Multiple Endocrine Neoplasia Type 2b [mnohočetná endokrinní neoplazie typ 2B]
- Terms
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MEN 2B
MEN 3
nádory mnohočetné endokrinní typ 2b
-
MEA 2b
MEA IIb
MEN 2b
MEN 3
MEN IIb
MEN III
MEN2b
Mucosal Neuroma Syndrome
Multiple Endocrine Neoplasia, Type 2b
Multiple Endocrine Neoplasia, Type IIb
Multiple Endocrine Neoplasms Type 2b
Neoplasia, Multiple Endocrine Type 2b
Neoplasms, Multiple Endocrine Type 2b
Neuromata, Mucosal, With Endocrine Tumors
Wagenmann-Froboese Syndrome
Similar to MEN2A, it is also caused by mutations of the MEN2 gene, also known as the RET proto-oncogene. Its clinical symptoms include medullary carcinoma (CARCINOMA, MEDULLARY) of THYROID GLAND and PHEOCHROMOCYTOMA of ADRENAL MEDULLA (50%). Unlike MEN2a, MEN2b does not involve PARATHYROID NEOPLASMS. It can be distinguished from MEN2A by its neural abnormalities such as mucosal NEUROMAS on EYELIDS; LIP; and TONGUE, and ganglioneuromatosis of GASTROINTESTINAL TRACT leading to MEGACOLON. It is an autosomal dominant inherited disease.
- Annotation
- coordinate IM with specific endocrine/neoplasm pre-coordinates (IM) + specific histological type (IM) if pertinent
- DUI
- D018814 MeSH Browser
- CUI
- M0028167
- Previous indexing
- Multiple Endocrine Neoplasia (1975-1994)
- History note
- 1995; MEA III & MEN III see NEOPLASMS, MULTIPLE ENDOCRINE 1983-1994
- Public note
- 1995; MEA III & MEN III see NEOPLASMS, MULTIPLE ENDOCRINE 1983-1994
Allowable subheadings
- BL
- blood 0
- BS
- blood supply 0
- CF
- cerebrospinal fluid 0
- CI
- chemically induced 0
- CH
- chemistry 0
- CL
- classification 0
- CO
- complications 1
- CN
- congenital 0
- DI
- diagnosis 5
- DG
- diagnostic imaging 0
- DH
- diet therapy 0
- DT
- drug therapy 0
- EC
- economics 0
- EM
- embryology 0
- EN
- enzymology 0
- EP
- epidemiology 1
- EH
- ethnology 0
- ET
- etiology 1
- GE
- genetics 8
- HI
- history 0
- IM
- immunology 0
- ME
- metabolism 0
- MI
- microbiology 0
- MO
- mortality 1
- NU
- nursing 0
- PS
- parasitology 0
- PA
- pathology 3
- PP
- physiopathology 0
- PC
- prevention & control 0
- PX
- psychology 0
- RT
- radiotherapy 1
- RH
- rehabilitation 0
- SC
- secondary 0
- SU
- surgery 2
- TH
- therapy 1
- UL
- ultrastructure 0
- UR
- urine 0
- VE
- veterinary 0
- VI
- virology 0