE
- adverse effects 1
- AG
- agonists
- AN
- analysis 1
- AI
- antagonists & inhibitors 1
- BI
- biosynthesis
- CF
- cerebrospinal fluid
- CS
- chemical synthesis
- CH
- chemistry 1
- CL
- classification
- DE
- drug effects
- EC
- economics
- GE
- genetics
- HI
- history
- IM
- immunology
- IP
- isolation & purification 1
- ME
- metabolism 2
- PK
- pharmacokinetics
- PD
- pharmacology
- PH
- physiology 3
- PO
- poisoning
- RE
- radiation effects
- ST
- standards
- SD
- supply & distribution
- TU
- therapeutic use
- TO
- toxicity
- UL
- ultrastructure
- UR
- urine
factor XII Bern Chemical MeSH Browser
factor XII Locarno Chemical MeSH Browser
factor XII Mie-1, human Chemical MeSH Browser
factor XII Toronto Chemical MeSH Browser
factor XII Washington D.C. Chemical MeSH Browser