Protein C [protein C]

topical
111
Persistent link   https://www.medvik.cz/link/D011486
Definition

A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by inactivating factors Va and VIIIa at the rate-limiting steps of thrombin formation.

DUI
D011486 MeSH Browser
CUI
M0017852
Previous indexing
Blood Proteins (1966-1986); Glycoproteins (1966-1986)
History note
87
Public note
87

Combination

deficiency
Protein C Deficiency

Allowable subheadings

AD
administration & dosage 12
AE
adverse effects 1
AG
agonists 0
AA
analogs & derivatives 0
AN
analysis 14
AI
antagonists & inhibitors 1
BI
biosynthesis 0
CF
cerebrospinal fluid 0
CS
chemical synthesis 0
CH
chemistry 1
CL
classification 0
DE
drug effects 0
EC
economics 0
GE
genetics 6
HI
history 0
IM
immunology 4
IP
isolation & purification 0
ME
metabolism 6
PK
pharmacokinetics 0
PD
pharmacology 1
PH
physiology 12
PO
poisoning 0
RE
radiation effects 0
ST
standards 0
SD
supply & distribution 0
TU
therapeutic use 16
TO
toxicity 0
UL
ultrastructure 0
UR
urine 0

D Chemicals and Drugs
D08 Enzymes and Coenzymes 7
D08.622 Enzyme Precursors 68
D08.622.184 Chymotrypsinogen 5
D08.622.200 Complement Factor B 3
D08.622.355 Factor IX 82
D08.622.432 Factor VII 55
D08.622.471 Factor X 36
D08.622.490 Factor XI 4
D08.622.500 Factor XII 18
D08.622.505 Factor XIII 14
D08.622.509 Pepsinogens 16
D08.622.610 Plasminogen 43
D08.622.658 Prekallikrein 6
D08.622.705 Protein C 111
D08.622.709 Prothrombin 115
D08.622.885 Trypsinogen 22
D09 Carbohydrates 723
D09.400 Glycoconjugates 58
D09.400.430 Glycoproteins 637
D09.400.430.250 Activins 3
D09.400.430.500 ADAM Proteins 14
D09.400.430.532 Histidine-Rich Glycoprotein
D09.400.430.563 alpha 1-Antichymotrypsin 1
D09.400.430.594 alpha 1-Antitrypsin 79
D09.400.430.610 alpha-2-Antiplasmin 6
D09.400.430.618 alpha-2-HS-Glycoprotein 8
D09.400.430.625 Anti-Mullerian Hormone 48
D09.400.430.657 Asialoglycoproteins 5
D09.400.430.673 Avidin 14
D09.400.430.681 B-Cell Activating Factor 37
D09.400.430.685 4-1BB Ligand 1
D09.400.430.687 beta 2-Glycoprotein I 14
D09.400.430.688 CD27 Ligand
D09.400.430.700 Cholesterol Ester Transfer Proteins 45
D09.400.430.750 Clusterin 24
D09.400.430.775 Colony-Stimulating Factors 19
D09.400.430.780 Complement C1 Inhibitor Protein 45
D09.400.430.800 Fibrillins
D09.400.430.825 Glycated Proteins
D09.400.430.850 Glycodelin 1
D09.400.430.860 Hemopexin 31
D09.400.430.870 HSP47 Heat-Shock Proteins 4
D09.400.430.883 Inhibins 33
D09.400.430.887 Lactoferrin 32
D09.400.430.890 Membrane Glycoproteins 200
D09.400.430.900 Mucoproteins 77
D09.400.430.910 Myelin P0 Protein 8
D09.400.430.912 Osteonectin 11
D09.400.430.915 Protein C 111
D09.400.430.920 Protein S 36
D09.400.430.930 Proteoglycans 146
D09.400.430.940 Serum Amyloid P-Component 32
D09.400.430.950 Sialoglycoproteins 19
D09.400.430.952 Thyroglobulin 155
D09.400.430.955 Thyroxine-Binding Proteins 38
D09.400.430.960 Transcortin 8
D09.400.430.965 Tumor Necrosis Factor-alpha 1 305
D09.400.430.982 Vitronectin 7
D09.400.430.998 Zn-Alpha-2-Glycoprotein
D12 Amino Acids, Peptides, and Proteins 16
D12.776 Proteins 2 575
D12.776.124 Blood Proteins 909
D12.776.124.050 Acute-Phase Proteins 171
D12.776.124.117 beta 2-Glycoprotein I 14
D12.776.124.125 Blood Coagulation Factors 332
D12.776.124.197 Cholesterol Ester Transfer Proteins 45
D12.776.124.270 Fibrin 167
D12.776.124.335 Glycated Serum Proteins
D12.776.124.400 Hemoglobins 695
D12.776.124.486 Immunoproteins 14
D12.776.124.625 Platelet-Derived Growth Factor 39
D12.776.124.650 Protein C 111
D12.776.124.670 Protein S 36
D12.776.124.698 Retinol-Binding Proteins, Plasma 8
D12.776.124.727 Serum Albumin 489
D12.776.124.790 Serum Globulins 61
D12.776.124.862 Somatomedins 62
D12.776.124.885 Thyroxine-Binding Proteins 38
D12.776.124.900 Tumor Necrosis Factor-alpha 1 305
D12.776.124.920 Vitronectin 7
D12.776.395 Glycoproteins 637
D12.776.395.022 Activins 3
D12.776.395.033 ADAM Proteins 14
D12.776.395.045 alpha 1-Antichymotrypsin 1
D12.776.395.068 alpha 1-Antitrypsin 79
D12.776.395.080 alpha-2-Antiplasmin 6
D12.776.395.086 alpha-2-HS-Glycoprotein 8
D12.776.395.089 Anti-Mullerian Hormone 48
D12.776.395.092 CD27 Ligand
D12.776.395.140 Asialoglycoproteins 5
D12.776.395.175 Avidin 14
D12.776.395.191 B-Cell Activating Factor 37
D12.776.395.192 4-1BB Ligand 1
D12.776.395.195 beta 2-Glycoprotein I 14
D12.776.395.199 Cholesterol Ester Transfer Proteins 45
D12.776.395.207 Clusterin 24
D12.776.395.240 Colony-Stimulating Factors 19
D12.776.395.320 Complement C1 Inhibitor Protein 45
D12.776.395.341 Fibrillins
D12.776.395.351 Glycated Proteins
D12.776.395.361 Glycodelin 1
D12.776.395.401 Hemopexin 31
D12.776.395.420 HSP47 Heat-Shock Proteins 4
D12.776.395.439 Inhibins 33
D12.776.395.507 Lactoferrin 32
D12.776.395.550 Membrane Glycoproteins 200
D12.776.395.560 Mucoproteins 77
D12.776.395.570 Myelin P0 Protein 8
D12.776.395.600 Osteonectin 11
D12.776.395.635 Protein C 111
D12.776.395.642 Protein S 36
D12.776.395.650 Proteoglycans 146
D12.776.395.690 Serum Amyloid P-Component 32
D12.776.395.700 Sialoglycoproteins 19
D12.776.395.768 Thyroglobulin 155
D12.776.395.832 Thyroxine-Binding Proteins 38
D12.776.395.901 Transcortin 8
D12.776.395.930 Tumor Necrosis Factor-alpha 1 305
D12.776.395.970 Vitronectin 7
D12.776.395.985 Zn-Alpha-2-Glycoprotein
D12.776.811 Protein Precursors 131
D12.776.811.243 Enzyme Precursors 68
D12.776.811.243.184 Chymotrypsinogen 5
D12.776.811.243.200 Complement Factor B 3
D12.776.811.243.355 Factor IX 82
D12.776.811.243.432 Factor VII 55
D12.776.811.243.471 Factor X 36
D12.776.811.243.490 Factor XI 4
D12.776.811.243.500 Factor XII 18
D12.776.811.243.505 Factor XIII 14
D12.776.811.243.509 Pepsinogens 16
D12.776.811.243.610 Plasminogen 43
D12.776.811.243.658 Prekallikrein 6
D12.776.811.243.705 Protein C 111
D12.776.811.243.709 Prothrombin 115
D12.776.811.243.885 Trypsinogen 22
D23 Biological Factors 143
D23.113 Blood Coagulation Factor Inhibitors 112
D23.113.025 Antithrombin III 36
D23.113.475 Lupus Coagulation Inhibitor 47
D23.113.700 Protein C 111
D23.113.725 Protein S 36

Add