Receptor, ErbB-2 [receptor erbB-2]
- Terms
-
P185(c-neu)
protein c-erbB-2
protein Her-2
protoonkogenní protein erbB-2
protoonkogenní protein neu
receptor neu
-
Antigens, CD340
c-erbB-2 Protein
CD340 Antigen
Erb-b2 Receptor Tyrosine Kinases
erbB-2 Proto-Oncogene Protein
erbB-2 Receptor Protein-Tyrosine Kinase
HER-2 Proto-Oncogene Protein
Metastatic Lymph Node Gene 19 Protein
neu Proto-Oncogene Protein
Neu Receptor
Oncogene Protein HER-2
p185(c-neu)
p185erbB2 Protein
Proto-Oncogene Protein HER-2
Proto-oncogene Protein Neu
Proto-Oncogene Protein p185(neu)
Proto-Oncogene Proteins c-erbB-2
Receptor, Neu
Receptors, erbB-2
Tyrosine Kinase-type Cell Surface Receptor HER2
A cell surface protein-tyrosine kinase receptor that is overexpressed in a variety of ADENOCARCINOMAS. It has extensive homology to and heterodimerizes with the EGF RECEPTOR, the ERBB-3 RECEPTOR, and the ERBB-4 RECEPTOR. Activation of the erbB-2 receptor occurs through heterodimer formation with a ligand-bound erbB receptor family member.
- DUI
- D018719 MeSH Browser
- CUI
- M0028048
- Previous indexing
- Phosphoproteins (1985); Epidermal Growth Factor Receptor Protein-Tyrosine Kinase (1994); Proto-Oncogene Proteins (1986-1994)
- History note
- 2019 (1995)
- Public note
- 2019; for ERB-B2 RECEPTOR TYROSINE KINASES see ERBB RECEPTORS 2017-2019; see PROTO-ONCOGENE PROTEINS C-ERBB-2 1995-1999; for PROTO-ONCOGENE PROTEIN ERBB-2 see EPIDERMAL GROWTH FACTOR RECEPTOR PROTEIN-TYROSINE KINASE 1994, PROTO-ONCOGENE PROTEINS 1986-1994, and PHOSPHOPROTEINS 1985;
Allowable subheadings
- AD
- administration & dosage 17
- AG
- agonists 0
- AN
- analysis 65
- AI
- antagonists & inhibitors 165
- BI
- biosynthesis 12
- BL
- blood 13
- CH
- chemistry 1
- CL
- classification 2
- DF
- deficiency 1
- DE
- drug effects 106
- GE
- genetics 78
- HI
- history 0
- IM
- immunology 17
- IP
- isolation & purification 5
- ME
- metabolism 106
- PH
- physiology 4
- RE
- radiation effects 2
- TU
- therapeutic use 51
- UL
- ultrastructure 0