Tumor Suppressor Protein p14ARF [nádorový supresorový protein p14ARF]

topical
4
Terms

Cdkn2a(p14ARF)
p14(ARF)
p14ARF
protein p14ARF

 

Cdkn2a(p14ARF)
p(ARF) Protein
p14(ARF)
p14ARF
p14ARF Protein

Persistent link   https://www.medvik.cz/link/D025803
Definition

A gene product of the p16 tumor suppressor gene (GENES, P16). It antagonizes the function of MDM2 PROTEIN (which regulates P53 TUMOR SUPPRESSOR PROTEIN by targeting it for degradation). p14ARF is produced from the beta mRNA transcript of the p16 gene. The other gene product, produced from the alternatively spliced alpha transcript, is CYCLIN-DEPENDENT KINASE INHIBITOR P16. Both p16 gene products have tumor suppressor functions.

DUI
D025803 MeSH Browser
CUI
M0255541
History note
2002(1996)
Public note
2002; TUMOR SUPPRESSOR PROTEIN P14ARF was indexed under P14ARF PROTEIN 2002-2005, & under PROTEINS 1996-2001

D Chemicals and Drugs
D12.776 Proteins 2 581
D12.776.167 Cell Cycle Proteins 330
D12.776.167.049 Aurora Kinases 4
D12.776.167.100 cdc25 Phosphatases 28
D12.776.167.163 Cohesins
D12.776.167.175 Cullin Proteins 7
D12.776.167.200 Cyclin-Dependent Kinases 231
D12.776.167.218 Cyclins 112
D12.776.167.254 GADD45 Proteins
D12.776.167.265 Geminin 1
D12.776.167.313 Mad2 Proteins 1
D12.776.167.457 NIMA-Related Kinases 4
D12.776.167.469 Polo-like Kinases
D12.776.167.504 Securin 1
D12.776.167.552 Separase 1
D12.776.167.576 Survivin 6
D12.776.624 Neoplasm Proteins 413
D12.776.624.776 Tumor Suppressor Proteins 269
D12.776.624.776.021 DCC Receptor
D12.776.624.776.100 BRCA1 Protein 103
D12.776.624.776.101 BRCA2 Protein 97
D12.776.624.776.418 Cystatin M
D12.776.624.776.482 Deubiquitinating Enzyme CYLD 1
D12.776.624.776.523 Kangai-1 Protein 1
D12.776.624.776.546 Kisspeptins 6
D12.776.624.776.610 Neurofibromin 1 14
D12.776.624.776.612 Neurofibromin 2 3
D12.776.624.776.633 Patched Receptors
D12.776.624.776.654 Promyelocytic Leukemia Protein 4
D12.776.624.776.695 PTEN Phosphohydrolase 50
D12.776.624.776.745 Retinoblastoma Protein 52
D12.776.624.776.760 Smad4 Protein 7
D12.776.624.776.772 Tumor Suppressor Protein p14ARF 4
D12.776.624.776.775 Tumor Suppressor Protein p53 762
D12.776.624.776.820 Tumor Protein p73 6
D12.776.624.776.960 WT1 Proteins 30

p19(ARF) protein, rat Chemical MeSH Browser