CD40 Antigens [antigeny CD40]
- Terms
-
antigen CD40
CD40 antigen
CD40 antigeny
-
Antigens, CD40
CD40 Antigen
CDw40 Antigen
TNFRSF5 Receptor
Tumor Necrosis Factor Receptor Superfamily, Member 5
Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
- DUI
- D019013 MeSH Browser
- CUI
- M0028391
- Previous indexing
- Antigens, CD (1990-1995); Antigens, Differentiation, B-Lymphocyte (1988-1995)
- History note
- 2018 (1988)
- Public note
- 2018; see ANTIGENS, CD40 1996-2017, CD40 ANTIGEN 1989-95, and CDW40 ANTIGEN 1988-95; CD40 ANTIGEN was indexed under ANTIGENS, CD 1990-95; and under ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1989-95; CDW40 ANTIGEN was indexed under ANTIGENS, CD 1990-95; and under ANTIGENS, DIFFERENTIATION, B-LYMPHOCYTE 1988-95
Allowable subheadings
- AD
- administration & dosage
- AG
- agonists
- AN
- analysis 2
- AI
- antagonists & inhibitors 3
- BI
- biosynthesis 1
- BL
- blood 1
- CH
- chemistry
- CL
- classification
- DF
- deficiency
- DE
- drug effects
- GE
- genetics 2
- HI
- history
- IM
- immunology 5
- IP
- isolation & purification
- ME
- metabolism 4
- PH
- physiology 2
- RE
- radiation effects
- TU
- therapeutic use
- UL
- ultrastructure